Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maarit Vaalamo"'
Autor:
Maarit Vaalamo, Johanna Höök-Nikanne, Rosalind M. Hembry, Oona Rechardt, Lari Häkkinen, Outi Elomaa, Juha Kere, Ulpu Saarialho-Kere, Tiina Jahkola, Kati Pääkkönen
Publikováno v:
Journal of Investigative Dermatology. 115:778-787
Stromelysin-2 is a matrix metalloproteinase that degrades in vitro several protein components relevant to wound repair such as collagens III and IV, gelatin, nidogen, laminin-1, proteoglycans, and elastin. Furthermore, it can activate other matrix me
Autor:
Maarit Vaalamo, Taina Hasan, Riikka Raudasoja, Leila Jeskanen, Erja Kerkelä, Ulpu Saarialho-Kere, Annamari Ranki, Aarne Oikarinen, Richard A. Pierce, Barry Starcher
Publikováno v:
Journal of Investigative Dermatology. 113(4):664-672
Photodamage is characterized by degradation of collagen and accumulation of abnormal elastin in the superficial dermis and several matrix metalloproteinases have previously been implicated in this process. Using immunohistochemistry and in situ hybri
Autor:
Kaisa Lehti, Ulpu Saarialho-Kere, Jorma Keski-Oja, Arja-Leena Kariniemi, Karonen T, Kristiina Airola, Jouko Lohi, Maarit Vaalamo
Publikováno v:
Karolinska Institutet
British Journal of Cancer
British Journal of Cancer
Since proteolysis of the dermal collagenous matrix and basement membranes is required for local invasive growth and early metastasis formation of cutaneous melanomas, we have analysed the activities/expression levels of certain metalloproteinases in
Autor:
Marja-Liisa Karjalainen-Lindsberg, Nina Johansson, Ulpu Saarialho-Kere, Maarit Vaalamo, Arja-Leena Kariniemi, Veli-Matti Kähäri, Laura Mattila
Publikováno v:
Journal of Investigative Dermatology. 109:96-101
Proteolysis is an intrinsic component of cutaneous wound repair and several matrix metalloproteinases have been shown to participate in various stages of this process. Therefore, we investigated the expression of a novel metalloproteinase, collagenas
Autor:
J. Lauharanta, Juha Kere, Ulpu Saarialho-Kere, Maarit Vaalamo, Pia Saarinen, Pauli Puolakkainen, M Weckroth
Publikováno v:
British Journal of Dermatology. 135:52-59
The present study was carried out to characterize the patterns of expression of matrix metalloproteinases or their tissue inhibitor (TIMP-1) in normally healing, acute vs. chronic, skin wounds. In situ hybridization was performed to localize collagen
Autor:
Maarit Vaalamo, Ulpu Saarialho-Kere, Kristiina Airola, Kirsti-Maria Niemi, Aarne Oikarinen, William C. Parks
Publikováno v:
Journal of Investigative Dermatology. 104(6):982-988
Migrating keratinocytes actively involved in reepithelialization in dermal wounds acquire a collagenolytic phenotype upon contact with the dermal matrix. To determine whether this phenotype is associated with repair in other forms of wounds, we asses
Publikováno v:
Human pathology. 30(7)
Wound healing is characterized by hemostasis, re-epithelialization, granulation tissue formation, and remodeling of the extracellular matrix. Matrix metalloproteinases and their specific inhibitors, TIMPs, contribute to these events. We investigated
Publikováno v:
The Journal of investigative dermatology. 112(4)
Accumulation of inflammatory cells such as macrophages may lead to degeneration of connective tissue matrix in various skin diseases. Macrophage metalloelastase, is a matrix metalloproteinase (MMP-12) capable of degrading elastin as well as various b
Autor:
Ulpu Saarialho-Kere, Seija Grénman, Veli-Matti Kähäri, Sakari Hietanen, Maarit Vaalamo, Nina Johansson, Pekka J. Klemi
Collagenase-3 (MMP-13) is a human matrix metalloproteinase specifically expressed by invading tumor cells in squamous cell carcinomas (SCCs) of the head and neck. Here, we have further elucidated the role of MMP-13 in tumor invasion by examining its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efbec2a80cacb200722b6fc71df14501
https://europepmc.org/articles/PMC1849989/
https://europepmc.org/articles/PMC1849989/
Publikováno v:
The Journal of investigative dermatology. 105(2)
Because dermatitis herpetiformis is characterized by neutrophilic inflammation and destructive changes in the basement membrane zone, we studied the in situ expression of interstitial collagenase and stromelysin-1 in 11 lesions. A prominent signal fo