An overview of SARS-COV-2 epidemiology, mutant variants, vaccines, and management strategies

Autor: Almas Hanif Mulla, Jonaid Ahmad Malik, Turki Al Hagbani, Saleh Alghamdi, Sirajudheen Anwar, Mohammed Abrar Ubaid, Khaled Almansour, Tahmeena Farooqi

Publikováno v: Journal of Infection and Public Health
Journal of Infection and Public Health, Vol 14, Iss 10, Pp 1299-1312 (2021)

Background: Over the last two decades, humanity has observed the extraordinary anomaly caused by novel, weird coronavirus strains, such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). As the severe acute respi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e52f40144e1e7ce6b0a01b1925ad493
https://doi.org/10.1016/j.jiph.2021.08.014

Elements in the Development of a Production Process for Modified Vaccinia Virus Ankara

Autor: Volker Sandig, Udo Reichl, Verena Lohr, Yvonne Genzel, Ingo Jordan

Publikováno v: Microorganisms, Vol 1, Iss 1, Pp 100-121 (2013)

The production of several viral vaccines depends on chicken embryo fibroblasts or embryonated chicken eggs. To replace this logistically demanding substrate, we created continuous anatine suspension cell lines (CR and CR.pIX), developed chemically-de

Externí odkaz: https://doaj.org/article/825292b1b41540fa85509e2b13dfbcb7

UK vaccines network: Mapping priority pathogens of epidemic potential and vaccine pipeline developments

Autor: Andrew J. H. Simpson, Mark P. Stevens, Gary Entrican, Christopher J. M. Whitty, Roger Hewson, Anthony R. Fooks, Joann L. Prior, Karl Simpson, Anna M. Kinsey, Margaret J Hosie, Rob Noad, Sarah C. Gilbert, Miles W. Carroll

Publikováno v: VACCINE
Vaccine
Noad, R J, Simpson, K, Fooks, A R, Hewson, R, Gilbert, S C, Stevens, M P, Hosie, M J, Prior, J, Kinsey, A M, Entrican, G, Simpson, A, Whitty, C J M & Carroll, M W 2019, ' UK vaccines network : Mapping priority pathogens of epidemic potential and vaccine pipeline developments ', Vaccine . https://doi.org/10.1016/j.vaccine.2019.09.009

During the 2013-2016 Ebola outbreak in West Africa an expert panel was established on the instructions of the UK Prime Minister to identify priority pathogens for outbreak diseases that had the potential to cause future epidemics. A total of 13 prior

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01e52dc2838d9b8d90c847268c38af5
https://ora.ox.ac.uk/objects/uuid:a1f9504d-92ad-4e1c-9b83-1fe191f50a4b

Targets and strategies for vaccine development against SARS-CoV-2

Autor: Tahmeena Farooqi, Kannan R.R. Rengasamy, Sirajudheen Anwar, Faheem Hyder Pottoo, Jonaid Ahmad Malik, Almas Hanif Mulla

Publikováno v: Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy, Vol 137, Iss, Pp 111254-(2021)

Graphical abstract
Highlights • The potential antigen targets are being utilized for the formulation of an effective vaccine. Spike protein is the most utilized antigen target for vaccine development, however other structural and non-structura

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ab65f9901da2f7c2301716f0c92c14
https://doi.org/10.1016/j.biopha.2021.111254

An infected chicken kidney cell co-culture ELISpot for enhanced detection of T cell responses to avian influenza and vaccination

Autor: Marylene Y. Peroval, Karen Staines, Devanand Balkissoon, C. Butter, Adrian Smith, Raul Ruiz-Hernandez, Amy Boyd

Publikováno v: Journal of Immunological Methods

A better understanding of the immune responses of chickens to the influenza virus is essential for the development of new strategies of vaccination and control. We have developed a method incorporating infected chicken kidney cells (CKC) in culture w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f65e97172036768fccaeaeed9a8b10
https://pubmed.ncbi.nlm.nih.gov/25450002