Role of Extracellular Calcium and Calcium Sensitization in the Anti-Contractile Effect of Perivascular Adipose Tissue in Pregnant Rat Aorta

Autor: Elsie Oommen, Mabayoje A. Oriowo, Lilly Verghese, Aishah Al-Jarallah

Publikováno v: Pharmacology. 104(5-6)

Previous studies have shown that the anti-contractile effect of the perivascular adipose tissue (PVAT) is attenuated in pregnancy. In the present investigation, we have examined the possibility that this loss of anti-contractile effect could be due t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e2e933af2ce6e1ed62c20e5306d02b
https://pubmed.ncbi.nlm.nih.gov/31484179

Loss of Anticontractile Effect of Perivascular Adipose Tissue on Pregnant Rats

Autor: Aishah Al-Jarallah, Mabayoje A. Oriowo

Publikováno v: Journal of Cardiovascular Pharmacology. 67:145-151

The present investigation examined the effect of pregnancy on the anticontractile effect of perivascular adipose tissue (PVAT) on the rat. Ring segments of the aorta, with and without PVAT, were set up in organ baths for isometric tension recording.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fbb7c77aeeff8b45360c0c28c75f984
https://doi.org/10.1097/fjc.0000000000000326

Molecular basis for the effects of zinc deficiency on spermatogenesis: An experimental study in the Sprague-dawley rat model

Autor: Elijah O. Kehinde, May Al-Maghrebi, Jehoram T. Anim, Anjum Memon, Alexander E. Omu, Chacko T Mathew, Mabayoje A. Oriowo, Majedah Al-Azemi, Florence E. Omu

Publikováno v: Indian Journal of Urology : IJU : Journal of the Urological Society of India
Indian Journal of Urology, Vol 31, Iss 1, Pp 57-64 (2015)

Introduction: The objective of this study is to investigate the molecular mechanisms underlying the effects of zinc deficiency on spermatogenesis in the Sprague-Dawley (SD) rat. Materials and Methods: Three groups of eight adult male SD rats were mai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597fd874001885cdf27c5a13f655cce4
http://europepmc.org/articles/PMC4300574

Rate of Homologous Desensitization and Internalization of the GLP-1 Receptor

Autor: Suleiman Al-Sabah, Ghina Shaaban, Mabayoje A. Oriowo

Publikováno v: Molecules, Vol 22, Iss 1, p 22 (2016)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 22; Issue 1; Pages: 22

The glucagon-like peptide-1 receptor (GLP-1R) is an important target in the treatment of type 2 diabetes mellitus. The aim of this study was to compare the rate of agonist stimulated desensitization and internalization of GLP-1R. To this end, an N-te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e815ea55a274da6c1158e1360258f7
http://www.mdpi.com/1420-3049/22/1/22

Colonic Inflammation Increases the Contribution of Muscarinic M2 Receptors to Carbachol-Induced Contraction of the Rat Colon

Autor: Islam U. Khan, Dina M. Jragh, Mabayoje A. Oriowo

Publikováno v: Medical Principles and Practice. 20:530-537

Objectives: Carbachol-induced contraction of the rat colon is impaired in rats with trinitrobenzene sulfonic acid (TNBS)-induced colitis. The main objective of this study was to examine the effect of colitis on the expression and function of muscarin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::208868a0d05159cd532e8f118426aec4
https://doi.org/10.1159/000328419