Zobrazeno 1 - 10
of 22
pro vyhledávání: '"MVB, multivesicular body"'
Autor:
Yihui Yang, Xiangjin Zheng, Sha Li, Jinyi Liu, Wan Li, Jie Yi, Weiqi Fu, Jinhua Wang, Guanhua Du, Liwen Ren
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2783-2797 (2021)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon fusion of multivesicular bodies with the cell surface. They can transport nucleic acids, proteins, and lipids for intercellular communication and activate signalin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfeee0d62636797c4da5264a84ca925
https://doi.org/10.1016/j.apsb.2021.01.001
https://doi.org/10.1016/j.apsb.2021.01.001
Autor:
Evelyn Seelow, Eberhard Hildt, Denna Tabari, Kathrin Woytinek, David Heiler Martín, Catharina Scholl, Julia C. Stingl, Mira Choi, Benjamin Schmidt, Mirco Glitscher
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 159-180 (2021)
Cellular and Molecular Gastroenterology and Hepatology : CMGH 12, 159-180 (2021). doi:10.1016/j.jcmgh.2021.02.002
Cellular and Molecular Gastroenterology and Hepatology, 12(1):159-180
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology : CMGH 12, 159-180 (2021). doi:10.1016/j.jcmgh.2021.02.002
Cellular and Molecular Gastroenterology and Hepatology, 12(1):159-180
Cellular and Molecular Gastroenterology and Hepatology
Background and aims The Hepatitis E virus hijacks the endosomal system for its release. These structures are highly dependent on cholesterol. Hence, this study investigates the impact of HEV on cholesterol-metabolism, the effect of intracellular chol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f49a05084d5deba44d573f372cd16e
http://www.sciencedirect.com/science/article/pii/S2352345X21000357
http://www.sciencedirect.com/science/article/pii/S2352345X21000357
Publikováno v:
Translational Oncology, Vol 14, Iss 12, Pp 101231-(2021)
Translational Oncology
Translational Oncology
Highlights • EVs mediate the interaction between tumor and stromal cells in the TME. • Tumors mediate CAF-like activation of stromal cells through EVs. • CAF-derived EVs promote tumor proliferation, metastasis and therapeutic resistance.
C
C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc5dbb220f9849b850d3378d75eced1b
http://www.sciencedirect.com/science/article/pii/S1936523321002230
http://www.sciencedirect.com/science/article/pii/S1936523321002230
Publikováno v:
Progress in Lipid Research
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic that has infected over a hundred million people globally. There have been more than two million deaths recorded worldwide, with no end in sight until a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5395ff711ceb9515b0a578943612b9c
Autor:
Alberto Carpinteiro Soares, Jonas Mariën, Edward B. Lee, John Q. Trojanowski, Charlotte Delay, Andreia Ferreira, Dieder Moechars, Louis De Muynck, Wim Annaert
Publikováno v:
The Journal of Biological Chemistry
Tauopathies, such as Alzheimer's disease (AD), are neurodegenerative disorders characterized by the deposition of hyperphosphorylated tau aggregates. Proteopathic tau seeds spread through the brain in a temporospatial pattern, indicative of transsyna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::059fec311317b31ce0a89c1ba747e1e8
https://pubmed.ncbi.nlm.nih.gov/33831417
https://pubmed.ncbi.nlm.nih.gov/33831417
Autor:
Chise Tateno, Naoki Yamamoto, Chihiro Yamasaki, Takahiro Ochiya, Yuichi Hirata, Michinori Kohara, Yutaka Naito, Yoshiaki Kikkawa, Yuji Ishida, Takahiro Sanada
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 2, Pp 272-283 (2017)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims: An extracellular vesicle (EV) is a nanovesicle that shuttles proteins, nucleic acids, and lipids, thereby influencing cell behavior. A recent crop of reports have shown that EVs are involved in infectious biology, influencing host
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20811b2d6ba724680e397501298aad87
https://doi.org/10.1016/j.jcmgh.2016.10.003
https://doi.org/10.1016/j.jcmgh.2016.10.003
Publikováno v:
Neurobiology of Disease, Vol 98, Iss, Pp 77-87 (2017)
Neurobiology of Disease
Neurobiology of Disease
Saposin deficiency is a childhood neurodegenerative lysosomal storage disorder (LSD) that can cause premature death within three months of life. Saposins are activator proteins that promote the function of lysosomal hydrolases that mediate the degrad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11889ee001ce34295528f3cb25dcc361
https://doi.org/10.1016/j.nbd.2016.11.012
https://doi.org/10.1016/j.nbd.2016.11.012
Publikováno v:
The Journal of Biological Chemistry
The voltage-gated potassium channel Kv1.5 plays important roles in the repolarization of atrial action potentials and regulation of the vascular tone. While the modulation of Kv1.5 function has been well studied, less is known about how the protein l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079b86ed220531bc212b208ac2fe6d86
https://doi.org/10.1016/j.jbc.2021.100514
https://doi.org/10.1016/j.jbc.2021.100514
Publikováno v:
EBioMedicine
EBioMedicine, Vol 38, Iss, Pp 273-282 (2018)
EBioMedicine, Vol 38, Iss, Pp 273-282 (2018)
Neural stem cell (NSC) grafting in conditions such as aging, brain injury, and neurodegenerative diseases promotes regeneration, plasticity and functional recovery. Recent studies have revealed that administration of NSC-derived extracellular vesicle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911fdd39844daf582397cad484df1e9f
https://pubmed.ncbi.nlm.nih.gov/30472088
https://pubmed.ncbi.nlm.nih.gov/30472088
Autor:
Alexandre A. Mironov, Tor Erik Rusten, Galina V. Beznoussenko, Thomas Vaccari, Harald Stenmark, David Bilder, Valeria Mastrodonato, Pierpaolo Ginefra, Elena Morelli
Publikováno v:
Autophagy
Autophagy, vol 10, iss 12
Autophagy, vol 10, iss 12
How autophagic degradation is linked to endosomal trafficking routes is little known. Here we screened a collection of uncharacterized Drosophila mutants affecting membrane transport to identify new genes that also have a role in autophagy. We isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcde934b1ebd3794834512bd341d4be7
http://europepmc.org/articles/PMC4502674
http://europepmc.org/articles/PMC4502674