Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maíra N. Pereira"'
Autor:
Maíra N. Pereira, Luma L. Nogueira, Marcilio Cunha-Filho, Tais Gratieri, Guilherme M. Gelfuso
Publikováno v:
Pharmaceutics, Vol 15, Iss 7, p 2002 (2023)
Nanotechnology has been investigated for treatments of hair follicle disorders mainly because of the natural accumulation of solid nanoparticles in the follicular openings following a topical application, which provides a drug “targeting effect”.
Externí odkaz:
https://doaj.org/article/bdb89bc30f434442b531d22415a88c46
Autor:
Breno N. Matos, Larissa M. A. Melo, Maíra N. Pereira, Thaiene A. Reis, Marcílio Cunha-Filho, Taís Gratieri, Guilherme M. Gelfuso
Publikováno v:
Química Nova, Vol 40, Iss 2, Pp 154-157
The experiments described in this paper tested the hypothesis whether iontophoresis applied on a chitosan nanoparticle formulation could combine the enhanced drug accumulation into the follicular casts obtained using iontophoresis and the sustained d
Externí odkaz:
https://doaj.org/article/35f59d219bbd426e8001c81e6031bdb0
Autor:
Antonio Alonso, Maíra N. Pereira, Felipe Q. Pires, Guilherme M. Gelfuso, Jorge L.V. Anjos, Tais Gratieri, Marcilio Cunha-Filho, Seila Tolentino
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 197
Hidradenitis suppurativa is a chronic and debilitating inflammatory condition related to a permanent obstruction of the pilosebaceous units. Until nowadays, therapeutic options are unsatisfactory. Here, we propose nanostructured lipid carriers (NLC)
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 159:331-340
Rifampicin (RIF) and clindamycin phosphate (CDM) are the main drugs currently used in combination to treat severe infectious diseases in hair follicles. This work describes a simple, rapid and sensitive method for simultaneous analysis of RIF and CDM
Autor:
Maíra N. Pereira, Tais Gratieri, Marcilio Ss Cunha-Filho, Camila Y. Ushirobira, Guilherme M. Gelfuso
Publikováno v:
Therapeutic Delivery. 9:593-603
Alopecia is the partial or total reduction of hair in a specific area of the skin that affects millions of men and women worldwide. Most common approved treatments present inconvenient therapeutic regimes and serious adverse effects. In this scenario
Autor:
Maíra N. Pereira, Tais Gratieri, Marcilio Cunha-Filho, Camila Y. Ushirobira, Luana A.F. Afiune, Guilherme M. Gelfuso
Publikováno v:
International journal of biological macromolecules. 151
In general, nanometer-sized drug delivery systems have a natural tendency for accommodation in the follicular cavities, which makes them advantageous in the treatment of conditions affecting these structures. Still, follicular targeting enhancement c
Autor:
Martha de Oliveira Bravo, Maíra N. Pereira, Tais Gratieri, Marcilio Cunha-Filho, Guilherme M. Gelfuso, Breno N. Matos, Felipe Saldanha-Araujo
Publikováno v:
International journal of biological macromolecules. 154
Tumors located in the oral mucosa are challenging to treat since surgery can lead to aesthetic, speech, and salivation problems, radiotherapy alone is often ineffective, and systemic chemotherapy brings meaningful side effects to the patient. Here, w
Publikováno v:
Carbohydrate Polymers. 253:117295
We developed chitosan or hyaluronic acid nanoparticles to entrap clindamycin and evaluated for the first time the impact of these two polymeric nanosystems on the targeted drug delivery to the pilosebaceous units, considering the sebaceous characteri
Autor:
Marcilio Cunha-Filho, Maíra N. Pereira, Mikaella C. de Sousa, Seila Tolentino, Guilherme M. Gelfuso, Tais Gratieri
Publikováno v:
Journal of Drug Delivery Science and Technology. 59:101895
Nanostructures have been proposed as drug delivery systems in the treatment of hair follicle-related conditions because of their well-reported tendency to accumulate into the hair follicle shafts extending drug release. However, little is known about
Autor:
Tais Gratieri, Marcilio Cunha-Filho, Maíra N. Pereira, Guilherme M. Gelfuso, Stephania G.B. Lima, Ludmila A.G. Pinho, Livia L. Sa-Barreto
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 161
A preformulation study with finasteride (FIN) was conducted to enable the development of a topical matrix system to treat androgenic alopecia. The compatibility of the drug with hidroxypropyl-β-cyclodextrin (HPβCD) and the hydrophilic polymers Kluc