TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner

Autor: Xin Zeng, Lu Sun, Yan-Hua Du, Cheng-cui Huang, Ming-Ming Ma, Hua-Qing Zheng, Yong-Yuan Guan, Ya-juan Zhang, Xiaofei Lv, Xiao-long Li, Guan-Lei Wang

Publikováno v: Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3994-4007 (2021)
Acta Pharmaceutica Sinica. B

Vascular smooth muscle cell (VSMC) migration plays a critical role in the pathogenesis of many cardiovascular diseases. We recently showed that TMEM16A is involved in hypertension-induced cerebrovascular remodeling. However, it is unclear whether thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2252c02263eb5818f231c5b54829c2
http://www.sciencedirect.com/science/article/pii/S2211383521001416

Neuroendocrine and cardiac metabolic dysfunction and NLRP3 inflammasome activation in adipose tissue and pancreas following chronic spinal cord injury in the mouse

Autor: Valerie Bracchi-Ricard, Gregory E. Bigford, Mark S. Nash, John R. Bethea, Robert W. Keane

Publikováno v: ASN NEURO
ASN Neuro, Vol 5 (2013)

CVD (cardiovascular disease) represents a leading cause of mortality in chronic SCI (spinal cord injury). Several component risk factors are observed in SCI; however, the underlying mechanisms that contribute to these risks have not been defined. Cen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b63202e6d83a48dcfcd5252f49ab0c4
https://pubmed.ncbi.nlm.nih.gov/23924318

TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner.

Autor: Zheng H; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Li X; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Zeng X; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Huang C; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Ma M; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Lv X; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Zhang Y; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Sun L; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Wang G; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Du Y; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China., Guan Y; Department of Pharmacology, Cardiac & Cerebral Vascular Research Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.

Publikováno v: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2021 Dec; Vol. 11 (12), pp. 3994-4007. Date of Electronic Publication: 2021 Apr 22.