Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Małgorzata Z. Zdzienicka"'
Autor:
Natsuko Kondo, Akihisa Takahashi, Eiichiro Mori, Taichi Noda, Małgorzata Z. Zdzienicka, Larry H. Thompson, Thomas Helleday, Minoru Suzuki, Yuko Kinashi, Shinichiro Masunaga, Koji Ono, Masatoshi Hasegawa, Takeo Ohnishi
Publikováno v:
PLoS ONE, Vol 6, Iss 6 (2011)
Externí odkaz:
https://doaj.org/article/2c395d7258c147c5af00bb9791743477
Autor:
Alan Ashworth, Graeme C.M. Smith, Małgorzata Z. Zdzienicka, Andrew N. Tutt, Mark J. O'Connor, Sabrina Giavara, Sally Swift, Aneta Białkowska, Katarzyna Kluzek, Christopher J. Lord, Nicholas C. Turner, Nuala McCabe
Supplementary Tables S1 & S2 and Figures S1a & S1b from Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0275023ac8fe0956ac3319d08ea1d67d
https://doi.org/10.1158/0008-5472.22365228
https://doi.org/10.1158/0008-5472.22365228
Autor:
Alan Ashworth, Graeme C.M. Smith, Małgorzata Z. Zdzienicka, Andrew N. Tutt, Mark J. O'Connor, Sabrina Giavara, Sally Swift, Aneta Białkowska, Katarzyna Kluzek, Christopher J. Lord, Nicholas C. Turner, Nuala McCabe
Deficiency in either of the breast cancer susceptibility proteins BRCA1 or BRCA2 induces profound cellular sensitivity to the inhibition of poly(ADP-ribose) polymerase (PARP) activity. We hypothesized that the critical role of BRCA1 and BRCA2 in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6284321f9a1d48891dbcad412a2fde
https://doi.org/10.1158/0008-5472.c.6494592.v1
https://doi.org/10.1158/0008-5472.c.6494592.v1
Autor:
Katarzyna Kluzek, Małgorzata Z. Zdzienicka, Lidia Gackowska, Aleksandra M. Gorniewska, Izabela Kubiszewska, Aneta Białkowska
Publikováno v:
Molecular Medicine Reports
Repair of DNA interstrand crosslinks (ICLs) predominantly involves the Fanconi anemia (FA) pathway and homologous recombination (HR). The HR repair system eliminates DNA double strand breaks (DSBs) that emerge during ICLs removal. The current study p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fa7284f1ff6c6fb955274079f7752f
https://pubmed.ncbi.nlm.nih.gov/28627616
https://pubmed.ncbi.nlm.nih.gov/28627616
Autor:
Rebeka Sultana, Srinivasan Madhusudan, Charles A. Laughton, Małgorzata Z. Zdzienicka, Daniel R. McNeill, Haitham Qutob, Poulam M. Patel, Mohammed Z. Mohammed, David M. Wilson, Rachel Abbotts, Claire Seedhouse, Peter Fischer
Publikováno v:
International Journal of Cancer. 131:2433-2444
An apurinic/apyrimidinic (AP) site is an obligatory cytotoxic intermediate in DNA Base Excision Repair (BER) that is processed by human AP endonuclease 1 (APE1). APE1 is essential for BER and an emerging drug target in cancer. We have isolated novel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e763e7ef4c421ca6780a8327267bbd05
https://doi.org/10.1002/ijc.27512
https://doi.org/10.1002/ijc.27512
Autor:
Thomas Helleday, Natsuko Kondo, Ken Ohnishi, Małgorzata Z. Zdzienicka, Akihisa Takahashi, Larry H. Thompson, Noritomo Okamoto, Eiichiro Mori, Takeo Ohnishi, Yosuke Nakagawa, Taichi Noda, Hideo Asada
Publikováno v:
Biochemical and Biophysical Research Communications. 404:206-210
The role of the Fanconi anemia (FA) repair pathway for DNA damage induced by formaldehyde was examined in the work described here. The following cell types were used: mouse embryonic fibroblast cell lines FANCA(-/-), FANCC(-/-), FANCA(-/-)C(-/-), FAN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bddc615317e8f95da934b7d18f456df
https://doi.org/10.1016/j.bbrc.2010.11.094
https://doi.org/10.1016/j.bbrc.2010.11.094
Autor:
Małgorzata Z. Zdzienicka, Beata Wolska-Kusnierz, Dik C. van Gent, Rebecca E. E. Esveldt-van Lange, Matty Meyers, Bożena Mikołuć, Wouter W. Wiegant, Nicole S. Verkaik, Ron J. Romeijn, Firouz Darroudi, Hanna IJspeert, Anna A. Friedl, Ewa Bernatowska, Jean-Pierre de Villartay, Jacques J.M. van Dongen, Mirjam van der Burg, Leon H.F. Mullenders, Albert Pastink, Nicolaas G. J. Jaspers, Cees Vreeken
Publikováno v:
DNA Repair, 9(4), 365-373
DNA Repair, 9(4), 365-373. Elsevier
DNA Repair, 9(4), 365-373. Elsevier
V(D)J rearrangement in lymphoid cells involves repair of double-strand breaks (DSBs) through nonhomologous end joining (NHEJ). Defects in this process lead to increased radiosensitivity and severe combined immunodeficiency (RS-SCID). Here, a SCID pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::600d0be9fafaa126265f06f62a095b77
https://doi.org/10.1016/j.dnarep.2009.12.004
https://doi.org/10.1016/j.dnarep.2009.12.004
Autor:
Krystyna H. Chrzanowska, Johan P. de Winter, Małgorzata Z. Zdzienicka, Barbara C. Godthelp, Hans Joenje, Anneke B. Oostra, Markus Stumm, Petra van der Lelij, Martin A. Rooimans
Publikováno v:
van der Lelij, P, Chrzanowska, K H, Godthelp, B C, Rooimans, M A, Ostra, A B, Stumm, M, Zdzienicka, MZ, Joenje, H & de Winter, J P 2010, ' Warsaw Breakage Syndrome, a Cohesinopathy Associated with Mutations in the XPD Helicase Family Member DDX11/ChIR1 ', American journal of human genetics, vol. 86, no. 2, pp. 262-266 . https://doi.org/10.1016/j.ajhg.2010.01.008
American journal of human genetics, 86(2), 262-266. Cell Press
American Journal of Human Genetics, 86(2), 262-266
American journal of human genetics, 86(2), 262-266. Cell Press
American Journal of Human Genetics, 86(2), 262-266
The iron-sulfur-containing DNA helicases XPD, FANCJ, DDX11, and RTEL represent a small subclass of superfamily 2 helicases. XPD and FANCJ have been connected to the genetic instability syndromes xeroderma pigmentosum and Fanconi anemia. Here, we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71148f0773cd071c0f98138d44f9d6b3
Autor:
Nicola J. Curtin, Thomas Helleday, Ivaylo Stoimenov, Kate Sleeth, Evgenia Gubanova, Nicholas Pedley, Huw D. Thomas, T Djurenovic, Chatzakos, Małgorzata Z. Zdzienicka, Natalia Issaeva, Cecilia Lundin
Publikováno v:
Environmental and Molecular Mutagenesis. 50:515-590
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49498d15d0db13631497a3db311b7d08
https://doi.org/10.1002/em.20522
https://doi.org/10.1002/em.20522
Autor:
Małgorzata Z. Zdzienicka, Wynand P. Roos, Bernd Kaina, Steve Quiros, Olivia Kiedron, Teodora Nikolova, S C Naumann
Publikováno v:
DNA Repair. 8:72-86
O 6 -methylguanine (O 6 MeG) is a highly critical DNA adduct induced by methylating carcinogens and anticancer drugs such as temozolomide, streptozotocine, procarbazine and dacarbazine. Induction of cell death by O 6 MeG lesions requires mismatch rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa3f15bd2e18e67247371c2d77506a25
https://doi.org/10.1016/j.dnarep.2008.09.003
https://doi.org/10.1016/j.dnarep.2008.09.003