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HDAC7 drives glioblastoma to a mesenchymal-like state via LGALS3-mediated crosstalk between cancer cells and macrophages.

Autor: Zhao S; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China.; Department of Neurosurgery, Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China., Zhao R; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Wang C; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Ma C; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Gao Z; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Li B; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Qi Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Qiu W; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Pan Z; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Wang S; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Guo Q; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Qiu J; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Fan Y; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Department of Neurosurgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong 250014, China., Guo X; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China.; Department of Neurology, Loma Linda University Health, Loma Linda 92350, California, USA., Xue H; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Deng L; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China., Li G; Department of Neurosurgery, Qilu Hospital, Cheeloo College of Medicine and Institute of Brain and Brain-Inspired Science, Shandong University, Jinan 250012, China.; Shandong Key Laboratory of Brain Health and Function Remodeling, Jinan 250012, China.

Publikováno v: Theranostics [Theranostics] 2024 Oct 21; Vol. 14 (18), pp. 7072-7087. Date of Electronic Publication: 2024 Oct 21 (Print Publication: 2024).