Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Maarten Van Dijk"'
Autor:
Eva-Lotta von Rüden, Heike Janssen-Peters, Maria Reiber, Roelof Maarten van Dijk, Ke Xiao, Isabel Seiffert, Ines Koska, Christina Hubl, Thomas Thum, Heidrun Potschka
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Patients with epilepsy have a high risk of developing psychiatric comorbidities, and there is a particular need for early detection of these comorbidities. Here, in an exploratory, hypothesis-generating approach, we aimed to identify microRN
Externí odkaz:
https://doaj.org/article/e6f7ad313be0417d8ea230b7629390a8
Autor:
Boldt, Lena, Koska, Ines, Maarten van Dijk, R., Talbot, Steven R., Miljanovic, Nina, Palme, Rupert, Bleich, André, Potschka, Heidrun
Publikováno v:
In Epilepsy & Behavior February 2021 115
Autor:
Verena Buchecker, Ann-Marie Waldron, R. Maarten van Dijk, Ines Koska, Matthias Brendel, Barbara von Ungern-Sternberg, Simon Lindner, Franz Josef Gildehaus, Sibylle Ziegler, Peter Bartenstein, Heidrun Potschka
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Background Stress exposure can significantly affect serotonergic signaling with a particular impact on 5-HT1A receptor expression. Positron emission tomography (PET) provides opportunities for molecular imaging of alterations in 5-HT1A recep
Externí odkaz:
https://doaj.org/article/d43b54d5f6174fbaa4a9e53b7f3ce284
Autor:
Danila Di Majo, Pierangelo Sardo, Giuseppe Giglia, Valentina Di Liberto, Francesco Paolo Zummo, Maria Grazia Zizzo, Gaetano Felice Caldara, Francesca Rappa, Giorgia Intili, Roelof Maarten van Dijk, Daniele Gallo, Giuseppe Ferraro, Giuditta Gambino
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 89 (2022)
Metabolic Syndrome (MetS) is an extremely complex disease. A non-balanced diet such as high-fat diet (HFD) induces metabolic dysfunction that could modify redox homeostasis. We here aimed at exploring redox homeostasis in male Wistar rats, following
Externí odkaz:
https://doaj.org/article/589dbdb073d341ff84352c701672e189
Autor:
Nina Miljanovic, Stefanie M. Hauck, R. Maarten van Dijk, Valentina Di Liberto, Ali Rezaei, Heidrun Potschka
Publikováno v:
Neurobiology of Disease, Vol 157, Iss , Pp 105423- (2021)
Background: Dravet syndrome is a rare, severe pediatric epileptic encephalopathy associated with intellectual and motor disabilities. Proteomic profiling in a mouse model of Dravet syndrome can provide information about the molecular consequences of
Externí odkaz:
https://doaj.org/article/cbb84c3f0ac14bdeba164ee825eecaf2
Autor:
Christine Henke, Kathrin Töllner, R. Maarten van Dijk, Nina Miljanovic, Thekla Cordes, Friederike Twele, Sonja Bröer, Vanessa Ziesak, Marco Rohde, Stefanie M. Hauck, Charlotte Vogel, Lisa Welzel, Tina Schumann, Diana M. Willmes, Anica Kurzbach, Nermeen N. El-Agroudy, Stefan R. Bornstein, Susanne A. Schneider, Jens Jordan, Heidrun Potschka, Christian M. Metallo, Rüdiger Köhling, Andreas L. Birkenfeld, Wolfgang Löscher
Publikováno v:
Neurobiology of Disease, Vol 143, Iss , Pp 105018- (2020)
In addition to tissues such as liver, the plasma membrane sodium-dependent citrate transporter, NaCT (SLC13A5), is highly expressed in brain neurons, but its function is not understood. Loss-of-function mutations in the human SLC13A5 gene have been a
Externí odkaz:
https://doaj.org/article/df9b3f253ba04e89ae8d4ee2953dca43
Autor:
Roelof Maarten van Dijk, Ines Koska, Andre Bleich, Rene Tolba, Isabel Seiffert, Christina Möller, Valentina Di Liberto, Steven Roger Talbot, Heidrun Potschka
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0230141 (2020)
Comparative severity assessment of animal models and experimental interventions is of utmost relevance for harm-benefit analysis during ethical evaluation, an animal welfare-based model prioritization as well as the validation of refinement measures.
Externí odkaz:
https://doaj.org/article/494f23c216884c7e9994810620de174e
Autor:
Valentina Di Liberto, R. Maarten van Dijk, Matthias Brendel, Ann-Marie Waldron, Christina Möller, Ines Koska, Isabel Seiffert, Fabio Gualtieri, Franz Josef Gildehaus, Barbara von Ungern-Sternberg, Magdalena Lindner, Sibylle Ziegler, Rupert Palme, Rainer Hellweg, Peter Gass, Peter Bartenstein, Heidrun Potschka
Publikováno v:
Neurobiology of Disease, Vol 118, Iss , Pp 9-21 (2018)
Psychiatric comorbidities are prevalent in patients with epilepsy and greatly contribute to the overall burden of disease. The availability of reliable biomarkers to diagnose epilepsy-associated comorbidities would allow for effective treatment and i
Externí odkaz:
https://doaj.org/article/5acfa05fe62c4f00a97d52eaf26cf3d3
Autor:
Michael Keck, Roelof Maarten van Dijk, Cornelia A. Deeg, Katharina Kistler, Andreas Walker, Eva-Lotta von Rüden, Vera Russmann, Stefanie M. Hauck, Heidrun Potschka
Publikováno v:
Neurobiology of Disease, Vol 112, Iss , Pp 119-135 (2018)
Information about epileptogenesis-associated changes in protein expression patterns is of particular interest for future selection of target and biomarker candidates.Bioinformatic analysis of proteomic data sets can increase our knowledge about molec
Externí odkaz:
https://doaj.org/article/adfff79d3bb9401a9f479550bb34cbd9
First 'Skin Depth' estimations using GEANT4 and FLUKA based simulations for CERN secondary beamlines
Autor:
Gian Luigi D’Alessandro, Dipanwita Banerjee, Lau Gatignon, Johannes Bernhard, Alexander Gerbershagen, Maarten van Dijk, Stephen Gibson
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 512:76-82
In order to have highly flexible secondary beamlines collimation is crucial. Collimators are blocks of material placed along the beamline that let the main beam pass within the collimator aperture limits, while most of the particles beyond it interac