Phase I/II study of intermittent all-trans-retinoic acid, alone and in combination with interferon alfa-2a, in patients with epidemic Kaposi's sarcoma

Autor: Robert Yarchoan, S Bauza, Robert F. Murphy, Andrea Foli, Roger B. Cohen, Samuel Broder, James M. Pluda, J Bailey, MW Saville, Peter C. Adamson

Publikováno v: Journal of Clinical Oncology. 13:1966-1974

PURPOSE A phase I/II study of oral all-trans-retinoic acid (ATRA; tretinoin), administered every other week alone and then in combination with interferon (IFN) alfa-2a, was undertaken to evaluate the activity, toxicity, and pharmacokinetics of this r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::192fee40733d9816e4a5ca79cf98b029
https://doi.org/10.1200/jco.1995.13.8.1966

Phase II trial with dose titration of paclitaxel for the therapy of human immunodeficiency virus-associated Kaposi's sarcoma

Autor: William D. Figg, MW Saville, D Tuck, Wyndham H. Wilson, Robert Yarchoan, Ellen Feigal, Jeanne Odom, Samuel Broder, Jill Lietzau, Seth M. Steinberg, M T Fajardo, R. W. Humphrey, James M. Pluda, Richard Lush, I. Feuerstein, Kathleen M. Wyvill, Lauri Welles

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 16(3)

PURPOSE To investigate the antitumor activity and safety of paclitaxel in patients with advanced human immunodeficiency virus (HIV)-associated Kaposi's sarcoma (KS). PATIENTS AND METHODS Twenty-nine patients with advanced HIV-associated KS were enrol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f636f64bb6b544a3207353cf26e80d
https://pubmed.ncbi.nlm.nih.gov/9508198

Kaposi's sarcoma (KS)-associated herpesvirus-like DNA sequences in peripheral blood mononuclear cells: association with KS and persistence in patients receiving anti-herpesvirus drugs

Autor: RW Humphrey, TR O'Brien, FM Newcomb, H Nishihara, KM Wyvill, GA Ramos, MW Saville, JJ Goedert, SE Straus, R Yarchoan

Publikováno v: Blood. 88(1)

Herpesvirus-like DNA sequences (KSHV/HHV-8) have recently been described in AIDS-associated Kaposi's sarcoma (KS) lesions. Many questions remain regarding the role of this virus in KS and the therapeutic implications of this finding. In the current s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49c10689dbada0dc131558aa383eb0db
https://pubmed.ncbi.nlm.nih.gov/8704186

Phase I-II study of OBI-888, a humanized monoclonal IgG1 antibody against the tumor-associated carbohydrate antigen Globo H, in patients with advanced solid tumors.

Autor: Tsimberidou AM; Department of Investigational Cancer Therapeutics, Katherine Russell Dixie Distinguished Endowed Professor, The University of Texas MD Anderson Cancer Center, Unit 455, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. atsimber@mdanderson.org., Grothey A; Gastrointestinal Cancer Research at West Cancer Center and Research Institute, Germantown, TN, USA., Sigal D; Scripps Clinic and Scripps Cancer Center, La Jolla, CA, USA., Lenz HJ; Keck School of Medicine, USC Norris Comprehensive Cancer Center, Los Angeles, CA, USA., Hochster HS; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA., Chao Y; Taipei Veterans General Hospital, Taipei, Taiwan., Bai LY; China Medical University Hospital, Taichung City, Taiwan., Yen CL; National Cheng Kung University Hospital, Tainan, Taiwan., Xu D; OBI Pharma USA, Inc, San Diego, CA, USA., Saville MW; OBI Pharma USA, Inc, San Diego, CA, USA.

Publikováno v: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2024 Dec; Vol. 94 (6), pp. 787-798. Date of Electronic Publication: 2024 Sep 23.

Rituximab plus fludarabine and cyclophosphamide prolongs progression-free survival compared with fludarabine and cyclophosphamide alone in previously treated chronic lymphocytic leukemia.

Autor: Robak T; Department of Hematology, Medical University of Lodz, Ciolkowskiego 2, Lodz, Poland 93-510. robaktad@csk.umed.lodz.pl, Dmoszynska A, Solal-Céligny P, Warzocha K, Loscertales J, Catalano J, Afanasiev BV, Larratt L, Geisler CH, Montillo M, Zyuzgin I, Ganly PS, Dartigeas C, Rosta A, Maurer J, Mendila M, Saville MW, Valente N, Wenger MK, Moiseev SI

Publikováno v: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2010 Apr 01; Vol. 28 (10), pp. 1756-65. Date of Electronic Publication: 2010 Mar 01.