Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ma. Reina Improgo"'
Autor:
Jennifer R. Brown, Divya Chaudhary, Bethany Tesar, Haesook T. Kim, Stacey M. Fernandes, Reuma Magori-Cohen, Lijian Yu, William F. Westlin, Siddha Kasar, Kevin Hoang, Ma. Reina Improgo, Wenyan Miao, Josephine L. Klitgaard
Publikováno v:
British Journal of Haematology.
The L265P somatic mutation in the Myeloid Differentiation Primary Response 88 (MYD88) gene is a recurrent mutation in chronic lymphocytic leukaemia (CLL). This mutation has functional effects in various haematological malignancies but its role in CLL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd6220203b80bbed67ad8303952f94b
https://doi.org/10.1111/bjh.15714
https://doi.org/10.1111/bjh.15714
Autor:
Stacey M. Fernandes, Adam Kiezun, Catherine J. Wu, Samira Bahl, Eric S. Lander, Sandra Robrecht, Atanas Kamburov, Eugen Tausch, Esther Rheinbay, Haesook T. Kim, Dan-Avi Landau, Siddha Kasar, Ma. Reina Improgo, Grace Tiao, Jennifer R. Brown, Weijie Poh, Gad Getz, Kevin Hoang, Jasmin Bahlo, Amaro Taylor-Weiner, Stephan Stilgenbauer, Carrie Cibulskis, Kirsten Fischer, Stacey Gabriel, Michael Hallek
Publikováno v:
Leukemia
Chronic lymphocytic leukemia (CLL) is a highly heritable cancer, with a 7.5-fold increased risk in first-degree relatives.1 However, inherited predisposition to CLL remains largely unexplained by traditional linkage or genome-wide association studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e858bee9c00e9a55005b21604da437
https://pubmed.ncbi.nlm.nih.gov/28652578
https://pubmed.ncbi.nlm.nih.gov/28652578
Autor:
Jennifer R. Brown, Ma. Reina Improgo
Publikováno v:
Hematology/Oncology Clinics of North America. 27:157-171
This article discusses recent advances in genomic approaches used to understand chronic lymphocytic leukemia (CLL). We describe tools for analyzing DNA sequence level alterations, summarize data obtained from these various platforms, and discuss the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4628ad9592930e5a808db728c2e5b1
https://doi.org/10.1016/j.hoc.2013.01.001
https://doi.org/10.1016/j.hoc.2013.01.001
Autor:
Irene M. Ghobrial, Mick Correll, Jorge J. Castillo, Ma. Reina Improgo, Luisa Imberti, Jiantao Shi, Eliezer M. Van Allen, Jennifer R. Brown, Salomon Manier, Yawara Kawano, Adriana Perilla-Glen, Giuseppe Rossi, Yosra Aljawai, Antonio Sacco, Marco Chiarini, Michele Moschetta, Siobhan Glavey, Aldo M. Roccaro, Winston Hide, Matthew L. Freedman, Irene Rainville, Elaine Hiller, Steven P. Treon, Yuji Mishima
Publikováno v:
Blood. 127(21)
Familial aggregation of Waldenstrom macroglobulinemia (WM) cases, and the clustering of B-cell lymphoproliferative disorders among first-degree relatives of WM patients, has been reported. Nevertheless, the possible contribution of inherited suscepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df8ec34ea23e94c3cc4724584d427b05
https://pubmed.ncbi.nlm.nih.gov/26903547
https://pubmed.ncbi.nlm.nih.gov/26903547
Autor:
Ma. Reina Improgo, Laura E. MacConaill, Arnold S. Freedman, Nathalie Pochet, Stacey M. Fernandes, Megan Hanna, Aviv Regev, Jennifer R. Brown, Matthew L. Freedman, Bethany Tesar, Donna Neuberg, Lillian Werner
Publikováno v:
ResearcherID
Abstract 2875 Genome wide association studies (GWAS) in chronic lymphocytic leukemia (CLL) have identified thirteen single nucleotide polymorphisms (SNPs) that are associated with the risk of developing CLL but do not affect the coding regions of gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54360be7b292712ac2a823d7a82cd96
https://doi.org/10.1182/blood.v120.21.2875.2875
https://doi.org/10.1182/blood.v120.21.2875.2875
Autor:
Dan A. Landau, Gad Getz, Kristian Cibulskis, Adam Kiezun, Catherine J. Wu, Lillian Werner, Ma. Reina Improgo, Alexander R. Vartanov, Yaoyu E. Wang, Carrie Sougnez, Petar Stojanov, Bethany Tesar, Michael S. Lawrence, Stacey M. Fernandes, Jennifer R. Brown, Donna Neuberg
Publikováno v:
Blood. 120:560-560
Abstract 560 Nuclear factor kappa B (NF-κB) encompasses a family of transcription factors involved in oncogenic processes including cellular proliferation and apoptotic inhibition. Constitutive activation of NF-κB has been observed in hematologic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa7f7e31de2bc88e233a041594b1cc17
https://doi.org/10.1182/blood.v120.21.560.560
https://doi.org/10.1182/blood.v120.21.560.560