Zobrazeno 1 - 10
of 1 804
pro vyhledávání: '"Maagdenberg A"'
Autor:
Helle W. van den Maagdenberg, Martin Šícho, David Alencar Araripe, Sohvi Luukkonen, Linde Schoenmaker, Michiel Jespers, Olivier J. M. Béquignon, Marina Gorostiola González, Remco L. van den Broek, Andrius Bernatavicius, J. G. Coen van Hasselt, Piet. H. van der Graaf, Gerard J. P. van Westen
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-16 (2024)
Abstract Building reliable and robust quantitative structure–property relationship (QSPR) models is a challenging task. First, the experimental data needs to be obtained, analyzed and curated. Second, the number of available methods is continuously
Externí odkaz:
https://doaj.org/article/9debc1b05a614b88bc3be65b20d3adda
Autor:
Nico A. Jansen, Chelsey Linnenbank, Maarten Schenke, Rob A. Voskuyl, Maria S. Jorge, Georgii Krivoshein, Cor Breukel, Margot M. Linssen, Jill W.C. Claassens, Conny Brouwers, Sandra H. van Heiningen, Anders Heuck, Karin Lykke-Hartmann, Else A. Tolner, Arn M.J.M. van den Maagdenberg
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106714- (2024)
The mechanisms of initiation of spreading depolarization (SD) are understudied due to a paucity of disease models with spontaneously occurring events. We here present a novel mouse model of familial hemiplegic migraine type 2 (FHM2), expressing the m
Externí odkaz:
https://doaj.org/article/06ea3f35c9c3417aa35517e998fb1500
Autor:
Daniele Bizzarri, Marcel J.T. Reinders, Lieke Kuiper, Marian Beekman, Joris Deelen, Joyce B.J. van Meurs, Jenny van Dongen, René Pool, Dorret I. Boomsma, Mohsen Ghanbari, Lude Franke, Pieternella E. Slagboom, Erik B. van den Akker, J.M. Geleijnse, E. Boersma, W.E. van Spil, M.M.J. van Greevenbroek, C.D.A. Stehouwer, C.J.H. van der Kallen, I.C.W. Arts, F. Rutters, J.W.J. Beulens, M. Muilwijk, P.J.M. Elders, L.M. 't Hart, M. Ghanbari, M.A. Ikram, M.G. Netea, M. Kloppenburg, Y.F.M. Ramos, N. Bomer, I. Meulenbelt, K. Stronks, M.B. Snijder, A.H. Zwinderman, B.T. Heijmans, L.H. Lumey, C. Wijmenga, J. Fu, A. Zhernakova, J. Deelen, S.P. Mooijaart, M. Beekman, P.E. Slagboom, G.L.J. Onderwater, A.M.J.M. van den Maagdenberg, G.M. Terwindt, C. Thesing, M. Bot, B.W.J.H. Penninx, S. Trompet, J.W. Jukema, N. Sattar, I.C.C. van der Horst, P. van der Harst, C. So-Osman, J.A. van Hilten, R.G.H.H. Nelissen, I.E. Höfer, F.W. Asselbergs, P. Scheltens, C.E. Teunissen, W.M. van der Flier, J. van Dongen, R. Pool, A.H.M. Willemsen, D.I. Boomsma, H.E.D. Suchiman, J.J.H. Barkey Wolf, D. Cats, H. Mei, M. Slofstra, M. Swertz, M.J.T. Reinders, E.B. van den Akker
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105279- (2024)
Summary: Background: 1H-NMR metabolomics and DNA methylation in blood are widely known biomarkers predicting age-related physiological decline and mortality yet exert mutually independent mortality and frailty signals. Methods: Leveraging multi-omics
Externí odkaz:
https://doaj.org/article/dd2f1125885a4ef2be328f0b36ea785b
Autor:
van den Maagdenberg, Helle W.1 (AUTHOR), Šícho, Martin1,2 (AUTHOR), Araripe, David Alencar1,3 (AUTHOR), Luukkonen, Sohvi1,4 (AUTHOR), Schoenmaker, Linde1 (AUTHOR), Jespers, Michiel1 (AUTHOR), Béquignon, Olivier J. M.1,5 (AUTHOR), González, Marina Gorostiola1,6 (AUTHOR), van den Broek, Remco L.1 (AUTHOR), Bernatavicius, Andrius1,7 (AUTHOR), van Hasselt, J. G. Coen1 (AUTHOR), van der Graaf, Piet. H.1,8 (AUTHOR), van Westen, Gerard J. P.1 (AUTHOR) gerard@lacdr.leidenuniv.nl
Publikováno v:
Journal of Cheminformatics. 11/14/2024, Vol. 16 Issue 1, p1-16. 16p.
Autor:
Jansen, Nico A., Linnenbank, Chelsey, Schenke, Maarten, Voskuyl, Rob A., Jorge, Maria S., Krivoshein, Georgii, Breukel, Cor, Linssen, Margot M., Claassens, Jill W.C., Brouwers, Conny, van Heiningen, Sandra H., Heuck, Anders, Lykke-Hartmann, Karin, Tolner, Else A., van den Maagdenberg, Arn M.J.M.
Publikováno v:
In Neurobiology of Disease November 2024 202
Autor:
Geleijnse, J.M., Boersma, E., van Spil, W.E., van Greevenbroek, M.M.J., Stehouwer, C.D.A., van der Kallen, C.J.H., Arts, I.C.W., Rutters, F., Beulens, J.W.J., Muilwijk, M., Elders, P.J.M., 't Hart, L.M., Ghanbari, M., Ikram, M.A., Netea, M.G., Kloppenburg, M., Ramos, Y.F.M., Bomer, N., Meulenbelt, I., Stronks, K., Snijder, M.B., Zwinderman, A.H., Heijmans, B.T., Lumey, L.H., Wijmenga, C., Fu, J., Zhernakova, A., Deelen, J., Mooijaart, S.P., Beekman, M., Slagboom, P.E., Onderwater, G.L.J., van den Maagdenberg, A.M.J.M., Terwindt, G.M., Thesing, C., Bot, M., Penninx, B.W.J.H., Trompet, S., Jukema, J.W., Sattar, N., van der Horst, I.C.C., van der Harst, P., So-Osman, C., van Hilten, J.A., Nelissen, R.G.H.H., Höfer, I.E., Asselbergs, F.W., Scheltens, P., Teunissen, C.E., van der Flier, W.M., van Dongen, J., Pool, R., Willemsen, A.H.M., Boomsma, D.I., Suchiman, H.E.D., Barkey Wolf, J.J.H., Cats, D., Mei, H., Slofstra, M., Swertz, M., Reinders, M.J.T., van den Akker, E.B., Bizzarri, Daniele, Reinders, Marcel J.T., Kuiper, Lieke, Beekman, Marian, Deelen, Joris, van Meurs, Joyce B.J., van Dongen, Jenny, Pool, René, Boomsma, Dorret I., Ghanbari, Mohsen, Franke, Lude, Slagboom, Pieternella E., van den Akker, Erik B.
Publikováno v:
In eBioMedicine September 2024 107
Autor:
Divya Mehta, Irene de Boer, Heidi G. Sutherland, Judith A. Pijpers, Charlene Bron, Charlotte Bainomugisa, Larisa M. Haupt, Arn M. J. M. van den Maagdenberg, Lyn R. Griffiths, Dale R. Nyholt, Gisela M. Terwindt
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-12 (2023)
Abstract Background Chronic migraine, a highly disabling migraine subtype, affects nearly 2% of the general population. Understanding migraine chronification is vital for developing better treatment and prevention strategies. An important factor in t
Externí odkaz:
https://doaj.org/article/733e0f66098746629b8059295d7d35d8
Autor:
Gefferie, Silvano R., Ossenblok, Pauly P.W., Dietze, Christoph S., Sargsyan, Armen, Bourez-Swart, Mireille, van den Maagdenberg, Arn M.J.M., Thijs, Roland D.
Publikováno v:
In Epilepsy Research August 2024 204
Autor:
Guanglu Li, Shaojie Duan, International Headache Genetics Consortium (IHGC), Tao Zheng, Tiantian Zhu, Baoquan Qu, Lei Liu, Zunjing Liu, Verneri Anttila, Ville Artto, Andrea C Belin, Anna Bjornsdottir, Gyda Bjornsdottir, Dorret I Boomsma, Sigrid Børte, Mona A Chalmer, Daniel I Chasman, Bru Cormand, Ester Cuenca-Leon, George Davey-Smith, Irene de Boer, Martin Dichgans, Tonu Esko, Tobias Freilinger, Padhraig Gormley, Lyn R Griffiths, Eija Hämäläinen, Thomas F Hansen, Aster VE Harder, Heidi Hautakangas, Marjo Hiekkala, Maria G Hrafnsdottir, M. Arfan Ikram, Marjo-Riitta Järvelin, Risto Kajanne, Mikko Kallela, Jaakko Kaprio, Mari Kaunisto, Lisette JA Kogelman, Espen S Kristoffersen, Christian Kubisch, Mitja Kurki, Tobias Kurth, Lenore Launer, Terho Lehtimäki, Davor Lessel, Lannie Ligthart, Sigurdur H Magnusson, Rainer Malik, Bertram Müller-Myhsok, Carrie Northover, Dale R Nyholt, Jes Olesen, Aarno Palotie, Priit Palta, Linda M Pedersen, Nancy Pedersen, Matti Pirinen, Danielle Posthuma, Patricia Pozo-Rosich, Alice Pressman, Olli Raitakari, Caroline Ran, Gudrun R Sigurdardottir, Hreinn Stefansson, Kari Stefansson, Olafur A Sveinsson, Gisela M Terwindt, Thorgeir E Thorgeirsson, Arn MJM vanden Maagdenberg, Cornelia van Duijn, Maija Wessman, Bendik S Winsvold, John-Anker Zwart.
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMigraine has an increased prevalence in several immune disorders, but genetic cause-effect relationships remain unclear. Mendelian randomization (MR) was used in this study to explore whether immune diseases are causally associated with mig
Externí odkaz:
https://doaj.org/article/a30f6c7b567e43149a0c5afd66373445
Autor:
Inge C.M. Loonen, Rob A. Voskuyl, Maarten Schenke, Sandra H. van Heiningen, Arn M.J.M. van den Maagdenberg, Else A. Tolner
Publikováno v:
Neurobiology of Disease, Vol 192, Iss , Pp 106405- (2024)
Mechanisms underlying the migraine aura are incompletely understood, which to large extent is related to a lack of models in which cortical spreading depolarization (CSD), the correlate of the aura, occurs spontaneously. Here, we investigated electro
Externí odkaz:
https://doaj.org/article/9e67dc8de7124b71a22deed24cfd3004