Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Maagdenberg, A. van den"'
Publikováno v:
Neuroinformatics. HUMANA PRESS INC
Neuroinformatics
Neuroinformatics, 20(4), 1077-1092. Humana Press
Neuroinformatics
Neuroinformatics, 20(4), 1077-1092. Humana Press
Functional assessment of in vitro neuronal networks—of relevance for disease modelling and drug testing—can be performed using multi-electrode array (MEA) technology. However, the handling and processing of the large amount of data typically gene
Publikováno v:
Current Opinion in Structural Biology, 79:102537
The factors determining a drug's success are manifold, making de novo drug design an inherently multi-objective optimisation (MOO) problem. With the advent of machine learning and optimisation methods, the field of multi-objective compound design has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ffc116cdcc822f38ca7358832521a01
http://hdl.handle.net/1887/3590043
http://hdl.handle.net/1887/3590043
Autor:
Krivoshein, G., Bakreen, A., Maagdenberg, A.M.J.M. van den, Malm, T., Giniatullin, R., Jolkkonen, J.
Publikováno v:
International Journal of Molecular Sciences, 23(20). MDPI
Stroke can be followed by immediate severe headaches. As headaches are initiated by the activation of trigeminal meningeal afferents, we assessed changes in the activity of meningeal afferents in mice subjected to cortical photothrombosis. Cortical p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a1581732207347245c9c46f58db6976c
http://hdl.handle.net/1887/3502227
http://hdl.handle.net/1887/3502227
Autor:
He, B.S., Di, X., Gulded, F., Harder, A.V.E., Maagdenberg, A.M.J.M. van den, Terwindt, G.M., Krekels, E.H.J., Kohler, I., Harms, A.C., Ramautar, R., Hankemeier, T.
Publikováno v:
Analytica Chimica Acta, 1210:339888, 1-9. Elsevier
Analytica Chimica Acta, 1210:339888. ELSEVIER
Analytica Chimica Acta, 1210, 339888. Elsevier {BV}
He, B, Di, X, Guled, F, Harder, A V E, van den Maagdenberg, A M J M, Terwindt, G M, Krekels, E H J, Kohler, I, Harms, A, Ramautar, R & Hankemeier, T 2022, ' Quantification of endocannabinoids in human cerebrospinal fluid using a novel micro-flow liquid chromatography-mass spectrometry method ', Analytica Chimica Acta, vol. 1210, 339888, pp. 1-9 . https://doi.org/10.1016/j.aca.2022.339888
Analytica Chimica Acta, 1210:339888. ELSEVIER
Analytica Chimica Acta, 1210, 339888. Elsevier {BV}
He, B, Di, X, Guled, F, Harder, A V E, van den Maagdenberg, A M J M, Terwindt, G M, Krekels, E H J, Kohler, I, Harms, A, Ramautar, R & Hankemeier, T 2022, ' Quantification of endocannabinoids in human cerebrospinal fluid using a novel micro-flow liquid chromatography-mass spectrometry method ', Analytica Chimica Acta, vol. 1210, 339888, pp. 1-9 . https://doi.org/10.1016/j.aca.2022.339888
The endocannabinoid system (ECS) is implicated in various brain disorders. Changes in the composition of the cerebrospinal fluid (CSF) may be associated with ECS-related pathologies. Endocannabinoids (eCBs) and their analogues are present at low conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596e312038584042c1eef1ac3d68faf4
https://research.vu.nl/en/publications/f49eca75-4f47-4b7b-b899-26747643b10b
https://research.vu.nl/en/publications/f49eca75-4f47-4b7b-b899-26747643b10b
Autor:
Terpollili, N.A., Dolp, R., Waehner, K., Schwarzmaier, S.M., Rumbler, E., Todorov, B., Ferrari, M.D., Maagdenberg, A.M.J.M. van den, Plesnila, N.
Publikováno v:
eLife, 11. eLIFE SCIENCES PUBL LTD
Patients suffering from familial hemiplegic migraine type 1 (FHM1) may have a disproportionally severe outcome after head trauma, but the underlying mechanisms are unclear. Hence, we subjected knock-in mice carrying the severer S218L or milder R192Q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8abb633c22a30945e664a6e2f941fd
https://hdl.handle.net/1887/3502228
https://hdl.handle.net/1887/3502228
Autor:
Hautakangas, H., Winsvold, B.S., Ruotsalainen, S.E., Bjornsdottir, G., Harder, A.V.E., Kogelman, L.J.A., Thomas, L.F., Noordam, R., Benner, C., Gormley, P., Artto, V., Banasik, K., Bjornsdottir, A., Boomsma, D.I., Brumpton, B., Burgdorf, K.S., Buring, J.E., Chalmer, M.A., Boer, I. de, Dichgans, M., Erikstrup, C., Farkkila, M., Garbrielsen, M.E., Ghanbari, M., Hagen, K., Happola, P., Hottenga, J.J., Hrafnsdottir, M.G., Hveem, K., Johnsen, M.B., Kahonen, M., Kristoffersen, E.S., Kurth, T., Lehtimaki, T., Lighart, L., Magnusson, S.H., Malik, R., Pedersen, O.B., Pelzer, N., Penninx, B.W.J.H., Ran, C., Ridker, P.M., Rosendaal, F.R., Sigurdardottir, G.R., Skogholt, A.H., Sveinsson, O.A., Thorgeirsson, T.E., Ullum, H., Vijfhuizen, L.S., Widen, E., Dijk, K.W. van, Aromaa, A., Belin, A.C., Freilinger, T., Ikram, M.A., Jarvelin, M.R., Raitakari, O.T., Terwindt, G.M., Kallela, M., Wessman, M., Olesen, J., Chasman, D.I., Nyholt, D.R., Stefansson, H., Stefansson, K., Maagdenberg, A.M.J.M. van den, Hansen, T.F., Ripatti, S., Zwart, J.A., Palotie, A., Pirinen, M., Int Headache Genetics Consortium, HUNT All-in Headache, Danish Blood Donor Study Genomic C
Publikováno v:
Nature genetics, 54(2), 152-160. Nature Publishing Group
Nature Genetics
International Headache Genetics Consortium, HUNT All-in Headache & Danish Blood Donor Study Genomic Cohort 2022, ' Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles ', Nature Genetics, vol. 54, no. 2, pp. 152-160 . https://doi.org/10.1038/s41588-021-00990-0
Nature Genetics, 54, 152-160. NATURE PORTFOLIO
Hautakangas, H, Winsvold, B S, Ruotsalainen, S E, Bjornsdottir, G, Harder, A V E, Kogelman, L J A, Thomas, L F, Noordam, R, Benner, C, Gormley, P, Artto, V, Banasik, K, Bjornsdottir, A, Boomsma, D I, Brumpton, B M, Burgdorf, K S, Buring, J E, Chalmer, M A, de Boer, I, Dichgans, M, Erikstrup, C, Farkkila, M, Garbrielsen, M E, Ghanbari, M, Hagen, K, Happola, P, Hottenga, J-J, Hrafnsdottir, M G, Hveem, K, Johnsen, M B, Kahonen, M, Kristoffersen, E S, Kurth, T, Lehtimaki, T, Lighart, L, Magnusson, S H, Malik, R, Pedersen, O B, Pelzer, N, Penninx, B W J H, Ran, C, Ridker, P M, Rosendaal, F R, Sigurdardottir, G R, Skogholt, A H, Sveinsson, O A, Thorgeirsson, T E, Ullum, H, Vijfhuizen, L S, Widen, E, van Dijk, K W, Aromaa, A, Belin, A C, Freilinger, T, Ikram, M A, Jarvelin, M-R, Raitakari, O T, Terwindt, G M, Kallela, M, Wessman, M, Olesen, J, Chasman, D I, Nyholt, D R, Stefansson, H, Stefansson, K, van den Maagdenberg, A M J M, Hansen, T F, Ripatti, S, Zwart, J-A, Palotie, A & Pirinen, M 2022, ' Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles ', Nature Genetics, vol. 54, pp. 152-160 . https://doi.org/10.1038/s41588-021-00990-0
Hautakangas, H, Winsvold, B S, Ruotsalainen, S E, Bjornsdottir, G, Harder, A V E, Kogelman, L J A, Thomas, L F, Noordam, R, Benner, C, Gormley, P, Artto, V, Banasik, K, Bjornsdottir, A, Boomsma, D I, Brumpton, B M, Burgdorf, K S, Buring, J E, Chalmer, M A, de Boer, I, Dichgans, M, Erikstrup, C, Färkkilä, M, Garbrielsen, M E, Ghanbari, M, Hagen, K, Häppölä, P, Hottenga, J J, Hrafnsdottir, M G, Hveem, K, Johnsen, M B, Kähönen, M, Kristoffersen, E S, Kurth, T, Lehtimäki, T, Lighart, L, Magnusson, S H, Malik, R, Pedersen, O B, Pelzer, N, Penninx, B W J H, Ran, C, Ridker, P M, Rosendaal, F R, Sigurdardottir, G R, Skogholt, A H, Sveinsson, O A, Thorgeirsson, T E, Ullum, H, Vijfhuizen, L S, Widen, E, van Dijk, K W, International Headache Genetics Consortium, HUNT All-in Headache, Danish Blood Donor Study Genomic Cohort, Aromaa, A, Belin, A C, Freilinger, T, Ikram, M A, Järvelin, M-R, Raitakari, O T, Terwindt, G M, Kallela, M, Wessman, M, Olesen, J, Chasman, D I, Nyholt, D R, Stefansson, H, Stefansson, K, van den Maagdenberg, A M J M, Hansen, T F, Ripatti, S, Zwart, J-A, Palotie, A & Pirinen, M 2022, ' Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles ', Nature Genetics, vol. 54, no. 2, pp. 152-160 . https://doi.org/10.1038/s41588-021-00990-0
Nature Genetics, 54(2), 152-160. Nature Publishing Group
Hautakangas, H, Winsvold, B S, Boomsma, D I, Hottenga, J-J, Ligthart, L, Penninx, B W J H, Palotie, A, Pirinen, M & International Headache Genetics Consortium 2022, ' Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles ', Nature genetics, vol. 54, no. 2, pp. 152-160 . https://doi.org/10.1038/s41588-021-00990-0
Nature Genetics
International Headache Genetics Consortium, HUNT All-in Headache & Danish Blood Donor Study Genomic Cohort 2022, ' Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles ', Nature Genetics, vol. 54, no. 2, pp. 152-160 . https://doi.org/10.1038/s41588-021-00990-0
Nature Genetics, 54, 152-160. NATURE PORTFOLIO
Hautakangas, H, Winsvold, B S, Ruotsalainen, S E, Bjornsdottir, G, Harder, A V E, Kogelman, L J A, Thomas, L F, Noordam, R, Benner, C, Gormley, P, Artto, V, Banasik, K, Bjornsdottir, A, Boomsma, D I, Brumpton, B M, Burgdorf, K S, Buring, J E, Chalmer, M A, de Boer, I, Dichgans, M, Erikstrup, C, Farkkila, M, Garbrielsen, M E, Ghanbari, M, Hagen, K, Happola, P, Hottenga, J-J, Hrafnsdottir, M G, Hveem, K, Johnsen, M B, Kahonen, M, Kristoffersen, E S, Kurth, T, Lehtimaki, T, Lighart, L, Magnusson, S H, Malik, R, Pedersen, O B, Pelzer, N, Penninx, B W J H, Ran, C, Ridker, P M, Rosendaal, F R, Sigurdardottir, G R, Skogholt, A H, Sveinsson, O A, Thorgeirsson, T E, Ullum, H, Vijfhuizen, L S, Widen, E, van Dijk, K W, Aromaa, A, Belin, A C, Freilinger, T, Ikram, M A, Jarvelin, M-R, Raitakari, O T, Terwindt, G M, Kallela, M, Wessman, M, Olesen, J, Chasman, D I, Nyholt, D R, Stefansson, H, Stefansson, K, van den Maagdenberg, A M J M, Hansen, T F, Ripatti, S, Zwart, J-A, Palotie, A & Pirinen, M 2022, ' Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles ', Nature Genetics, vol. 54, pp. 152-160 . https://doi.org/10.1038/s41588-021-00990-0
Hautakangas, H, Winsvold, B S, Ruotsalainen, S E, Bjornsdottir, G, Harder, A V E, Kogelman, L J A, Thomas, L F, Noordam, R, Benner, C, Gormley, P, Artto, V, Banasik, K, Bjornsdottir, A, Boomsma, D I, Brumpton, B M, Burgdorf, K S, Buring, J E, Chalmer, M A, de Boer, I, Dichgans, M, Erikstrup, C, Färkkilä, M, Garbrielsen, M E, Ghanbari, M, Hagen, K, Häppölä, P, Hottenga, J J, Hrafnsdottir, M G, Hveem, K, Johnsen, M B, Kähönen, M, Kristoffersen, E S, Kurth, T, Lehtimäki, T, Lighart, L, Magnusson, S H, Malik, R, Pedersen, O B, Pelzer, N, Penninx, B W J H, Ran, C, Ridker, P M, Rosendaal, F R, Sigurdardottir, G R, Skogholt, A H, Sveinsson, O A, Thorgeirsson, T E, Ullum, H, Vijfhuizen, L S, Widen, E, van Dijk, K W, International Headache Genetics Consortium, HUNT All-in Headache, Danish Blood Donor Study Genomic Cohort, Aromaa, A, Belin, A C, Freilinger, T, Ikram, M A, Järvelin, M-R, Raitakari, O T, Terwindt, G M, Kallela, M, Wessman, M, Olesen, J, Chasman, D I, Nyholt, D R, Stefansson, H, Stefansson, K, van den Maagdenberg, A M J M, Hansen, T F, Ripatti, S, Zwart, J-A, Palotie, A & Pirinen, M 2022, ' Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles ', Nature Genetics, vol. 54, no. 2, pp. 152-160 . https://doi.org/10.1038/s41588-021-00990-0
Nature Genetics, 54(2), 152-160. Nature Publishing Group
Hautakangas, H, Winsvold, B S, Boomsma, D I, Hottenga, J-J, Ligthart, L, Penninx, B W J H, Palotie, A, Pirinen, M & International Headache Genetics Consortium 2022, ' Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles ', Nature genetics, vol. 54, no. 2, pp. 152-160 . https://doi.org/10.1038/s41588-021-00990-0
Genome-wide association analyses identify 123 susceptibility loci for migraine and implicate neurovascular mechanisms in its pathophysiology. Subtype analyses highlight risk loci specific for migraine with or without aura in addition to shared risk v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::271e89f31a913a67875ee7088a9a1e7c
https://research.vu.nl/en/publications/dad00511-8fd1-468a-a806-7f8306e18447
https://research.vu.nl/en/publications/dad00511-8fd1-468a-a806-7f8306e18447
Autor:
Ferrari, M.D., Goadsby, P.J., Burstein, R., Kurth, T., Ayata, C., Charles, A., Ashina, M., Maagdenberg, A.M.J.M. van den, Dodick, D.W.
Migraine is a common headache disorder. This Primer by Ferrari and colleagues summarizes the epidemiology, pathophysiology, diagnosis and treatment of migraine. Moreover, quality of life issues faced by patients with migraine and future research aven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______202::ef532b8d419dd20be0ff09167615b7ab
https://hdl.handle.net/1887/3502231
https://hdl.handle.net/1887/3502231
Autor:
Ferrari, M.D., Goadsby, P.J., Burstein, R., Kurth, T., Ayata, C., Charles, A., Ashina, M., Maagdenberg, A.M.J.M. van den, Dodick, D.W.
Migraine is a common headache disorder. This Primer by Ferrari and colleagues summarizes the epidemiology, pathophysiology, diagnosis and treatment of migraine. Moreover, quality of life issues faced by patients with migraine and future research aven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10693::ef532b8d419dd20be0ff09167615b7ab
https://hdl.handle.net/1887/3502231
https://hdl.handle.net/1887/3502231
Autor:
Hagenbeek, F.A., Pool, R., Dongen, J. van, Draisma, H.M., Hottenga, J.J., Willemsen, G., Abdellaoui, A., Fedko, I.O., Braber, A. den, Visser, P.J., Geus, E.J.C.N. de, Duijn, C.M. van, Harms, A.C., Bartels, M., Nivard, M.G., Boomsma, D.I., Hankemeier, T., Beulens, J.W., Rutters, F., Flier, W.M. van der, Hart, L.M., Bom, J.A. van der, Kloppenburg, M., Harst, P. van der, Bomer, N., Hilten, J.A. van, So-Osman, C., Meessen, J.M.T.A., Fu, J., Wijmenga, C., Zhernikova, A., Slofstra, M., Swertz, M., Onderwater, G.L.J., Terwindt, G.M., Heijden, A.A.W.A. van der, Asselbergs, F.W., Boersma, E., Elders, P.M., Geleijnse, J.M., Ikram, M.A., Mooijaart, S.P., Nelissen, R.G.H.H., Netea, M.G., Penninx, B.W.J.H., Stehouwer, C.D.A., Kallen, C.J.H. van der, Greevenbroek, M.M.J. van, Teunissen, C.E., Maagdenberg, A.M.J.M. van den, Spil, W.E. van, Zwinderman, A.H., Jukema, J.W., Mei, H., Akker, E.B. van den, Deelen, J., Horst I.C.C. van der, Reinders M.J.T., Abdel Abdellaoui
Publikováno v:
Nature Communications, 11, 1702. NATURE PUBLISHING GROUP
Correction to: Nature Communications https://doi.org/10.1038/s41467-019-13770-6, published online 7 January 2020.The original version of the Supplementary Information associated with this Article included an incorrect Supplementary Data 1 file, in wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3e69e2a2c66141570440b4af060dced2
http://hdl.handle.net/1887/138365
http://hdl.handle.net/1887/138365