Zobrazeno 1 - 10
of 1 461
pro vyhledávání: '"MYOFIBROBLAST DIFFERENTIATION"'
Autor:
Tiewen Li, Yu Zhang, Zeng Zhou, Lvxin Guan, Yichen Zhang, Zhiyuan Zhou, Wenhao Wang, Xuehao Zhou, Di Cui, Chenyi Jiang, Yuan Ruan
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Myofibroblast buildup and prostatic fibrosis play a crucial role in the development of benign prostatic hyperplasia (BPH). Treatments specifically targeting myofibroblasts could be a promising approach for treating BPH. Tadalafil, a phosphod
Externí odkaz:
https://doaj.org/article/78faadf1dd8c4690b82d58f77a80fa82
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Background Extended contact with silica particles can lead to Silicosis, a chronic lung condition lacking established treatment protocols or clear mechanisms of development. The urgency for innovative treatments arises from the unavailabilit
Externí odkaz:
https://doaj.org/article/c9a10a8468204422a65d57041132ea02
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 178, Iss , Pp 117178- (2024)
Pulmonary fibrosis is a fatal and chronic lung disease that is characterized by accumulation of thickened scar in the lungs and impairment of gas exchange. The cases with unknown etiology are referred as idiopathic pulmonary fibrosis (IPF). There are
Externí odkaz:
https://doaj.org/article/f61dce4eaac947ffbebe7831f83994a3
Autor:
Qingzhong Hua, Lu Ren
Publikováno v:
Chinese Medicine, Vol 19, Iss 1, Pp 1-17 (2024)
Abstract Background At present, the treatment options available for idiopathic pulmonary fibrosis are both limited and often come with severe side effects, emphasizing the pressing requirement for innovative therapeutic alternatives. Myofibroblasts,
Externí odkaz:
https://doaj.org/article/570835e40ce444ee85d5ba2b785f59e1
Autor:
Patrick Hwang, Chung Min Shin, Jennifer A. Sherwood, DongHo Kim, Vineeth M. Vijayan, Krishna C. Josyula, Reid C. Millican, Donald Ho, Brigitta C. Brott, Vinoy Thomas, Chul Hee Choi, Sang-Ha Oh, Dong Woon Kim, Ho-Wook Jun
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-21 (2023)
Abstract Background Capsular contracture is a critical complication of silicone implantation caused by fibrotic tissue formation from excessive foreign body responses. Various approaches have been applied, but targeting the mechanisms of capsule form
Externí odkaz:
https://doaj.org/article/fbf83ed496fa4183868d6891e5c4aa1e
Autor:
Grace Choi, Eun-Young Lee, Dawoon Chung, Kichul Cho, Woon-Jong Yu, Sang-Jip Nam, Seong-Kook Park, Il-Whan Choi
Publikováno v:
Marine Drugs, Vol 22, Iss 1, p 39 (2024)
This study aims to explore the potential inhibition effects of staurosporine isolated from a Streptomyces sp. SNC087 strain obtained from seawater on nasal polyps. Staurosporine possesses antimicrobial and antihypertensive activities. This research f
Externí odkaz:
https://doaj.org/article/8c14ad7ab3304148b0f719c138305a5f
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17089 (2023)
Fibrosis and the associated decline in organ functionality lead to an almost 50% mortality rate in developed countries. Multipotent mesenchymal stromal cells (MSC) were shown to suppress the development and progression of fibrosis through secreted fa
Externí odkaz:
https://doaj.org/article/d6fa4cb010464da3b5e6d94e03dda696
Akademický článek
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Autor:
Aleksandra Malgorzata Siedlar, Tamara Seredenina, Anna Faivre, Yves Cambet, Marie-José Stasia, Dominik André-Lévigne, Marie-Luce Bochaton-Piallat, Brigitte Pittet-Cuénod, Sophie de Seigneux, Karl-Heinz Krause, Ali Modarressi, Vincent Jaquet
Publikováno v:
Redox Biology, Vol 60, Iss , Pp 102609- (2023)
Differentiation of fibroblasts to myofibroblasts is governed by the transforming growth factor beta (TGF-β) through a mechanism involving redox signaling and generation of reactive oxygen species (ROS). Myofibroblasts synthesize proteins of the extr
Externí odkaz:
https://doaj.org/article/507fecb164a84209b10ef09ff4779ba1
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
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