Výsledky vyhledávání - "Małgorzata Opydo-Chanek"

Akademický článek

In Vitro Effects of Vaspin on Porcine Granulosa Cell Proliferation, Cell Cycle Progression, and Apoptosis by Activation of GRP78 Receptor and Several Kinase Signaling Pathways Including MAP3/1, AKT, and STAT3

Autor: Patrycja Kurowska, Ewa Mlyczyńska, Monika Dawid, Małgorzata Opydo-Chanek, Joelle Dupont, Agnieszka Rak

Publikováno v: International Journal of Molecular Sciences, Vol 20, Iss 22, p 5816 (2019)

Vaspin, a visceral adipose tissue-derived serine protease inhibitor, is expressed in the porcine ovary; it induces the activation of various kinases and steroidogenesis. The aim of this study was to examine the effect of vaspin on granulosa (Gc) prol

Externí odkaz: https://doaj.org/article/89118df157b7418fb422b8e89d84f9e5

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The pan-Bcl-2 inhibitor obatoclax promotes differentiation and apoptosis of acute myeloid leukemia cells

Autor: Elzbieta Kolaczkowska, Lidia Mazur, Małgorzata Opydo-Chanek, Iwona Cichon, Agnieszka Rak

Publikováno v: Investigational New Drugs

SummaryOne of the key features of acute myeloid leukemia (AML) is the arrest of differentiation at the early progenitor stage of myelopoiesis. Therefore, the identification of new agents that could overcome this differentiation block and force leukem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010043d3370823940342a756e87a6292
https://doi.org/10.1007/s10637-020-00931-4

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Hematologia sportowa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11326c22fa3f499dc4a5022e1b3d1c2d
https://doi.org/10.53270/2021.026

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A mixture of persistent organic pollutants detected in human follicular fluid increases progesterone secretion and mitochondrial activity in human granulosa HGrC1 cells

Autor: Waclaw Tworzydlo, Weronika Marynowicz, Klaudia Jakubowska, Justyna Gogola-Mruk, Małgorzata Opydo-Chanek, Kinga Krawczyk, Anna Ptak

Publikováno v: Reproductive toxicology (Elmsford, N.Y.). 104

Disruption of granulosa cells (GCs), the main functional cells in the ovary, is associated with impaired female fertility. Epidemiological studies demonstrated that women have detectable levels of organic pollutants (e.g., perfluorooctanoate, perfluo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::934019cc7f5d0584bae97ce8d8900131
https://pubmed.ncbi.nlm.nih.gov/34311058

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Apelin and apelin receptor in human placenta: Expression, signalling pathway and regulation of trophoblast JEG‑3 and BeWo cells proliferation and cell cycle

Autor: Ewa Mlyczyńska, Eliza Drwal, Małgorzata Opydo-Chanek, Patrycja Kurowska, Waclaw Tworzydlo, Malgorzata Kotula-Balak, Agnieszka Rak

Publikováno v: International Journal of Molecular Medicine

Placentation requires the production of numerous growth factors, hormones and transcription factors. Many of them, like the adipose tissue-derived leptin or adiponectin, have been identified in the placenta and their role has been established in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6ba9df42815317d2c7ee58351d6cd4
https://doi.org/10.3892/ijmm.2020.4452

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Combination of ABT-737 and resveratrol enhances DNA damage and apoptosis in human T-cell acute lymphoblastic leukemia MOLT-4 cells

Autor: Agnieszka Cierniak, Lidia Mazur, Agnieszka Rak, Małgorzata Opydo-Chanek

Publikováno v: Toxicology in Vitro. 42:38-46

ABT-737 belongs to a new class of anticancer agents named BH3 mimetics. ABT-737 competitively binds to surface hydrophobic grooves of anti-apoptotic proteins of Bcl-2 family, counteracting their protective effect. Resveratrol is a natural polyphenol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d1bbee082dd7e8091888c4caf325dd
https://doi.org/10.1016/j.tiv.2017.03.013

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Chlorinated biphenyls effect on estrogen-related receptor expression, steroid secretion, mitochondria ultrastructure but not on mitochondrial membrane potential in Leydig cells

Autor: Malgorzata Kotula-Balak, Alicja Kamińska, Agnieszka Milon, Jerzy Galas, Waclaw Tworzydlo, Małgorzata Opydo-Chanek, Anna Ptak, Laura Pardyak

Publikováno v: Cell and Tissue Research

To characterize polychlorinated biphenyls (PCBs) action on Leydig cells, PCBs congeners, low-chlorinated (delor 103; d103) and high-chlorinated ones (delor 106; d106) were selected. The cells were treated according to PCBs dose (d103 or d106 0.2 ng/m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd5db50020794b4783dfad8a81cbf895
https://doi.org/10.1007/s00441-017-2596-x

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Autor: Ewa Mlyczyńska, Monika Dawid, Patrycja Kurowska, Agnieszka Rak, Joëlle Dupont, Małgorzata Opydo-Chanek

Publikováno v: International Journal of Molecular Sciences
Volume 20
Issue 22
International Journal of Molecular Sciences 22 (20), . (2019)
International Journal of Molecular Sciences, MDPI, 2019, 20 (22), ⟨10.3390/ijms20225816⟩
International Journal of Molecular Sciences, Vol 20, Iss 22, p 5816 (2019)

Vaspin, a visceral adipose tissue-derived serine protease inhibitor, is expressed in the porcine ovary
it induces the activation of various kinases and steroidogenesis. The aim of this study was to examine the effect of vaspin on granulosa (Gc)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::991004a9aacc5b0fb2d1cd9b7ef0e2a6

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Scrutinizing Mechanisms of the ‘Obesity Paradox in Sepsis’: Obesity Is Accompanied by Diminished Formation of Neutrophil Extracellular Traps (NETs) Due to Restricted Neutrophil–Platelet Interactions

Autor: Michal Santocki, Elzbieta Kolaczkowska, Weronika Ortmann, Małgorzata Opydo-Chanek, Iwona Cichon

Publikováno v: Cells
Volume 10
Issue 2
Cells, Vol 10, Iss 384, p 384 (2021)

Systemic inflammation is a detrimental condition associated with high mortality. However, obese individuals seem to have higher chances of surviving sepsis. To elucidate what immunological differences exist between obese and lean individuals we studi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e206f0d9b83997c35bdf7202530cca0b
https://doi.org/10.3390/cells10020384

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In Vitro Antileukemic Activity of Formamidine Epidoxorubicin Analogs

Autor: Irena Oszczapowicz, Urszula Kłaput, Barbara Janota, Katarzyna Śladowska, Lidia Mazur, Małgorzata Opydo-Chanek, Małgorzata Łukawska

Publikováno v: Anticancer Research. 37

Background/aim Epidoxorubicin is an anthracycline agent. The present study was undertaken to compare the antileukemic potential of epidoxorubicin and its two formamidine analogs containing either a morpholine moiety (EPIFmor) or a hexamethyleneimine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e007713eb1bcf2e799afcea5788a71
https://doi.org/10.21873/anticanres.12089

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