Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Maarten E A, Reith"'
Autor:
Sandhya Kortagere, Maarten E. A. Reith, Zhicheng Lin, Hui Sun, Aurelio Galli, Corinde E. Wiers, Nora D. Volkow, Manju A. Kurian
Publikováno v:
Molecular Psychiatry. 27:1031-1046
The human dopamine transporter gene SLC6A3 has been consistently implicated in several neuropsychiatric diseases but the disease mechanism remains elusive. In this risk synthesis, we have concluded that SLC6A3 represents an increasingly recognized ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1010892873eeb54d3417fd252fe8cd68
https://doi.org/10.1038/s41380-021-01341-5
https://doi.org/10.1038/s41380-021-01341-5
Autor:
Sanjib Gogoi, Tamara Antonio, Aloke K. Dutta, Seenuvasan Vedachalam, Sandhya Kortagere, Maarten E. A. Reith, Soumava Santra
Publikováno v:
ACS Chemical Neuroscience. 12:1406-1418
We have carried out a structural exploration of (2S,4R,5R)-2-(bis(4-fluorophenyl)methyl)-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol (D-473) to investigate the influence of various functional groups on its aromatic ring, the introduction of he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfbca738b79aa20059df271781e81b75
https://doi.org/10.1021/acschemneuro.1c00078
https://doi.org/10.1021/acschemneuro.1c00078
Autor:
Anand Kant Das, Gerhard J. Schütz, Dino Luethi, Dániel Szöllősi, Thomas Stockner, Kumaresan Jayaraman, Maarten E. A. Reith, Harald H. Sitte
Publikováno v:
Journal of Neurochemistry
Transporters of the solute carrier 6 (SLC6) family mediate the reuptake of neurotransmitters such as dopamine, norepinephrine, serotonin, GABA, and glycine. SLC6 family members are 12 transmembrane helix‐spanning proteins that operate using the tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60881a6aaebb1dc2e6492776176b1002
http://europepmc.org/articles/PMC8247324
http://europepmc.org/articles/PMC8247324
Publikováno v:
Pharmacological Research. 143:48-57
Agonist-induced internalization of G protein-coupled receptors (GPCRs) is a significant step in receptor kinetics and is known to be involved in receptor down-regulation. However, the dopamine D3 receptor (D3R) has been an exception wherein agonist i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e2cc765a99cfe1ac77dabdb35e23d2
https://doi.org/10.1016/j.phrs.2019.03.003
https://doi.org/10.1016/j.phrs.2019.03.003
Autor:
Ole V. Mortensen, Courtney A. Marshall, Zachary D. Brodnik, Sandhya Kortagere, Maarten E. A. Reith, Barry D. Waterhouse, Rodrigo A. España, Jed S. Shumsky
Publikováno v:
Neuropharmacology. 148:178-188
Catecholamine transmitters dopamine (DA) and norepinephrine (NE) regulate prefrontal cortical (PFC) circuit activity and PFC-mediated executive functions. Accordingly, pharmacological agents that influence catecholamine neurotransmission exert promin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de4285f535d726e70a3019da9cd39f6
https://doi.org/10.1016/j.neuropharm.2019.01.003
https://doi.org/10.1016/j.neuropharm.2019.01.003
Autor:
Aloke K Dutta, Soumava Santra, Horrick Sharma, Chandrashekhar Voshavar, Liping Xu, Omar Mabrouk, Tamara Antonio, Maarten E A Reith
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113420 (2014)
Major depressive disorder (MDD) is a debilitating disease affecting a wide cross section of people around the world. The current therapy for depression is less than adequate and there is a considerable unmet need for more efficacious treatment. Dopam
Externí odkaz:
https://doaj.org/article/d7fd44233b374865ad98253b93804f2d
Autor:
Maarten E A, Reith, Sandhya, Kortagere, Corinde E, Wiers, Hui, Sun, Manju A, Kurian, Aurelio, Galli, Nora D, Volkow, Zhicheng, Lin
Publikováno v:
Molecular psychiatry. 27(2)
The human dopamine transporter gene SLC6A3 has been consistently implicated in several neuropsychiatric diseases but the disease mechanism remains elusive. In this risk synthesis, we have concluded that SLC6A3 represents an increasingly recognized ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9cde781796bcabf8dd8f809730e93177
https://pubmed.ncbi.nlm.nih.gov/34650206
https://pubmed.ncbi.nlm.nih.gov/34650206
Autor:
Tamara Antonio, Steven R Childers, Richard B Rothman, Christina M Dersch, Christine King, Martin Kuehne, William G Bornmann, Amy J Eshleman, Aaron Janowsky, Eric R Simon, Maarten E A Reith, Kenneth Alper
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77262 (2013)
The iboga alkaloids are a class of small molecules defined structurally on the basis of a common ibogamine skeleton, some of which modify opioid withdrawal and drug self-administration in humans and preclinical models. These compounds may represent a
Externí odkaz:
https://doaj.org/article/15dd1576a36a4ceaa239a8d0e66074b4
Dopamine agonists comprise a major class of therapeutics used for treating Parkinson's disease. They are commonly employed as monotherapy mainly in the early stage of Parkinson's disease to delay levodopa-induced motor complications or combined with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1082585085d01c048c96a9f3010c51d
https://doi.org/10.1016/b978-0-12-815946-0.00026-0
https://doi.org/10.1016/b978-0-12-815946-0.00026-0
Autor:
Kyle C. Schmitt, Maarten E. A. Reith
Publikováno v:
PLoS ONE, Vol 7, Iss 1 (2012)
Externí odkaz:
https://doaj.org/article/2de419e5b24b4451b37fce205af5dfb0