Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Małgorzata Anna Marć"'
Autor:
Karolina Witek, Aneta Kaczor, Ewa Żesławska, Sabina Podlewska, Małgorzata Anna Marć, Kinga Czarnota-Łydka, Wojciech Nitek, Gniewomir Latacz, Waldemar Tejchman, Markus Bischoff, Claus Jacob, Jadwiga Handzlik
Publikováno v:
Antibiotics, Vol 12, Iss 11, p 1618 (2023)
In this study, a search for new therapeutic agents that may improve the antibacterial activity of conventional antibiotics and help to successfully overcome methicillin-resistant Staphylococcus aureus (MRSA) infections has been conducted. The purpose
Externí odkaz:
https://doaj.org/article/b86e873063524db1aa3c92b6214f256f
Publikováno v:
Molecules, Vol 28, Iss 16, p 5959 (2023)
Bioorganic Chemistry is an emerging field developing at the interface between the traditional fields of Chemistry and Biochemistry [...]
Externí odkaz:
https://doaj.org/article/2d2b7cd8ab9d422a90e3fce90688f395
Autor:
Małgorzata Anna Marć, Enrique Domínguez-Álvarez, Gniewomir Latacz, Agata Doroz-Płonka, Carmen Sanmartín, Gabriella Spengler, Jadwiga Handzlik
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 367 (2022)
Prior studies have reported the potent and selective cytotoxic, pro-apoptotic, and chemopreventive activities of a cyclic selenoanhydride and of a series of selenoesters. Some of these selenium derivatives demonstrated multidrug resistance (MDR)-reve
Externí odkaz:
https://doaj.org/article/7f68274f37af44ffa692c3ed57c9f38e
Autor:
Veronica Vella, Marika Giuliano, Maria Luisa Nicolosi, Maria Giovanna Majorana, Małgorzata Anna Marć, Maria Grazia Muoio, Andrea Morrione, Marcello Maggiolini, Rosamaria Lappano, Ernestina Marianna De Francesco, Antonino Belfiore
Publikováno v:
Biomolecules, Vol 11, Iss 7, p 926 (2021)
The insulin receptor isoform A (IR-A), a dual receptor for insulin and IGF2, plays a role in breast cancer (BC) progression and metabolic reprogramming. Notably, discoidin domain receptor 1 (DDR1), a collagen receptor often dysregulated in cancer, is
Externí odkaz:
https://doaj.org/article/c31e0fc2af274ed4806b1f60f7dad858
Autor:
Małgorzata Anna Marć, Annamária Kincses, Bálint Rácz, Muhammad Jawad Nasim, Muhammad Sarfraz, Carlos Lázaro-Milla, Enrique Domínguez-Álvarez, Claus Jacob, Gabriella Spengler, Pedro Almendros
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 453 (2020)
Multidrug resistance of cancer cells to cytotoxic drugs still remains a major obstacle to the success of chemotherapy in cancer treatment. The development of new drug candidates which may serve as P-glycoprotein (P-gp) efflux pump inhibitors is a pro
Externí odkaz:
https://doaj.org/article/25bd7f125872415da98e670dd65a55fc
Autor:
Gergő Mótyán, Ádám Baji, Małgorzata Anna Marć, Mohana Krishna Gopisetty, Dóra I. Adamecz, Mónika Kiricsi, Éva A. Enyedy, Éva Frank
Publikováno v:
Applied Sciences, Vol 10, Iss 1, p 229 (2019)
Taking into account the pharmacological relevance of heterocycle-fused natural steroids, the objective of the current study was to develop a multistep reaction sequence for the efficient synthesis of novel D-ring-condensed 5-amino-1-arylpyrazoles fro
Externí odkaz:
https://doaj.org/article/fa472267a0364580a33e5b289a4d108a
Autor:
Tímea Mosolygó, Annamária Kincses, Andrea Csonka, Ádám Szabó Tönki, Karolina Witek, Carmen Sanmartín, Małgorzata Anna Marć, Jadwiga Handzlik, Katarzyna Kieć-Kononowicz, Enrique Domínguez-Álvarez, Gabriella Spengler
Publikováno v:
Molecules, Vol 24, Iss 8, p 1487 (2019)
Bacterial multidrug resistance is becoming a growing problem for public health, due to the development and spreading of bacterial strains resistant to antimicrobials. In this study, the antibacterial and multidrug resistance reversing activity of a s
Externí odkaz:
https://doaj.org/article/e074743c03164049a19744ee87fb7f36
Autor:
Gabriella Spengler, Márió Gajdács, Małgorzata Anna Marć, Enrique Domínguez-Álvarez, Carmen Sanmartín
Publikováno v:
Molecules, Vol 24, Iss 2, p 336 (2019)
Malignant diseases present a serious public health burden and their treatment with traditional chemotherapy cannot be considered an all-round solution, due to toxic side effects. Selenium compounds (Se-compounds) have received substantial attention i
Externí odkaz:
https://doaj.org/article/0a421a6cb3344188934f26b631759510
Autor:
Mónica Álvarez-Pérez, Wesam Ali, Małgorzata Anna Marć, Jadwiga Handzlik, Enrique Domínguez-Álvarez
Publikováno v:
Molecules, Vol 23, Iss 3, p 628 (2018)
Selenium and selenocompounds have attracted the attention and the efforts of scientists worldwide due to their promising potential applications in cancer prevention and/or treatment. Different organic selenocompounds, with diverse functional groups t
Externí odkaz:
https://doaj.org/article/cfe279f026544111a824dce3aaa767f4
Autor:
Karolina Witek, Muhammad Jawad Nasim, Markus Bischoff, Rosmarie Gaupp, Pavel Arsenyan, Jelena Vasiljeva, Małgorzata Anna Marć, Agnieszka Olejarz, Gniewomir Latacz, Katarzyna Kieć-Kononowicz, Jadwiga Handzlik, Claus Jacob
Publikováno v:
Molecules, Vol 22, Iss 12, p 2174 (2017)
In view of the pressing need to identify new antibacterial agents able to combat multidrug-resistant bacteria, we investigated a series of fused selenazolinium derivatives (1–8) regarding their in vitro antimicrobial activities against 25 ESKAPE-pa
Externí odkaz:
https://doaj.org/article/0b734f77933243c9919a1b19baf89157