Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Małgorzata, Kapral"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 10, Pp 11270-11281 (2024)
Galectin-3 (Gal-3) has been demonstrated to play a pivotal role in the pathogenesis of several fibrotic disorders. A number of studies have examined the relationship between galectin-3 levels and cardiac fibrosis in heart failure. Nevertheless, the r
Externí odkaz:
https://doaj.org/article/c5338e272a494c7fba0183c58fb7e870
Publikováno v:
Saudi Pharmaceutical Journal, Vol 31, Iss 7, Pp 1306-1316 (2023)
Melanoma is an aggressive skin cancer. Increasing evidence has shown the role of β-adrenergic receptors in the pathogenesis of melanoma. Carvedilol is a widely used non-selective β-AR antagonist with potential anticancer activity. The purpose of th
Externí odkaz:
https://doaj.org/article/17912b9bd8e84161b60210a4dba2cfcf
Publikováno v:
Medicina, Vol 59, Iss 12, p 2057 (2023)
Background and Objectives: Tachycardia is a common cardiovascular disease. Drugs blocking β1-adrenergic receptors (ADRB1) are used in the therapy of arrhythmogenic heart diseases. Disease-related polymorphisms can be observed within the ADRB1 gene.
Externí odkaz:
https://doaj.org/article/fcaf58ee24c341e680e322986ae12216
Publikováno v:
Molecules, Vol 27, Iss 2, p 369 (2022)
Pterostilbene is a dietary phytochemical that has been found to possess several biological activities, such as antioxidant and anti-inflammatory. Recent studies have shown that it exhibits the hallmark characteristics of an anticancer agent. The aim
Externí odkaz:
https://doaj.org/article/467a3c8d4e3c4d7c813a2a0cbeaa995d
Autor:
Aleksandra Morka, Lesław Szydłowski, Małgorzata Kapral, Ewa Moric-Janiszewska, Sławomir Smolik
Publikováno v:
Advances in Medical Sciences. 66:411-417
PURPOSE Aberrant expression of various miRNA species has been implicated in numerous cardiac diseases, e.g., heart failure, hypertrophy, conduction disturbances, and arrhythmogenesis. The aim of this study was to determine whether miR-1, miR-133a, an
Publikováno v:
Molecules, Vol 24, Iss 22, p 4153 (2019)
Inositol hexaphosphate (IP6), a natural dietary component, has been found as an antitumor agent by stimulating apoptosis and inhibiting cancer cell proliferation, their migration, and metastasis in diverse cancers including colon cancer. However, mol
Externí odkaz:
https://doaj.org/article/9f8d63ca70e1438693bd803796c7a8ae
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 2; Pages: 1115
Melanoma is one of the fastest-growing cancers worldwide. Treatment of advanced melanoma is very difficult; therefore, there is growing interest in the identification of new therapeutic agents. Pterostilbene is a natural stilbene that has been found
Autor:
Małgorzata Kapral, Joanna Wawszczyk, Katarzyna Jesse, Monika Paul-Samojedny, Dariusz Kuśmierz, Ludmiła Węglarz
Publikováno v:
Molecules, Vol 22, Iss 10, p 1657 (2017)
Abstract: AKT, a serine/threonine protein kinase and mammalian target of rapamycin (mTOR) plays a critical role in the proliferation and resistance to apoptosis that are essential to the development and progression of colon cancer. Therefore, AKT/mTO
Externí odkaz:
https://doaj.org/article/153869f06b814bc791a61e7a6c1fcd6a
Publikováno v:
Mediators of Inflammation, Vol 2013 (2013)
Transforming growth factor β (TGF-β) is a multifunctional cytokine recognized as an important regulator of inflammatory responses. The effect of inositol hexaphosphate (IP6), a naturally occurring phytochemical, on the mRNA expression of TGF-β1, T
Externí odkaz:
https://doaj.org/article/1dc5a6ca5cf74114802b70c8534ba98b
Publikováno v:
Acta Poloniae Pharmaceutica - Drug Research. 75:1161-1166