Zobrazeno 1 - 10
of 55
pro vyhledávání: '"MYCL1"'
Autor:
Ivo J Huijbers, Rahmen Bin Ali, Colin Pritchard, Miranda Cozijnsen, Min‐Chul Kwon, Natalie Proost, Ji‐Ying Song, Hilda de Vries, Jitendra Badhai, Kate Sutherland, Paul Krimpenfort, Ewa M Michalak, Jos Jonkers, Anton Berns
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 2, Pp 212-225 (2014)
Abstract Human cancers modeled in Genetically Engineered Mouse Models (GEMMs) can provide important mechanistic insights into the molecular basis of tumor development and enable testing of new intervention strategies. The inherent complexity of these
Externí odkaz:
https://doaj.org/article/eb23552beda443f999513453e1461b4a
Autor:
I. L. Plaksa, M. R. Savchuk, N. V. Shved, N. A. Savelov, D. N. Khmelkova, А. A. Isaev, R. V. Deev
Publikováno v:
Opuholi Golovy i Šei, Vol 11, Iss 1, Pp 78-85 (2021)
The study objective is to analyze the mutation profile of the tall cell variant (TCV) of papillary thyroid carcinoma (PTC).Materials and methods. The main inclusion criteria according to the WHO classification (2017) was PTC composed of at least 30 %
Publikováno v:
Pathology and Oncology Research
Purpose: The Myc family, especially C-MYC and MYCL1, has been found involved in small-cell lung carcinoma (SCLC). Identification of the frequency of C-MYC and MYCL1 expression among SCLC patients may help to identify potential targets for therapeutic
Autor:
Hamid Asadzadeh Aghdaei, Ahmad Majd, Amir Torshizi Esfahani, Ehsan Nazemalhosseini Mojarad, Seyed Yoosef Seyedna
Publikováno v:
Journal of Cellular Physiology. 234:13128-13136
Background Microsatellite instability (MSI) is a prognostic marker in colorectal cancer (CRC). The biological significance of MSI-low (MSI-L) phenotype and its differences with microsatellite stable (MSS) phenotype remains unclear. The aim of this st
Autor:
V Ravi, R Madison, AB Schrock, G Cote, S Millis, R Alvarez, E Choy, D Katz, J Chung, L Gay, VA Miller, JS Ross, SM Ali, S Schnitt
Publikováno v:
Cancer Research. 77:P2-12
Background: Angiosarcoma of the breast (BAS) is a rare but lethal neoplasia, either arising de novo or secondary to radiation therapy, with incidence of the latter disease increasing. We queried a database of more than 70,000 advanced cancer patients
Autor:
W.H. Kim, H.E. Chang, S.Y. Lee, Heung Kwon Oh, K.U. Park, A.N. Seo, S.-B. Kang, Hye Seung Lee, S.K. Nam, M.H. lhn, D.-W. Kim
Publikováno v:
Current Molecular Medicine. 16:829-839
Purpose: Recently, a different type of microsatellite instability (MSI) instability designated ‘elevated microsatellite alterations at selected tetranucleotide repeats’ (EMAST) has been reported in several neoplasms, but its clinical implications
Publikováno v:
Cell biochemistry and function. 37(4)
MYCL1 protein expression encoded by a proto-oncogene MYCL1, a member of the MYC family, is correlated with poor prognosis in gastric cancer patients. Nevertheless, the role of MYCL1 in gastric cancer cells remains unknown. In this study, the expressi
Akademický článek
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Autor:
Triantafyllia R. Karakousi, Alvaro Quintanal Villalonga, Andrea Ventura, Triparna Sen, Thales Papagiannakopoulos, Charles M. Rudin, John T. Poirier, Metamia Ciampricotti, Viola Allaj
Publikováno v:
Cancer Research. 80:420-420
Background: Small cell lung cancer (SCLC) is the most aggressive subtype of lung cancer, accounting for about 15% of all lung cancer cases and approximately 200,000 deaths per year. SCLC genetic alterations are characterized by near-universal loss of
Publikováno v:
Biochemical and Biophysical Research Communications. 456:879-883
As a member of the Myc proto-oncogene family, MYCL1 has been found to be amplified and overexpressed in some malignancies. However, the clinical significance of Mycl1 expression in gastric cancer is still unknown. Mycl1 expression was detected on tis