Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Ma, Packham"'
Publikováno v:
Blood. 75(5)
Normal human platelets aggregated by thrombin undergo the release reaction and are not readily deaggregated by the combination of inhibitors hirudin, chymotrypsin, and prostaglandin E1 (PGE1). In contrast, thrombin-induced aggregates of platelets fro
Autor:
MA Packham, JF Mustard
Publikováno v:
Blood. 50:555-573
Publikováno v:
Blood. 71:850-860
The association of fibrinogen with washed human platelets was examined by immunocytochemistry during aggregation induced by adenosine diphosphate (ADP) and during deaggregation. The platelets were suspended either in a medium containing 2 mmol/L Ca2+
Publikováno v:
Blood. 71:1310-1320
Because thrombin aggregates afibrinogenemic platelets and platelets from patients with the gray platelet syndrome and because antibodies to fibrinogen inhibit thrombin-induced aggregation only at low concentrations of thrombin, the role of fibrinogen
Publikováno v:
Blood. 70:221-226
Platelets from two afibrinogenemic patients were used to determine whether fibrinogen is essential for platelet aggregation and to examine whether released fibrinogen contributes to the stabilization of platelet aggregates when platelets have been in
Publikováno v:
Blood. 70(3)
Close platelet-to-platelet contact induced by weak agonists in a medium with a low concentration of Ca2+ leads to thromboxane A2 (TXA2) formation, release of granule contents, and secondary aggregation. These responses do not occur in a medium contai
Publikováno v:
Blood. 53(5)
Autor:
ELISABETTA DEJANA, Jp, Cazenave, Mw, Hatton, Richardson M, Hm, Groves, Rl, Kinlough-Rathbone, Ma, Packham, Jf, Mustard
Publikováno v:
Europe PubMed Central
Rabbit aortae were removed from exsanguinated rabbits, washed, everted on probes, treated with thrombin, washed to remove unbound thrombin and used to measure the accumulation of 51Cr-labeled platelets in vitro. Thrombin pretreatment of normal rabbit
Publikováno v:
Blood. 66(2)
The controversy concerning the relationship between platelet buoyant density and platelet age is unresolved. Our earlier results with rabbit platelets indicate that the most-dense subpopulations are enriched in young platelets and that some platelets
Publikováno v:
Blood. 59(5)