Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Maarit Hellman"'
Autor:
Maria Kaukonen, Sean Woods, Saija Ahonen, Seppo Lemberg, Maarit Hellman, Marjo K. Hytönen, Perttu Permi, Tom Glaser, Hannes Lohi
Publikováno v:
Cell Reports, Vol 23, Iss 9, Pp 2643-2652 (2018)
Maternally skewed transmission of traits has been associated with genomic imprinting and oocyte-derived mRNA. We report canine congenital eye malformations, caused by an amino acid deletion (K12del) near the N terminus of retinol-binding protein (RBP
Externí odkaz:
https://doaj.org/article/19030cb9d7154372b571c14092bec77c
Autor:
Jonne Seppälä, Rafael C. Bernardi, Tatu J. K. Haataja, Maarit Hellman, Olli T. Pentikäinen, Klaus Schulten, Perttu Permi, Jari Ylänne, Ulla Pentikäinen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Cells’ ability to sense mechanical cues in their environment is crucial for fundamental cellular processes, leading defects in mechanosensing to be linked to many diseases. The actin cross-linking protein Filamin has an important role in t
Externí odkaz:
https://doaj.org/article/19baf53cadc947c297dabc4e0149c6e8
Autor:
Alexey Shapiguzov, Julia P Vainonen, Kerri Hunter, Helena Tossavainen, Arjun Tiwari, Sari Järvi, Maarit Hellman, Fayezeh Aarabi, Saleh Alseekh, Brecht Wybouw, Katrien Van Der Kelen, Lauri Nikkanen, Julia Krasensky-Wrzaczek, Nina Sipari, Markku Keinänen, Esa Tyystjärvi, Eevi Rintamäki, Bert De Rybel, Jarkko Salojärvi, Frank Van Breusegem, Alisdair R Fernie, Mikael Brosché, Perttu Permi, Eva-Mari Aro, Michael Wrzaczek, Jaakko Kangasjärvi
Publikováno v:
eLife, Vol 8 (2019)
Reactive oxygen species (ROS)-dependent signaling pathways from chloroplasts and mitochondria merge at the nuclear protein RADICAL-INDUCED CELL DEATH1 (RCD1). RCD1 interacts in vivo and suppresses the activity of the transcription factors ANAC013 and
Externí odkaz:
https://doaj.org/article/11587072b66843dd80d9ad5ae2e72b25
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e26633 (2011)
BACKGROUND: The Cancer-Testis antigens (CTA) are proteins expressed in human germ line and certain cancer cells. CTAs form a large gene family, representing 10% of X-chromosomal genes. They have high potential for cancer-specific immunotherapy. Howev
Externí odkaz:
https://doaj.org/article/9b540891e482481f9cb6ee7f44f9aa84
Publikováno v:
Expert Opinion on Therapeutic Targets
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Introduction: Enteroviruses are common viruses causing a huge number of acute and chronic infections and producing towering economic costs. Similarly, coronaviruses cause seasonal mild infections, epidemics, and even pandemics and can lead to severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8f9120bc28eeb5b7c9baeee59ebd1d
https://doi.org/10.1080/14728222.2021.1952985
https://doi.org/10.1080/14728222.2021.1952985
Autor:
Helena Tossavainen, Hasan Uğurlu, Mikael Karjalainen, Maarit Hellman, Lina Antenucci, Riku Fagerlund, Kalle Saksela, Perttu Permi
Class I SH3 domain-binding motifs generally comply with the consensus sequence [R/K]x0PxxP, the hydrophobic residue 0 being proline or leucine. We have studied the unusual 0 = Ala-specificity of SNX9 SH3 by determining its complex structure with a pe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0db7f8e0919c02f066884eeaeb7d775
http://hdl.handle.net/10138/346308
http://hdl.handle.net/10138/346308
Publikováno v:
Biomolecular Nmr Assignments
LEE-encoded effector EspF (EspF) is an effector protein part of enteropathogenic Escherichia coli’s (EPEC’s) arsenal for intestinal infection. This intrinsically disordered protein contains three highly conserved repeats which together compose ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21985fc08f4b494c9c5bd6521daec3bd
http://europepmc.org/articles/PMC7973643
http://europepmc.org/articles/PMC7973643
Publikováno v:
Journal of Biomolecular NMR. 74:147-159
Resonance assignment of intrinsically disordered proteins is remarkably challenging due to scant chemical shift dispersion arising from conformational heterogeneity. The challenge is even greater if repeating segments are present in the amino acid se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36a904252feb222e1412705eb2a62fc
https://doi.org/10.1007/s10858-020-00299-w
https://doi.org/10.1007/s10858-020-00299-w
Autor:
Vera Kovaleva, Richard Zimmermann, Mart Saarma, Maarit Hellman, Li-Ying Yu, Helka Göös, Päivi Lindholm, Perttu Permi, Ave Eesmaa, Kristofer Nõges, Martin Jung, Markku Varjosalo
Publikováno v:
Journal of Biological Chemistry
The Journal of Biological Chemistry
The Journal of Biological Chemistry
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-stress-regulated protein exhibiting cytoprotective properties through a poorly understood mechanism in various in vitro and in vivo models of neuronal and non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::313ba32ad4a5ccd78db57615fd60c668
http://urn.fi/URN:NBN:fi:jyu-202102221722
http://urn.fi/URN:NBN:fi:jyu-202102221722
Publikováno v:
Journal of Biomolecular Nmr
Unidirectional coherence transfer is highly efficient in intrinsically disordered proteins (IDPs). Their elevated ps-ns timescale dynamics ensures long transverse (T2) relaxation times allowing sophisticated coherence transfer pathway selection in co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6620f1056e7acba01ef5a5496070585e
https://pubmed.ncbi.nlm.nih.gov/33118136
https://pubmed.ncbi.nlm.nih.gov/33118136