Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Maarten P. Hazenberg"'
Autor:
Ingrid A. Schrijver, Ghislain Opdenakker, Jon D. Laman, Marie-José Melief, H.M. Markusse, I Van Aelst, Maarten P. Hazenberg
Publikováno v:
Rheumatology. 40:438-446
textabstractOBJECTIVES: Peptidoglycan (PG), a component of Gram-positive bacteria, may be involved in rheumatoid arthritis (RA) because of its ability to induce production of proinflammatory cytokines, to induce arthritis in rodents, and its presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b58231675a9aeaf63cdc6eaa162226
https://doi.org/10.1093/rheumatology/40.4.438
https://doi.org/10.1093/rheumatology/40.4.438
Publikováno v:
Arthritis and rheumatism, 43(10), 2160-2168. John Wiley and Sons Inc.
Objective Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by intimal lining hyperplasia and massive infiltration of the synovial sublining by antigen-presenting cells (APCs), lymphocytes, and plasma cells. Peptidoglycan (PG)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7481ca46d448fe128323dcd265f858
https://doi.org/10.1002/1529-0131(200010)43:10<2160::aid-anr3>3.0.co
https://doi.org/10.1002/1529-0131(200010)43:10<2160::aid-anr3>3.0.co
Autor:
Marie-José Melief, Ingrid A. Schrijver, J.M. van Laar, Jon D. Laman, I. S. Klasen, Y. A. De Man, H. M. Markusse, Maarten P. Hazenberg
Publikováno v:
Clinical & Experimental Immunology, 122, 1-8. Wiley-Blackwell Publishing Ltd
SUMMARY The gut flora is believed to play a role in the pathogenesis of RA. Peptidoglycan, a major cell wall component of Gram-positive bacteria, is a candidate antigen because of its capability to trigger production of proinflammatory cytokines, to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4f39b22ccb50e849ce10e066e154a0
https://pure.eur.nl/en/publications/81b66d07-a712-44cf-87a0-1181f3ce0128
https://pure.eur.nl/en/publications/81b66d07-a712-44cf-87a0-1181f3ce0128
Autor:
Maarten P. Hazenberg, Doede J. Binnema, Leo M. C. van Lieshout, Johanneke G. H. Ruseler-van Embden
Publikováno v:
Clinical Science, 95, 425-433. Portland Press, Ltd.
1.An earlier study by our group revealed that the viscosity of faeces from patients with Crohn's disease is significantly lower than that of healthy subjects. This is due to low concentrations of a high-molecular-mass carbohydrate, probably of bacter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b465f9dc43bc9d34f655a2bc55ef359
https://pure.eur.nl/en/publications/d7fa3a0e-e456-4258-a2a3-4347067b7fd9
https://pure.eur.nl/en/publications/d7fa3a0e-e456-4258-a2a3-4347067b7fd9
Autor:
Maarten P. Hazenberg, Marie-José Melief, J. Calafat, R.W.M. van den Beemd, Maarten A. Hoijer, D. Roos, J. J. M. Van Dongen
Publikováno v:
Blood. 90:1246-1254
N-acetylmuramyl-L-alanine amidase (NAMLAA) specifically degrades peptidoglycan, which is a major component of bacterial cell walls with strong inflammatory properties. For instance, peptidoglycan is capable of stimulating peripheral blood cells to re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d5ea27fe01113beabee3d056eb01fcd
https://doi.org/10.1182/blood.v90.3.1246
https://doi.org/10.1182/blood.v90.3.1246
Publikováno v:
Annals of Neurology. 38:170-175
In Guillain-Barré syndrome antibodies to GM1 and the presence of an antecedent Campylobacter jejuni infection are correlated with a more severe course of the disease. From a group of 137 consecutive GBS patients, 11 sera had elevated titers of anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f13909e17b27ad8644ce4b40435120
https://doi.org/10.1002/ana.410380208
https://doi.org/10.1002/ana.410380208
Autor:
Maarten A. Hoijer, Maarten P. Hazenberg, Marie-José Melief, F. Eulderink, C.G. van Helden-Meeuwsen
Publikováno v:
Infection and Immunity. 63:1652-1657
In previous studies, we showed that peptidoglycan polysaccharides from anaerobic bacteria normally present in the human gut induced severe chronic joint inflammation in rats. Our hypothesis is that peptidoglycan from the gut flora is involved in perp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7dfc869579b9da43472b5d73dc4804
https://doi.org/10.1128/iai.63.5.1652-1657.1995
https://doi.org/10.1128/iai.63.5.1652-1657.1995
Autor:
P.A. van Doorn, Hubert P. Endtz, Maarten P. Hazenberg, F. G. A. Van Der Meche, H. A. M. Achtereekte, Bart C. Jacobs
Publikováno v:
Annals of Neurology. 37:260-264
Three patients who had diarrhea prior to the development of Miller Fisher syndrome are presented. Campylobacter jejuni was isolated from stool specimens from all patients. High titers of anti-GQ1b IgG antibodies were demonstrated in the serum of thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae088f0ba93fc68a375d851c72e66600
https://doi.org/10.1002/ana.410370218
https://doi.org/10.1002/ana.410370218
Publikováno v:
Rheumatology. 34:1112-1116
In previous studies using and animal model human bacterial flora-derived peptidoglycan Polysaccharides were shown to be arthropathic after a single subcutaneous injection. A prerequisite for proof of the hypothesis that bacterial products from the no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efaf362cef0bf0bdfa1ef454dd88d48d
https://doi.org/10.1093/rheumatology/34.12.1112
https://doi.org/10.1093/rheumatology/34.12.1112
Autor:
I. S. Klasen, Maarten P. Hazenberg, Marie-José Melief, G. Hoke, H. Hooijkaas, W.R. Schouten, H. de Visser, A.G.S. van Halteren, M. van Blankenstein
Publikováno v:
Clinical Immunology and Immunopathology. 71:303-308
Interestingly, using a monoclonal antibody, peptidoglycan-polysaccharide complexes (PPC) were detected intracellularly in the mucosa and submucosa of the bowel wall of Crohn's disease (CD) patients. PPC are the main constituents of the gram-positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cb8a981c112cf7cd83b72146755d9b
https://doi.org/10.1006/clin.1994.1090
https://doi.org/10.1006/clin.1994.1090