Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Maarten Jacquemyn"'
Publikováno v:
Biosensors, Vol 14, Iss 8, p 362 (2024)
Orthoflaviviruses cause a major threat to global public health, and no antiviral treatment is available yet. Zika virus (ZIKV) entry, together with many other viruses, is known to be enhanced by phosphatidylserine (PS) receptors such as T-cell immuno
Externí odkaz:
https://doaj.org/article/db8590e2b8b44b2aa0598dee967d1205
Autor:
Sabine Tejpar, Abhishek D Garg, Louis Boon, Massimiliano Mazzone, Jenny Sprooten, Isaure Vanmeerbeek, Stefan Naulaerts, Raquel Salvador, Jannes Govaerts, Rosa Trotta, Samantha Pretto, Shikang Zhao, Sarah Trusso Cafarello, Joren Verelst, Maarten Jacquemyn, Martyna Pociupany, Susan M Schlenner, Dirk Daelemans
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4d74b171dccc4687ac58e89d21d9fc32
Autor:
Keren Lasker, Steven Boeynaems, Vinson Lam, Daniel Scholl, Emma Stainton, Adam Briner, Maarten Jacquemyn, Dirk Daelemans, Ashok Deniz, Elizabeth Villa, Alex S. Holehouse, Aaron D. Gitler, Lucy Shapiro
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
“Intracellular phase separation is emerging as a universal principle for organizing biochemical reactions in time and space. Here the authors show that PopZ condensate dynamics support cell division and using PopZ modular architecture, the tunable
Externí odkaz:
https://doaj.org/article/dea291a67d0a47ba85a97b024b6dede1
Autor:
Eline Boons, Tatiane C. Nogueira, Tim Dierckx, Soraya Maria Menezes, Maarten Jacquemyn, Sharon Tamir, Yosef Landesman, Lourdes Farré, Achiléa Bittencourt, Keisuke Kataoka, Seishi Ogawa, Robert Snoeck, Graciela Andrei, Johan Van Weyenbergh, Dirk Daelemans
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 2, Pp 1-5 (2021)
Externí odkaz:
https://doaj.org/article/649a07bebf2b446c9c218bca5122f2e6
Autor:
Jasper Edgar Neggers, Bert Kwanten, Tim Dierckx, Hiroki Noguchi, Arnout Voet, Lotte Bral, Kristien Minner, Bob Massant, Nicolas Kint, Michel Delforge, Thomas Vercruysse, Erkan Baloglu, William Senapedis, Maarten Jacquemyn, Dirk Daelemans
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Cancer therapy drugs are designed to target genetic vulnerabilities, but loss-of-function screens often fail to identify essential genes in drug mechanism studies. Here the authors demonstrate CRISPRres, which exploits in-frame variation generated by
Externí odkaz:
https://doaj.org/article/9dbf9e90c64d440ea8f766544059bc01
Autor:
Eline Boons, Els Vanstreels, Maarten Jacquemyn, Tatiane C. Nogueira, Jasper E. Neggers, Thomas Vercruysse, Joost van den Oord, Sharon Tamir, Sharon Shacham, Yosef Landesman, Robert Snoeck, Christophe Pannecouque, Graciela Andrei, Dirk Daelemans
Publikováno v:
EBioMedicine, Vol 2, Iss 9, Pp 1102-1113 (2015)
Infection with HIV ultimately leads to advanced immunodeficiency resulting in an increased incidence of cancer. For example primary effusion lymphoma (PEL) is an aggressive non-Hodgkin lymphoma with very poor prognosis that typically affects HIV infe
Externí odkaz:
https://doaj.org/article/032494f4bfb3424aa0ed97a02a53817f
Autor:
Wenting Guo, Haibo Wang, Arun Kumar Tharkeshwar, Julien Couthouis, Elke Braems, Pegah Masrori, Evelien Van Schoor, Yannan Fan, Karan Ahuja, Matthieu Moisse, Maarten Jacquemyn, Rodrigo Furtado Madeiro da Costa, Madhavsai Gajjar, Sriram Balusu, Tine Tricot, Laura Fumagalli, Nicole Hersmus, Rekin's Janky, Francis Impens, Pieter Vanden Berghe, Ritchie Ho, Dietmar Rudolf Thal, Rik Vandenberghe, Muralidhar L. Hegde, Siddharthan Chandran, Bart De Strooper, Dirk Daelemans, Philip Van Damme, Ludo Van Den Bosch, Catherine Verfaillie
Publikováno v:
Guo, W, Wang, H, Kumar Tharkeshwar, A, Couthouis, J, Braems, E, Masrori, P, Van Schoor, E, Fan, Y, Ahuja, K, Moisse, M, Jacquemyn, M, Furtado Madeiro Da Costa, R, Gajjar, M, Balusu, S, Tricot, T, Fumagalli, L, Hersmus, N, Janky, R, Impens, F, Vanden Berghe, P, Ho, R, Thal, D R, Vandenberghe, R, Hegde, M L, Chandran, S, De Strooper, B, Daelemans, D, Van Damme, P, Van Den Bosch, L & Verfaillie, C 2022, ' CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity ', Alzheimer's & Dementia . https://doi.org/10.1002/alz.12760
ALZHEIMERS & DEMENTIA
ALZHEIMERS & DEMENTIA
INTRODUCTION: The most common genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are hexanucleotide repeats in chromosome 9 open reading frame 72 (C9orf72). These repeats produce dipeptide repeat proteins with poly
Autor:
Dirk Daelemans, Jan Cools, Antonis Dagklis, Sharon Shacham, William Senapedis, Yosef Landesman, Erkan Baloglu, Veit Hornung, Jonathan L. Schmid-Burgk, Els Vanstreels, Maarten Jacquemyn, Jasper E. Neggers, Jolien De Bie, Thomas Vercruysse
Purpose: Human exportin-1 (XPO1) is the key nuclear-cytoplasmic transport protein that exports different cargo proteins out of the nucleus. Inducing nuclear accumulation of these proteins by inhibiting XPO1 causes cancer cell death. First clinical va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::367718e76ff8764241a11a075e43f436
https://doi.org/10.1158/1078-0432.c.6526341
https://doi.org/10.1158/1078-0432.c.6526341
Autor:
Dirk Daelemans, Jan Cools, Antonis Dagklis, Sharon Shacham, William Senapedis, Yosef Landesman, Erkan Baloglu, Veit Hornung, Jonathan L. Schmid-Burgk, Els Vanstreels, Maarten Jacquemyn, Jasper E. Neggers, Jolien De Bie, Thomas Vercruysse
Movie S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16bfaf1fa5e89077545809a366bc265a
https://doi.org/10.1158/1078-0432.22466529.v1
https://doi.org/10.1158/1078-0432.22466529.v1
Autor:
Dirk Daelemans, Jan Cools, Antonis Dagklis, Sharon Shacham, William Senapedis, Yosef Landesman, Erkan Baloglu, Veit Hornung, Jonathan L. Schmid-Burgk, Els Vanstreels, Maarten Jacquemyn, Jasper E. Neggers, Jolien De Bie, Thomas Vercruysse
Supplementary Table 1 - EC50 values for KPT-8602 and KPT-330 in different leukemia cells Supplementary Table 2 - EC50 values for KPT-8602 in wild-type versus XPO1C528S mutant cell lines Figure S1 - High content images of HeLa cells stably expressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070b01e8b207f4c6f74e09a84624b2f5
https://doi.org/10.1158/1078-0432.22466523.v1
https://doi.org/10.1158/1078-0432.22466523.v1