Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality.

Autor: Ishizawa J; The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA., Zarabi SF; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada., Davis RE; The University of Texas MD Anderson Cancer Center; Department of Lymphoma and Myeloma, Houston, TX 77030, USA., Halgas O; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada., Nii T; The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA., Jitkova Y; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Zhao R; The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA., St-Germain J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Heese LE; The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA., Egan G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Ruvolo VR; The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA., Barghout SH; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada., Nishida Y; The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA., Hurren R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Ma W; The University of Texas MD Anderson Cancer Center, Bioinformatics and Comp Biology, Houston, TX 77030, USA., Gronda M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Link T; The University of Texas MD Anderson Cancer Center, Genomic Medicine, Houston, TX 77030, USA., Wong K; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada., Mabanglo M; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada., Kojima K; The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA; Saga University, Division of Hematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Saga 849-8501, Japan., Borthakur G; The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA., MacLean N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Ma MCJ; The University of Texas MD Anderson Cancer Center; Department of Lymphoma and Myeloma, Houston, TX 77030, USA., Leber AB; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Minden MD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada., Houry W; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Chemistry, University of Toronto, Toronto, ON M5S 3H6, Canada., Kantarjian H; The University of Texas MD Anderson Cancer Center; Department of Leukemia, Houston, TX 77030, USA., Stogniew M; Oncoceutics, Inc., Philadelphia, PA 19104, USA., Raught B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada., Pai EF; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Schimmer AD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1L7, Canada. Electronic address: aaron.schimmer@uhn.ca., Andreeff M; The University of Texas MD Anderson Cancer Center, Molecular Hematology and Therapy, Department of Leukemia, Houston, TX 77030, USA; The University of Texas MD Anderson Cancer Center; Department of Leukemia, Houston, TX 77030, USA. Electronic address: mandreef@mdanderson.org.

Publikováno v: Cancer cell [Cancer Cell] 2019 May 13; Vol. 35 (5), pp. 721-737.e9. Date of Electronic Publication: 2019 May 02.

Strategies and mechanisms targeting Enterococcus faecalis biofilms associated with endodontic infections: a comprehensive review.

Autor: Shipeng Yang, Xiuping Meng, Yuqi Zhen, Quzhen Baima, Yu Wang, Xinmiao Jiang, Zhibo Xu

Publikováno v: Frontiers in Cellular & Infection Microbiology; 2024, p1-15, 15p

Accessing monomers from lignin through carbon-carbon bond cleavage.

Autor: Palumbo CT; Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO, USA., Ouellette ET; Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO, USA., Zhu J; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA., Román-Leshkov Y; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA. yroman@mit.edu., Stahl SS; Department of Chemistry. Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA. stahl@chem.wisc.edu., Beckham GT; Renewable Resources and Enabling Sciences Center, National Renewable Energy Laboratory, Golden, CO, USA. gregg.beckham@nrel.gov.; Center for Bioenergy Innovation, Oak Ridge, TN, USA. gregg.beckham@nrel.gov.

Publikováno v: Nature reviews. Chemistry [Nat Rev Chem] 2024 Nov; Vol. 8 (11), pp. 799-816. Date of Electronic Publication: 2024 Oct 04.

Design, Synthesis and Biological Evaluation of Bengamide Analogues as ClpP Activators.

Autor: Kong, Xue‐Qing^1,2, Wei, Bing‐Yan^1,2, Yu, Chen‐Xi^1,2, Guan, Xiang‐Na^1,2, Ma, Wei‐Ping¹, Liu, Gang¹, Yang, Cai‐Guang¹, Nan, Fa‐Jun^1,3 fjnan@simm.ac.cn

Publikováno v: Chinese Journal of Chemistry. Oct2020, Vol. 38 Issue 10, p1111-1115. 5p.

ONC201/TIC10 enhances durability of mTOR inhibitor everolimus in metastatic ER+ breast cancer.

Autor: Farmaki, Elena, Nath, Aritro, Emond, Rena, Karimi, Kimya L., Grolmusz, Vince K., Cosgrove, Patrick A., Bild, Andrea H.

Publikováno v: eLife; 9/29/2023, p1-21, 21p