Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Małgorzata, Bondaryk"'
Autor:
Monika Staniszewska, Małgorzata Bondaryk, Magdalena Wieczorek, Eine Estrada-Mata, Hector Manuel Mora Montes, Zbigniew Ochal
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
We investigated the antifungal activity of novel a 2-bromo-2-chloro-2-(4-chlorophenylsulfonyl)-1-phenylethanone (compound 4). The synthesis of compound 4 was commenced from sodium 4-chlorobenzene sulfinate and the final product was obtained by treatm
Externí odkaz:
https://doaj.org/article/1a7110aeff19468cbb2bb57cdbecdffa
Autor:
Przemysław Biliński, Lucyna Kapka-Skrzypczak, Marek Posobkiewicz, Małgorzata Bondaryk, Piotr Hołownia, Andrzej Wojtyła
Publikováno v:
Annals of Agricultural and Environmental Medicine, Vol 19, Iss 856925, Pp 3-10 (2012)
Shiga toxin producing [i]Escherichia coli[/i] (STEC) are the most virulent diarrhoeagenic [i]E. coli [/i]known to date. They can spread with alarming ease via the food chain, as recently demonstrated by the large outbreak of STEC O104:H4 borne by spr
Externí odkaz:
https://doaj.org/article/034c31fb8f8d49c2b6dcf8c2db6256b6
Publikováno v:
Journal of Fungi, Vol 3, Iss 3, p 46 (2017)
Invasive fungal infections are associated with high mortality rates, despite appropriate antifungal therapy. Limited therapeutic options, resistance development and the high mortality of invasive fungal infections brought about more concern triggerin
Externí odkaz:
https://doaj.org/article/3839a878a61b44abaa14771190da0f82
Publikováno v:
Journal of Fungi, Vol 3, Iss 3, p 32 (2017)
We investigated the role of KEX2, SAP4-6, EFG1, and CPH1 in the virulence of Candida under a novel compound 2-bromo-2-chloro-2-(4-chlorophenylsulfonyl)-1-phenylethanone (Compound 4). We examined whether the exposure of C. albicans cells to Compound 4
Externí odkaz:
https://doaj.org/article/d163f5b8ebcb4f8aa4b38d1f6d723975
Autor:
Andrzej Wojtyła, Lucyna Kapka-Skrzypczak, Marek Posobkiewicz, Małgorzata Bondaryk, Piotr Hołownia, Henri-Jean Boulouis, Stanislawa Tylewska-Wierzbanowska
Publikováno v:
Annals of Agricultural and Environmental Medicine, Vol 19, Iss 856925, Pp 1-2 (2012)
For several decades, epidemics of chronic, non-contagious diseases have been observed in the developed countries worldwide. However, considerable health differences are noted between countries, even on the same continent, as well as between individua
Externí odkaz:
https://doaj.org/article/7126793d8d374a49a8f048125fa16841
Autor:
Małgorzata Bondaryk, Monika Staniszewska, Jolanta Mierzejewska, Małgorzata Milner-Krawczyk, Edyta Łukowska-Chojnacka
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:6058-6065
With the appearance of the antifungal resistance, novel antifungal agents need to be identified. In this context new 2,5-disubstituted tetrazole derivatives containing benzothiazole, benzoxazole or phenylsulfonyl moiety were synthesized by N-alkylati
Autor:
Jan K. Maurin, Monika Staniszewska, Maria Bretner, Małgorzata Bondaryk, Edyta Łukowska-Chojnacka
Publikováno v:
Chirality. 28:347-354
A series of new N-substituted benzimidazole derivatives was synthesized and their antifungal activity against Candida albicans was evaluated. The chemical step included synthesis of appropriate ketones containing benzimidazole ring, reduction of keto
Publikováno v:
Scopus-Elsevier
Warsaw University of Technology-OmegaPSIR
Warsaw University of Technology-OmegaPSIR
Secreted aspartic proteases (Saps) are considered as key virulence factors of Candida albicans. Hopefully our outlook will widen the knowledge of SAP7’s role in C. albicans pathogenesis. The goal of our study was to investigate SAP7 expression duri
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 34:1429-1435
The production of hydrolytic enzymes is considered a key virulence determinant of Candida albicans. Aminopeptidase 2 (Ape2) facilitates the penetration of C. albicans into the host tissue, by providing free amino acids to support fungal growth and pr
Publikováno v:
Archiv der Pharmazie. 348:132-143
The influence of halogenated methyl sulfones, i.e. bromodichloromethyl-4-chloro-3-nitrophenyl sulfone (named halogenated methyl sulfone 1), dichloromethyl-4-chloro-3-nitrophenyl sulfone (halogenated methyl sulfone 2), and chlorodibromomethyl-4-hydraz