Zobrazeno 1 - 10
of 345
pro vyhledávání: '"MYPT1"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Introduction: Vasodilatation in response to NO is a fundamental response of the vasculature, and during aging, the vasculature is characterized by an increase in stiffness and decrease in sensitivity to NO mediated vasodilatation. Vascular tone is re
Externí odkaz:
https://doaj.org/article/15a795b98918469b9b56d5e82132cc86
Akademický článek
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Autor:
Declan Whyte, George Skalka, Peter Walsh, Ania Wilczynska, Nikki R. Paul, Claire Mitchell, Colin Nixon, William Clarke, Martin Bushell, Jennifer P. Morton, Daniel J. Murphy, Nathiya Muthalagu
Publikováno v:
Molecular Oncology, Vol 17, Iss 7, Pp 1212-1227 (2023)
The AMP‐activated protein kinase (AMPK)‐related kinase NUAK1 (NUAK family SNF1‐like kinase 1) has emerged as a potential vulnerability in MYC‐dependent cancer but the biological roles of NUAK1 in different settings are poorly characterised, a
Externí odkaz:
https://doaj.org/article/6896303684144ae5bf0d4de609aa31de
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 11, Iss 10, Pp n/a-n/a (2023)
Abstract Background Genitourinary and/or brain malformation syndrome (GUBS) is a recently discovered syndrome involving abnormalities of the neurological or urogenital system. PPP1R12A may be the pathological gene causing this syndrome. Currently, to
Externí odkaz:
https://doaj.org/article/a081ef7c15ce4aa0a2d1cf20876bbe5b
Autor:
Qingling Xie, Ren Liu, Zhihao Zou, Yuanfa Feng, Yiqiao Huang, Guibin Xu, Wei Sun, Yuxiang Liang, Weide Zhong
Publikováno v:
FEBS Open Bio, Vol 12, Iss 11, Pp 2083-2095 (2022)
Myosin phosphatase target subunit 1 (MYPT1) is a subunit of myosin phosphatase that is capable of regulating smooth muscle contraction. MYPT1 has been reported to be involved in a wide variety of tumours, but its expression and biological functions i
Externí odkaz:
https://doaj.org/article/88019a0142884fc3aa52971b52feaea6
Autor:
Zoltán Kónya, István Tamás, Bálint Bécsi, Beáta Lontay, Mária Raics, István Timári, Katalin E. Kövér, Ferenc Erdődi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4789 (2023)
Identification of specific protein phosphatase-1 (PP1) inhibitors is of special importance regarding the study of its cellular functions and may have therapeutic values in diseases coupled to signaling processes. In this study, we prove that a phosph
Externí odkaz:
https://doaj.org/article/390707bae2ac45368e599b4fb0844f02
Akademický článek
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Autor:
Sandra Muñoz-Galván, Blanca Felipe-Abrio, Eva M. Verdugo-Sivianes, Marco Perez, Manuel P. Jiménez-García, Elisa Suarez-Martinez, Purificacion Estevez-Garcia, Amancio Carnero
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Ovarian cancer is one of the most common and malignant cancers, partly due to its late diagnosis and high recurrence. Chemotherapy resistance has been linked to poor prognosis and is believed to be linked to the cancer stem cell (
Externí odkaz:
https://doaj.org/article/ad7f3ea6697f4f288783b7c2b9e5acc6
Publikováno v:
Neuropsychiatric Disease and Treatment, Vol Volume 15, Pp 3429-3442 (2019)
Wei-Ping Xiao,1,* Li-Li-Qiang Ding,2,* You-Jiang Min,1,3 Hua-Yuan Yang,4 Hai-Hua Yao,3 Jie Sun,1 Xuan Zhou,1 Xue-Bo Zeng,1 Wan Yu1 1Spinal Department of Orthopedics and Department of Acupuncture, Affiliated Hospital of Jiangxi University of Tradition
Externí odkaz:
https://doaj.org/article/1418c0310a1642499e78b7cbe538061a
Akademický článek
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