Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Maarten H P, Kole"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
How myelin controls energy usage in different neuronal cell types remains unclear. Here, using viral tools, live imaging and ultrastructural data, the authors show that in contrast to excitatory axons interneuron myelination boosts the clustering of
Externí odkaz:
https://doaj.org/article/5cfcb6f9cc884235ae82f33f9d8813eb
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
It is difficult to apply SMLM to complex biological tissues. Here the authors report REALM, Robust and Effective Adaptive Optics in Localisation Microscopy, to improve SMLM in tissue and use this to resolve the organisation of spectrin in the axon in
Externí odkaz:
https://doaj.org/article/dee4cf76855b40cbb4c28ab779681f9f
Autor:
Nora Jamann, Dominik Dannehl, Nadja Lehmann, Robin Wagener, Corinna Thielemann, Christian Schultz, Jochen Staiger, Maarten H. P. Kole, Maren Engelhardt
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The axon initial segment (AIS) is critical for action potential initiation and implicated in the regulation of neuronal excitability. The authors describe bidirectional AIS plasticity in a behaviourally relevant context, revealing that the AIS acts i
Externí odkaz:
https://doaj.org/article/3448fcd546cd402188415c970a652661
Autor:
Sharlen Moore, Martin Meschkat, Torben Ruhwedel, Andrea Trevisiol, Iva D. Tzvetanova, Arne Battefeld, Kathrin Kusch, Maarten H. P. Kole, Nicola Strenzke, Wiebke Möbius, Livia de Hoz, Klaus-Armin Nave
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Oligodendrocytes myelinate and metabolically support axons. The role of myelination in information processing beyond regulation of conduction velocity is unclear. Here, the authors show that myelination contributes to sustained stimulus perception in
Externí odkaz:
https://doaj.org/article/a09d02aa6f5a496d8ea875c4ea276d34
Autor:
Nicole I. Wolf, Marjolein Breur, Bonnie Plug, Shanice Beerepoot, Aimee S. R. Westerveld, Diane F. vanRappard, Sharon I. deVries, Maarten H. P. Kole, Adeline Vanderver, Marjo S. van derKnaap, Caroline A. Lindemans, Peter M. vanHasselt, Jaap J. Boelens, Ulrich Matzner, Volkmar Gieselmann, Marianna Bugiani
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 2, Pp 169-180 (2020)
Abstract Objective In metachromatic leukodystrophy, a lysosomal storage disorder due to decreased arylsulfatase A activity, hematopoietic stem cell transplantation may stop brain demyelination and allow remyelination, thereby halting white matter deg
Externí odkaz:
https://doaj.org/article/d28d2053d0be445fa9404b88dad87b05
Autor:
Aletta M. R. van den Bosch, Sophie Hümmert, Anna Steyer, Torben Ruhwedel, Jörg Hamann, Joost Smolders, Klaus‐Armin Nave, Christine Stadelmann, Maarten H. P. Kole, Wiebke Möbius, Inge Huitinga
Publikováno v:
Annals of Neurology, 93(4), 856-870. John Wiley & Sons Inc.
Annals of neurology. John Wiley and Sons Inc.
Annals of Neurology
Annals of neurology. John Wiley and Sons Inc.
Annals of Neurology
Objective: Changes in the normal-appearing white matter (NAWM) in multiple sclerosis (MS) may contribute to disease progression. Here, we systematically quantified ultrastructural and subcellular characteristics of the axon–myelin unit in MS NAWM a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e9edecb072614d58500229c53831f9
http://www.scopus.com/inward/record.url?scp=85146076920&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85146076920&partnerID=8YFLogxK
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2019)
Combining fluorescence and transmitted light sources for microscopy is an invaluable method in cellular neuroscience to probe the molecular and cellular mechanisms of cells. This approach enables the targeted recording from fluorescent reporter prote
Externí odkaz:
https://doaj.org/article/b946fed491504856aa7efca429c2caf6
Autor:
Emma M J Passchier, Sven Kerst, Eelke Brouwers, Eline M C Hamilton, Quinty Bisseling, Marianna Bugiani, Quinten Waisfisz, Philip Kitchen, Lucas Unger, Marjolein Breur, Leoni Hoogterp, Sharon I de Vries, Truus E M Abbink, Maarten H P Kole, Rob Leurs, Henry F Vischer, Maria S Brignone, Elena Ambrosini, François Feillet, Alfred P Born, Leon G Epstein, Huibert D Mansvelder, Rogier Min, Marjo S van der Knaap
Publikováno v:
Brain. Oxford University Press
Brain oedema is a life-threatening complication of various neurological conditions. Understanding molecular mechanisms of brain volume regulation is critical for therapy development. Unique insight comes from monogenic diseases characterized by chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ab8f0d13111ae7eb9457056d03141c
https://doi.org/10.1093/brain/awad146
https://doi.org/10.1093/brain/awad146
Autor:
Koen Seignette, Nora Jamann, Paolo Papale, Huub Terra, Ralph P. O. Porneso, Leander de Kraker, Chris van der Togt, Maaike van der Aa, Paul Neering, Emma Ruimschotel, Pieter R. Roelfsema, Jorrit S. Montijn, Matthew W. Self, Maarten H. P. Kole, Christiaan N. Levelt
Detailed characterization of interneuron subtypes in primary visual cortex (V1) has greatly contributed to understanding visual perception, yet the role of chandelier cells (ChCs) in visual processing remains poorly characterized. Using viral tracing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528bec5305c29838c42969ac0cf45bfa
https://doi.org/10.1101/2023.04.21.537780
https://doi.org/10.1101/2023.04.21.537780
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Satellite oligodendrocytes (s-OLs) are characterised by their close proximity to neocortical pyramidal cells. Here, the authors find that s-OLs myelinate axons and activity of host neurons evokes inward K+ currents in s-OLs which may work to modulate
Externí odkaz:
https://doaj.org/article/3ea43843d7fb401898b5fb11947e84f0