Výsledky vyhledávání - "Maarten Alink"

ChemInform Abstract: Effects of Asymmetry and Bulky Substituents in Amine Ligands of cis-Di( amine)dichloroplatinum Complexes on the Structure of Adducts Formed with Adjacent Guanines in Nucleic Acids

Autor: Kenji Inagaki, Jan Reedijk, Maarten Alink, Hideaki Nakahara

Publikováno v: ChemInform. 22

Platinum adducts obtained from the reaction of 3′-O,5′-O-phosphodiguanosine, r(GpG), with the asymmetric complexes cis-[PtCl2L(L′)](L = NH3; L′= alkylamine such as NH2Me, NH2Et, NHMe2and NHEt2; LL′=N,N-dimethylethylenediamine) have been str

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df56376dace2c2687f63652dfa5bc4bb
https://doi.org/10.1002/chin.199133245

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Conformation of platinum-trinucleotide adduct Pt(dien)[d(ApGpA)-N7(2)] in the solid state and in aqueous solution, as determined with single-crystal x-ray diffraction and high-resolution NMR spectroscopy in solution

Autor: Carla J. van Garderen, Rudolf A. G. de Graaff, Jan Reedijk, Maarten Alink, Fransje J. Dijt, Gert Admiraal, Cornelis Altona

Publikováno v: Journal of the American Chemical Society. 114:930-938

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2cca2b1accdcea43b2ff0fb86dcdd5b8
https://doi.org/10.1021/ja00029a021

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Characterization of (1,2-cyclohexanediamine)platinum(II) isomers and their d(GpG) adducts by means of proton NMR spectroscopy. A minor structural change induced by the isomers

Autor: Kenji Inagaki, Maarten Alink, Hideaki Nakahara, Yoshinori Kidani

Publikováno v: Inorganic Chemistry. 29:4496-4500

Diastereoisomers obtained from the reaction of d(GpG) with the three isomers of Pt(1,2-cyclohexanediamine) 2+ have been investigated by means of high-resolution 1 H NMR spectroscopy. The reaction of d(GpG) with each Pt(R,R/S,S/R,S-dach) 2+ gave a G-N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5d4580dd5735a75e651c6ba581db79c8
https://doi.org/10.1021/ic00347a032

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Unusual isomerization reaction of a platinum-dinucleotide compound

Autor: Kenji Inagaki, Jan Reedijk, Akinori Nagai, Yoshinori Kidani, Maarten Alink

Publikováno v: Inorganic Chemistry. 29:2183-2185

The reaction between a bifunctional platinum complex and nucleic acid base occurs via a two-step mechanism, and the first step is normally a preferential binding to the N7 site of a guanine. The present paper mainly describes results obtained about t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8d2b415d6ea05cc798feb9079469fe9
https://doi.org/10.1021/ic00336a031

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Cytotoxicity of asymmetric platinum complexes against L-1210 cells. Effect of bulky substituents

Autor: Hideaki Nakahara, Takayoshi Hirano, Yoshinori Kidani, Takashi Fukai, Kenji Inagaki, Maarten Alink

Publikováno v: Chemicalpharmaceutical bulletin. 38(10)

The asymmetric platinum complexes cis-Pt(LL')Cl2 (L = NH3, L' = CH3NH2, (CH3)2NH, C2H5NH2 and (C2H5)2NH and LL' = N,N-dimethylethylenediamine),--one of the NH3 groups of cis-Pt(NH3)2Cl2 was substituted by alkylamine--, were synthesized and their cyto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3f14c37b52a5366624a0ed8b58d6c96
https://pubmed.ncbi.nlm.nih.gov/2076570

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Effects of asymmetry and bulky substituents in amine ligands of cis-Di(amine)dichloroplatinum complexes on the structure of adducts formed with adjacent guanines in nucleic acids

Autor: Kenji Inagaki, Jan Reedijk, Maarten Alink, Hideaki Nakahara

Publikováno v: Journal of the Chemical Society, Dalton Transactions. :1337

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fa22783948a6935c71a7114b9ecd667
https://doi.org/10.1039/dt9910001337

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Reaction of symmetrically and asymmetrically substituted derivatives of cisplatin with r(ApG). Influence of the nonleaving groups on structures and kinetics

Autor: Hideaki Nakahara, Kenji Inagaki, Mamoru Nakanishi, Takayoshi Hirano, Maarten Alink, Yoshinori Kidani, Jan Reedijk

Publikováno v: Scopus-Elsevier

Reactions between symmetrically and asymmetrically substituted cis-platinum amine compounds with the dinucleotide r(ApG) have been studied. The symmetric cis-platinum amine compounds (general formulae cis-PtCl 2 (LL) 2 , L=NH 3 , alkylamine, also LL=

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103e39a4c00494327279c3c1590a20ff
http://www.scopus.com/inward/record.url?eid=2-s2.0-0007737885&partnerID=MN8TOARS

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