Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maarten T Huisman"'
Autor:
Lei Zhang, Raffaella de Salvo, Sonja Trapp, Walter Wigger-Alberti, Ragna Williams, Lucie Delcour, Bart Rossel, Maarten T. Huisman
Publikováno v:
Dermatology and Therapy, Vol 10, Iss 5, Pp 1075-1088 (2020)
Abstract Introduction Over the last few years, it has been demonstrated that a moist environment enhances the healing process and reduces scar formation of wounds. Such moist conditions can be created and maintained using hydrogels. The aim of this s
Externí odkaz:
https://doaj.org/article/10fcd6e8a95048ce998f8a4de2217dc3
Autor:
Ragna Williams, Bart Rossel, Raffaella de Salvo, Lucie Delcour, Lei Zhang, Sonja Trapp, Maarten T Huisman, W. Wigger-Alberti
Publikováno v:
Dermatology and Therapy, Vol 10, Iss 5, Pp 1075-1088 (2020)
Dermatology and Therapy
Dermatology and Therapy
Introduction Over the last few years, it has been demonstrated that a moist environment enhances the healing process and reduces scar formation of wounds. Such moist conditions can be created and maintained using hydrogels. The aim of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a08f60e2c2e3b5989b33773cecca21
https://doi.org/10.1007/s13555-020-00432-5
https://doi.org/10.1007/s13555-020-00432-5
Autor:
Geert Mannens, Fabian Hulpia, Ken Kersemans, Caroline Dumolyn, Kim Braeckman, Christian Vanhove, Filip De Vos, Stef De Lombaerde, Maarten T. Huisman, Bjorn Verreet, Serge Van Calenbergh, Sara Neyt, Maarten Vliegen
Publikováno v:
Nuclear Medicine and Biology. 43:642-649
Introduction Hepatobiliary transport mechanisms are crucial for the excretion of substrate toxic compounds. Drugs can inhibit these transporters, which can lead to drug–drug interactions causing toxicity. Therefore, it is important to assess this e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d10a95e05fdb47d7f6774efcce8d61
https://doi.org/10.1016/j.nucmedbio.2016.07.001
https://doi.org/10.1016/j.nucmedbio.2016.07.001
Publikováno v:
European Journal of Pharmaceutical Sciences, 49, 5, pp. 819-28
European Journal of Pharmaceutical Sciences, 49, 819-28
European Journal of Pharmaceutical Sciences, 49, 819-28
Contains fulltext : 136174.pdf (Publisher’s version ) (Closed access) We studied if the clinical pharmacokinetics and drug-drug interactions (DDIs) of the sulfonylurea-derivative glibenclamide can be simulated via a physiologically-based pharmacoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aac395805ab90431b443f12a6741a4a2
https://hdl.handle.net/2066/136174
https://hdl.handle.net/2066/136174
Autor:
Mario Monshouwer, Maarten T. Huisman, Vivienne Verweij, Barbara Zarzycka, Sander B. Nabuurs, Rick Greupink, Frans G. M. Russel
Publikováno v:
Toxicological Sciences, 129, 35-48
Toxicological Sciences, 129, 1, pp. 35-48
Toxicological Sciences, 129, 1, pp. 35-48
Contains fulltext : 108286.pdf (Publisher’s version ) (Closed access) Na(+)-dependent taurocholate cotransporting polypeptide (NTCP, SLC10A1) is the main transporter facilitating the hepatic uptake of bile acids from the circulation. Consequently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5603d10614ae97e1e0c34089d1ddaf46
https://hdl.handle.net/2066/108286
https://hdl.handle.net/2066/108286
Autor:
Maarten T. Huisman, Ruurdtje Hoekstra, Thomas M. van Gulik, Tessa V. van der Hoeven, Robert A. F. M. Chamuleau, Geert A. A. Nibourg
Publikováno v:
Liver Transplantation. 16:1075-1085
To bridge patients with acute liver failure to transplantation or liver regeneration, a bioartificial liver (BAL) is urgently needed. A BAL consists of an extracorporeal bioreactor loaded with a bioactive mass that would preferably be of human origin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab4bfe1fecc7478758b0dfbf4eaddb1b
https://doi.org/10.1002/lt.22110
https://doi.org/10.1002/lt.22110
Autor:
Jan H.M. Schellens, Peter R. Wielinga, Puck Knipscheer, Maarten T. Huisman, Piet Borst, Glen Reid, Annemieke Kuil, Alfred H. Schinkel, Noam Zelcer, Pauline Breedveld
Publikováno v:
Journal of biological chemistry, 278(26), 23538-23544. American Society for Biochemistry and Molecular Biology Inc.
Multidrug resistance protein 2 (MRP2) belongs to the ATP binding cassette family of transporters. Its substrates include organic anions and anticancer drugs. We have used transport assays with vesicles derived from Sf9 insect cells overproducing MRP2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a3a42270d8234af84454200e6d979e
https://doi.org/10.1074/jbc.m303504200
https://doi.org/10.1074/jbc.m303504200
Autor:
Evita van de Steeg, Sieto Bosgra, Heleen M. Wortelboer, Maarten T. Huisman, Maria L. H. Vlaming, Miriam Verwei, Kitty C.M. Verhoeckx
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 65
In contrast to primary hepatocytes, estimating carrier-mediated hepatic disposition by using a panel of single transfected cell-lines provides direct information on the contribution of the individual transporters to the net disposition. The most dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c5018c6e3acd61a178201acf25e816
https://pubmed.ncbi.nlm.nih.gov/25261337
https://pubmed.ncbi.nlm.nih.gov/25261337
Publikováno v:
Journal of Clinical Investigation. 104:1441-1447
It was recently shown that naturally occurring Mdr1a mutant fetuses of the CF-1 outbred mouse stock have no placental Mdr1a P-glycoprotein (P-gp) and that this absence is associated with increased sensitivity to avermectin, a teratogenic pesticide. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515637ec1418276954ceccf8b5e80a59
https://doi.org/10.1172/jci7963
https://doi.org/10.1172/jci7963
Autor:
Lieselotte Moerman, Maarten Vliegen, Hilde De Man, Maarten T. Huisman, Geert Mannens, Christian Vanhove, Caroline Dumolyn, Filip De Vos, Sara Neyt
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 54(4)
Hepatic transport of 99mTc-mebrofenin through organic anion transport protein 1a and 1b (Oatp1a/1b) and multidrug resistance protein 2 (Mrp2) was investigated by small-animal SPECT. On the basis of the results, a noninvasive method to visualize and q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e698b1c2755b10a6dcfc528e2428f7fa
https://pubmed.ncbi.nlm.nih.gov/23440558
https://pubmed.ncbi.nlm.nih.gov/23440558