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C-H Cyanation of 6-Ring N-Containing Heteroaromatics

Autor: Elbert, BL, Farley, AJM, Gorman, TW, Johnson, TC, Genicot, C, Lallemand, B, Pasau, P, Flasz, J, Castro, JL, MacCoss, M, Paton, RS, Schofield, CJ, Smith, MD, Willis, MC, Dixon, DJ

Publikováno v: Chemistry (Weinheim an Der Bergstrasse, Germany)

Heteroaromatic nitriles are important compounds in drug discovery, both for their prevalence in the clinic and due to the diverse range of transformations they can undergo. As such, efficient and reliable methods to access them have the potential for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0ed5d58129c149622ba9384fab7b2339
https://pubmed.ncbi.nlm.nih.gov/28833674

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Comparative analysis of the transcriptome across distant species

Autor: Gerstein, MB, Rozowsky, J, Yan, KK, Wang, D, Cheng, C, Brown, JB, Davis, CA, Hillier, L, Sisu, C, Li, JJ, Pei, B, Harmanci, AO, Duff, MO, Djebali, S, Alexander, RP, Alver, BH, Auerbach, R, Bell, K, Bickel, PJ, Boeck, ME, Boley, NP, Booth, BW, Cherbas, L, Cherbas, P, Di, C, Dobin, A, Drenkow, J, Ewing, B, Fang, G, Fastuca, M, Feingold, EA, Frankish, A, Gao, G, Good, PJ, Guigó, R, Hammonds, A, Harrow, J, Hoskins, RA, Howald, C, Hu, L, Huang, H, Hubbard, TJP, Huynh, C, Jha, S, Kasper, D, Kato, M, Kaufman, TC, Kitchen, RR, Ladewig, E, Lagarde, J, Lai, E, Leng, J, Lu, Z, MacCoss, M, May, G, McWhirter, R, Merrihew, G, Miller, DM, Mortazavi, A, Murad, R, Oliver, B, Olson, S, Park, PJ, Pazin, MJ, Perrimon, N, Pervouchine, D, Reinke, V, Reymond, A, Robinson, G

Publikováno v: Gerstein, MB; Rozowsky, J; Yan, KK; Wang, D; Cheng, C; Brown, JB; et al.(2014). Comparative analysis of the transcriptome across distant species. Nature, 512(7515), 445-448. doi: 10.1038/nature13424. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/7w33f659

The transcriptome is the readout of the genome. Identifying common features in it across distant species can reveal fundamental principles. To this end, the ENCODE and modENCODE consortia have generated large amounts of matched RNA-sequencing data fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::3715f93c4e6a4bf38a0b9dfb59e10efc
http://www.escholarship.org/uc/item/7w33f659

EP6 Quantitative Proteomics

Autor: Wu, C. C., MacCoss, M., Washburn, M.

There are numerous approaches to study the proteome in a quantitative manner. All rely heavily on optimized sample preparation and appropriate statistical analysis of resulting datasets. This session will cover the following aspects of quantitative p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmc_________::8e928ddee2b9c5967a36e032d2648815
https://europepmc.org/articles/PMC2292016/