Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Małgorzata Brzoskwinia"'
Disruption of androgen signaling during puberty affects Notch pathway in rat seminiferous epithelium
Autor:
Alicja Kamińska, Sylwia Marek, Laura Pardyak, Małgorzata Brzoskwinia, Piotr Pawlicki, Barbara Bilińska, Anna Hejmej
Publikováno v:
Reproductive Biology and Endocrinology, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Onset of spermatogenesis at puberty is critically dependent on the activity of hypothalamic-pituitary-gonadal axis and testosterone production by Leydig cells. The aim of this study was to examine whether activation of Notch recep
Externí odkaz:
https://doaj.org/article/d7c3f399480946b1a229b7335bf8ae07
Autor:
Sylwia Lustofin, Alicja Kamińska, Małgorzata Brzoskwinia, Joanna Cyran, Małgorzata Kotula-Balak, Barbara Bilińska, Anna Hejmej
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 4, p 2284 (2022)
Delta/Serrate/LAG-2 (DSL) proteins, which serve as ligands for Notch receptors, mediate direct cell–cell interactions involved in the determination of cell fate and functioning. The present study aimed to explore the role of androgens and estrogens
Externí odkaz:
https://doaj.org/article/c2e1ddf3fcce47a9a74ea1a1c3bc04c7
Autor:
Alicja Kamińska, Sylwia Marek, Laura Pardyak, Małgorzata Brzoskwinia, Barbara Bilinska, Anna Hejmej
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8275 (2020)
Our recent study demonstrated altered expression of Notch ligands, receptors, and effector genes in testes of pubertal rats following reduced androgen production or signaling. Herein we aimed to explore the role of nuclear androgen receptor (AR) and
Externí odkaz:
https://doaj.org/article/b2a51536e7874289890945f870760ee8
Autor:
Sylwia Lustofin, Alicja Kamińska, Małgorzata Brzoskwinia, Joanna Cyran, Barbara Bilińska, Anna Hejmej
Publikováno v:
Endocrine Abstracts.
Publikováno v:
Endocrine Abstracts.
Autor:
Malgorzata Brzoskwinia, Laura Pardyak, Alicja Kaminska, Wacław Tworzydlo, Anna Hejmej, Sylwia Marek, Szczepan M. Bilinski, Barbara Bilinska
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Our present knowledge on interrelation between morphology/ultrastructure of mitochondria of the Leydig cell and its steroidogenic function is far from satisfactory and needs additional studies. Here, we analyzed the effects of blockade of an
Externí odkaz:
https://doaj.org/article/4a71d2da881b43479f8ab911f66dd912
Autor:
Malgorzata Brzoskwinia, Laura Pardyak, Agnieszka Rak, Alicja Kaminska, Anna Hejmej, Sylwia Marek, Malgorzata Kotula-Balak, Barbara Bilinska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 12, p 4439 (2020)
Adipokines influence energy metabolism and have effects on male reproduction, including spermatogenesis and/or Sertoli cell maturation; however, the relationship between these active proteins and androgens in testicular cells is limited. Here, we stu
Externí odkaz:
https://doaj.org/article/c840c6f63e66460c877db6668469fdde
Autor:
Michal Duliban, Ewelina Gorowska-Wojtowicz, Waclaw Tworzydlo, Agnieszka Rak, Malgorzata Brzoskwinia, Izabella Krakowska, Jan K. Wolski, Malgorzata Kotula-Balak, Bartosz J. Płachno, Barbara Bilinska
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3649 (2020)
Although epidemiological studies from the last years report an increase in the incidences of Leydig cell tumors (previously thought to be a rare disease), the biochemical characteristics of that tumor important for understanding its etiology, diagnos
Externí odkaz:
https://doaj.org/article/70879c8b5598441fb5e294038ee17f65