Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maarten van de Klundert"'
Autor:
Marc Ringelhan, Svenja Schuehle, Maarten van de Klundert, Elena Kotsiliti, Marie-Laure Plissonnier, Suzanne Faure-Dupuy, Tobias Riedl, Sebastian Lange, Karin Wisskirchen, Frank Thiele, Cho-Chin Cheng, Detian Yuan, Valentina Leone, Ronny Schmidt, Juliana Hünergard, Fabian Geisler, Kristian Unger, Hana Algül, Roland M. Schmid, Roland Rad, Heiner Wedemeyer, Massimo Levrero, Ulrike Protzer, Mathias Heikenwalder
Publikováno v:
JHEP Reports, Vol 6, Iss 10, Pp 101128- (2024)
Background & Aims: Although most hepatocellular carcinoma (HCC) cases are driven by hepatitis and cirrhosis, a subset of patients with chronic hepatitis B develop HCC in the absence of advanced liver disease, indicating the oncogenic potential of hep
Externí odkaz:
https://doaj.org/article/ffc2a796c409435a93822963b60ef4ed
Autor:
Elena S Kim, Jun Zhou, Hu Zhang, Alexander Marchetti, Maarten van de Klundert, Dawei Cai, Xiaoyang Yu, Bidisha Mitra, Yuanjie Liu, Mu Wang, Ulrike Protzer, Haitao Guo
Publikováno v:
PLoS Pathogens, Vol 18, Iss 6, p e1010576 (2022)
Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA), serving as the viral persistence form and transcription template of HBV infection, hijacks host histone and non-histone proteins to form a minichromosome and utilizes posttranslational
Externí odkaz:
https://doaj.org/article/fd3d2222a0ed499f97ea9ee156e3874f
Autor:
Rafael Ceña-Diez, Aswathy Narayanan, Shilpa Ray, Maarten van de Klundert, Jimmy E Rodriguez, Johan Nilvebrant, Per-Åke Nygren, Ákos Végvári, Robert van Domselaar, Anders Sönnerborg
Publikováno v:
International Journal of Antimicrobial Agents. 61:106792
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abdf556893beb41a7280ff80c5f510b9
https://doi.org/10.1016/j.ijantimicag.2023.106792
https://doi.org/10.1016/j.ijantimicag.2023.106792
Autor:
Elena S. Kim, Jun Zhou, Hu Zhang, Alexander Marchetti, Maarten van de Klundert, Dawei Cai, Xiaoyang Yu, Bidisha Mitra, Yuanjie Liu, Mu Wang, Ulrike Protzer, Haitao Guo
Publikováno v:
PLoS Pathog. 18:e1010576 (2022)
Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA), serving as the viral persistence form and transcription template of HBV infection, hijacks host histone and non-histone proteins to form a minichromosome and utilizes posttranslational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49354e7f6cb5c4025c9ad74a7404818
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=65415
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=65415
Autor:
Ulrike Protzer, Fuwang Chen, Marc Ringelhan, Karin Wisskirchen, Oliver Quitt, Volker Bruss, Felix Bohne, Marvin M. Festag, Maxim Shevtsov, Luidmila Yakovleva, Maarten van de Klundert, Camille Sureau, Frank Momburg, Michaela Aichler, Britta S. Möhl, Julia Festag, Lili Zhao
Publikováno v:
Cell. Microbiol. 23:e13399 (2021)
Hepatitis B virus (HBV) infection is a major health threat causing 880,000 deaths each year. Available therapies control viral replication but do not cure HBV, leaving patients at risk to develop hepatocellular carcinoma. Here, we show that HBV envel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ddd5ced3739305d44b3aeb93369f8e
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63419
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=63419
Autor:
Marc Ringelhan, Firat Nebioglu, Christian Urban, Arie Geerlof, Jochen M. Wettengel, Martin Kächele, Maarten van de Klundert, Kristian Unger, Jessica Schneider, Julia Hess, Yuchen Xia, Andreas Oswald, Chunkyu Ko, Alisha N Jones, Felix Lasitschka, Peter Schirmacher, Ralf Bartenschlager, Mathias Heikenwalder, Ulrike Protzer, Daniela Stadler, Wen-Min Chou, Michael Sattler, Sabrina Schreiner, Romina Bester, Andreas Pichlmair
Publikováno v:
EMBO Reports
EMBO Rep. 22:e49568 (2021)
EMBO Rep. 22:e49568 (2021)
Hepatitis B virus (HBV) persists by depositing a covalently closed circular DNA (cccDNA) in the nucleus of infected cells that cannot be targeted by available antivirals. Interferons can diminish HBV cccDNA via APOBEC3‐mediated deamination. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36359062d0944dc463aae4603ed816b3
https://mediatum.ub.tum.de/doc/1624648/document.pdf
https://mediatum.ub.tum.de/doc/1624648/document.pdf
Autor:
Valentina D'Arienzo, David Durantel, Peter A C Wing, Emanuele Marchi, Ulrike Protzer, Efstathios S. Giotis, Peter Jianrui Liu, Maarten van de Klundert, Anna Maria Ortega-Prieto, Jane A. McKeating, Paul Klenerman, Andrea Magri, James M. Harris, Marcus Dorner, Jochen M. Wettengel, Thomas Michler
Publikováno v:
Scientific Reports
Sci. Rep. 10:14101 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Sci. Rep. 10:14101 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC) worldwide. The prolyl hydroxylase domain (PHD)-hypoxia inducible factor (HIF) pathway is a key mammalian oxygen sensing pathway and is frequently perturbed by pathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd78a21082caa373b96f8e43d06f5b2c
http://europepmc.org/articles/PMC7445281
http://europepmc.org/articles/PMC7445281
Autor:
David Durantel, Thomas Michler, James Harris, Ana Otega-Prieto, Ulrike Protzer, Peter A C Wing, Emanuele Marchi, Marcus Dorner, Paul Klenerman, Stathis Giotis, Valentina D'Arienzo, Jochen M. Wettengel, Maarten van de Klundert, Peter Jianrui Liu, Jane A. McKeating, Andrea Magri
Hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC) worldwide. The prolyl hydroxylase domain (PHD)-hypoxia inducible factor (HIF) pathway is a key mammalian oxygen sensing pathway and is frequently perturbed by pathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20274a1d861698dcfc689a969b500daf
https://doi.org/10.1101/2020.03.27.011841
https://doi.org/10.1101/2020.03.27.011841
Autor:
Marc Ringelhan, Chunkyu Ko, Maarten van de Klundert, Ke Zhang, Silke Arzberger, Maria Quasdorff, Carien M. Niessen, Ulrike Protzer, Margarete Odenthal, Gesa von Olshausen, Romina Bester
Publikováno v:
Oncotarget
Oncotarget 9, 33947-33960 (2018)
Oncotarget 9, 33947-33960 (2018)
Hepatitis B virus (HBV) infection is a prominent cause of hepatocellular carcinoma (HCC) but the underlying molecular mechanisms are complex and multiple pathways have been proposed such as the activation of the Wnt-/β-catenin-signalling and dysregu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a27f164fff57df34b6e174d70a47a36
http://europepmc.org/articles/PMC6188061
http://europepmc.org/articles/PMC6188061
Autor:
Jane A. McKeating, Valentina D'Arienzo, Efstathios S. Giotis, Ulrike Protzer, Jochen M. Wettengel, Emanuele Marchi, Andrea Magri, Thomas Michler, Peter A C Wing, David Durantel, Ana Maria Ortega-Prieto, Marcus Dorner, Peter Jianrui Liu, Paul Klenerman, Maarten van de Klundert, James M. Harris
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
Scientific Reports
Scientific Reports
Hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC) worldwide. The prolyl hydroxylase domain (PHD)-hypoxia inducible factor (HIF) pathway is a key mammalian oxygen sensing pathway and is frequently perturbed by pathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a5c848fd59c201d5bc7ff92356d71f
http://link.springer.com/article/10.1038/s41598-020-75963-0
http://link.springer.com/article/10.1038/s41598-020-75963-0