Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ma'ayan, Semo"'
Autor:
Kalyan Dulla, Monica Aguila, Amelia Lane, Katarina Jovanovic, David A. Parfitt, Iris Schulkens, Hee Lam Chan, Iris Schmidt, Wouter Beumer, Lars Vorthoren, Rob W.J. Collin, Alejandro Garanto, Lonneke Duijkers, Anna Brugulat-Panes, Ma’ayan Semo, Anthony A. Vugler, Patricia Biasutto, Peter Adamson, Michael E. Cheetham
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 12, Iss , Pp 730-740 (2018)
Leber congenital amaurosis type 10 (LCA10) is a severe inherited retinal dystrophy associated with mutations in CEP290. The deep intronic c.2991+1655A>G mutation in CEP290 is the most common mutation in LCA10 individuals and represents an ideal targe
Externí odkaz:
https://doaj.org/article/b75a727e464a462186e85d15a2057aba
Autor:
Selma, Tir, Laura C E, Steel, S K E, Tam, Ma'ayan, Semo, Carina A, Pothecary, Vladyslav V, Vyazovskiy, Russell G, Foster, Stuart N, Peirson
Publikováno v:
Progress in brain research. 273(1)
Over the last decades remarkable advances have been made in the understanding of the photobiology of circadian rhythms. The identification of a third photoreceptive system in the mammalian eye, in addition to the rods and cones that mediate vision, h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::84329c8e7253201dae664bf032e89061
https://pubmed.ncbi.nlm.nih.gov/35940726
https://pubmed.ncbi.nlm.nih.gov/35940726
Autor:
Timothy M Brown, Carlos Gias, Megumi Hatori, Sheena R Keding, Ma'ayan Semo, Peter J Coffey, John Gigg, Hugh D Piggins, Satchidananda Panda, Robert J Lucas
Publikováno v:
PLoS Biology, Vol 8, Iss 12, p e1000558 (2010)
Photoreception in the mammalian retina is not restricted to rods and cones but extends to a subset of retinal ganglion cells expressing the photopigment melanopsin (mRGCs). These mRGCs are known to drive such reflex light responses as circadian photo
Externí odkaz:
https://doaj.org/article/f698421633bd4aea9349226521715fe8
Autor:
Ma'ayan Semo, Carlos Gias, Ahmad Ahmado, Eriko Sugano, Annette E Allen, Jean M Lawrence, Hiroshi Tomita, Peter J Coffey, Anthony A Vugler
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15009 (2010)
Melanopsin photoreception plays a vital role in irradiance detection for non-image forming responses to light. However, little is known about the involvement of melanopsin in emotional processing of luminance. When confronted with a gradient in light
Externí odkaz:
https://doaj.org/article/2f8216fb16e1468083f92cde238100fd
Autor:
Amanda-Jayne Carr, Anthony A Vugler, Sherry T Hikita, Jean M Lawrence, Carlos Gias, Li Li Chen, David E Buchholz, Ahmad Ahmado, Ma'ayan Semo, Matthew J K Smart, Shazeen Hasan, Lyndon da Cruz, Lincoln V Johnson, Dennis O Clegg, Pete J Coffey
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8152 (2009)
Transformation of somatic cells with a set of embryonic transcription factors produces cells with the pluripotent properties of embryonic stem cells (ESCs). These induced pluripotent stem (iPS) cells have the potential to differentiate into any cell
Externí odkaz:
https://doaj.org/article/4af9d242b75a470aa5f97c662d3b9acc
Autor:
Patricia Biasutto, Anthony A. Vugler, Amelia Lane, Iris Schulkens, Michael E. Cheetham, David A. Parfitt, Mònica Aguilà, Rob W.J. Collin, Lonneke Duijkers, Peter Adamson, Wouter Beumer, Alejandro Garanto, Katarina Jovanovic, Iris Schmidt, Lars Vorthoren, Ma'ayan Semo, Anna Brugulat-Panes, Hee Lam Chan, Kalyan Dulla
Publikováno v:
Molecular Therapy-Nucleic Acids, 12, 730-740
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 730-740 (2018)
Molecular Therapy-Nucleic Acids, 12, pp. 730-740
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 12, Iss, Pp 730-740 (2018)
Molecular Therapy-Nucleic Acids, 12, pp. 730-740
Leber congenital amaurosis type 10 (LCA10) is a severe inherited retinal dystrophy associated with mutations in CEP290. The deep intronic c.2991+1655A>G mutation in CEP290 is the most common mutation in LCA10 individuals and represents an ideal targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b64a3b36f24df169882d7443d68110
http://hdl.handle.net/2066/195476
http://hdl.handle.net/2066/195476
Publikováno v:
Experimental Eye Research. 119:8-18
Maintenance of pupillary constriction in light-adapted rodents has traditionally been thought to involve a reflex between retina, brain and iris, with recent work identifying the melanopsin-expressing intrinsically photosensitive retinal ganglion cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4ff9c6b998986b02d21ec80c00e7f6
Publikováno v:
Investigative ophthalmologyvisual science. 57(1)
Following on from reports of retrograde retinal signaling in mice, we sought to investigate the influence of age and retinal location on this phenomenon using mice that lack rods and the majority of cones.We used functional anatomy for c-fos (Fos) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::271eeedc7840733090c2f35ad9dcf28f
https://pubmed.ncbi.nlm.nih.gov/26780315
https://pubmed.ncbi.nlm.nih.gov/26780315
Publikováno v:
Neurobiology of Aging. 33(2):383-392
Aging causes anatomical and functional changes in visual and circadian systems. In wild type mice rods, cones, and photosensitive retinal ganglion cells (pRGCs) decline with age. In rd/rd cl mice, the early loss of rods and cones is followed by protr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf06bff9555c076bfc95c562e0a19269
Publikováno v:
Expert Review of Ophthalmology. 6:585-588
Optogenetics is a technology using light to control the electrical activity of genetically targeted neurons in freely moving mammals [1]. Initial experiments used a blue-lightgated, cation-selective ion channel called channelrhodopsin2 (ChR2), taken
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ced7736fdd3b600804c92b6367f89b35
https://doi.org/10.1586/eop.11.68
https://doi.org/10.1586/eop.11.68