Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Maaike Kockx"'
Autor:
Glen P. Lockwood, Nicholas J. Hunt, Maaike Kockx, Sun Woo Sophie Kang, David G. Le Couteur, Victoria C. Cogger
Publikováno v:
Livers, Vol 4, Iss 2, Pp 253-267 (2024)
The clearance of peripheral beta amyloid (Aβ) is a potential target for the treatment of Alzheimer’s disease (AD). The liver has been implicated in the elimination of Aβ from the peripheral circulation. Here, the single-pass uptake of Aβ40 in pe
Externí odkaz:
https://doaj.org/article/806bbeb6b8204766ad27b1ec7abc3583
Autor:
Jeffrey Wang, Maaike Kockx, Magdalena Bolek, Tim Lambert, David Sullivan, Vincent Chow, Leonard Kritharides
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 7, Pp 100577- (2024)
Patients with schizophrenia show a disproportionally increased risk of cardiovascular disease. Hypertriglyceridemia is prevalent in this population; however, how this relates to levels of remnant cholesterol, triglyceride (TG)-rich lipoprotein (TRL)
Externí odkaz:
https://doaj.org/article/2c9dfd5679924d67b0d29e7e1ffd5560
Publikováno v:
Atherosclerosis Plus, Vol 48, Iss , Pp 12-19 (2022)
Background and aims: Preeclampsia (PE) is associated with life-long increased risk of cardiovascular disease. One of the main protective functions of high-density lipoprotein (HDL) is its role in reverse cholesterol transport. HDL-mediated cholestero
Externí odkaz:
https://doaj.org/article/b936d1d76a464a6fa05c082ac9233b60
Autor:
Siân P. Cartland, Scott W. Genner, Gonzalo J. Martínez, Stacy Robertson, Maaike Kockx, Ruby CY. Lin, John F. O'Sullivan, Yen Chin Koay, Pradeep Manuneedhi Cholan, Melkam A. Kebede, Andrew J. Murphy, Seth Masters, Martin R. Bennett, Wendy Jessup, Leonard Kritharides, Carolyn Geczy, Sanjay Patel, Mary M. Kavurma
Publikováno v:
iScience, Vol 12, Iss , Pp 41-52 (2019)
Summary: Circulating tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) levels are reduced in patients with cardiovascular disease, and TRAIL gene deletion in mice exacerbates atherosclerosis and inflammation. How TRAIL protects ag
Externí odkaz:
https://doaj.org/article/c7ca2592d76c4f63b979d841c5be347e
Autor:
Ingrid C. Gelissen, Laura J. Sharpe, Cecilia Sandoval, Geetha Rao, Maaike Kockx, Leonard Kritharides, Wendy Jessup, Andrew J. Brown
Publikováno v:
Journal of Lipid Research, Vol 53, Iss 10, Pp 2133-2140 (2012)
ABCG1 is an ABC half-transporter that exports cholesterol from cells to HDL. This study set out to investigate differences in posttranslational processing of two human ABCG1 protein isoforms, termed ABCG1(+12) and ABCG1(− 12), that differ by the pr
Externí odkaz:
https://doaj.org/article/c990d1183fe34e0abe873d41cfb2cd10
Autor:
Sue M. Liu, Anne Cogny, Maaike Kockx, Roger T. Dean, Katharina Gaus, Wendy Jessup, Leonard Kritharides
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 6, Pp 1156-1166 (2003)
Human monocyte-derived foam cell macrophages (HMFCs) are resistant to cholesterol efflux mediated by physiological acceptors. The role of the plasma membrane in regulating depletion of free cholesterol (FC) and of cholesteryl ester (CE) was investiga
Externí odkaz:
https://doaj.org/article/9bd17d81fbaf4aabb081acaea59d78d2
Autor:
Maaike Kockx, Denuja Karunakaran, Mathew Traini, Jing Xue, Kuan Yen Huang, Diana Nawara, Katharina Gaus, Wendy Jessup, Phillip J Robinson, Leonard Kritharides
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111186 (2014)
Dynamins are fission proteins that mediate endocytic and exocytic membrane events and are pharmacological therapeutic targets. These studies investigate whether dynamin II regulates constitutive protein secretion and show for the first time that phar
Externí odkaz:
https://doaj.org/article/10dd734f603c4905a989bc5ff4f243db
Autor:
Estella Sanchez-Guerrero, Elya Chen, Maaike Kockx, Si-Wei An, Beng H. Chong, Levon M. Khachigian
Publikováno v:
PLoS ONE, Vol 8, Iss 12 (2013)
Externí odkaz:
https://doaj.org/article/d0f8fa9fcf864364a3a9f2235a441007
Autor:
Estella Sanchez-Guerrero, Elya Chen, Maaike Kockx, Si-Wei An, Beng H Chong, Levon M Khachigian
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e39811 (2012)
The immediate-early gene Egr-1 controls the inducible expression of many genes implicated in the pathogenesis of a range of vascular disorders, yet our understanding of the mechanisms controlling the rapid expression of this prototypic zinc finger tr
Externí odkaz:
https://doaj.org/article/63963c9878274f558365d0ed29b4d136
Autor:
Bikash Manandhar, Elvis Pandzic, Nandan Deshpande, Sing-Young Chen, Valerie Wasinger, Maaike Kockx, Elias Glaros, Kwok Leung Ong, Shane R. Thomas, Marc R. Wilkins, Renee M. Whan, Blake J. Cochran, Kerry-Anne Rye
Objective:High cholesterol levels in pancreatic β-cells cause oxidative stress and decrease insulin secretion. β-cells can internalize apolipoprotein (apo) A-I, which increases insulin secretion. This study asks whether internalization of apoA-I im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71940cb463272863273b924c9e868188
https://doi.org/10.1101/2023.04.03.535492
https://doi.org/10.1101/2023.04.03.535492
