Hepatocellular carcinomas, exhibiting intratumor fibrosis, express cancer-specific extracellular matrix remodeling and WNT/TGFB signatures, associated with poor outcome.

Autor: Desert R; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA., Chen W; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA., Ge X; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA., Viel R; Univ Rennes, CNRS, INSERM, UMS Biosit, Rennes, France., Han H; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA., Athavale D; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA., Das S; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA., Song Z; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA., Lantvit D; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA., Cano L; INSERM, Univ Rennes, Nutrition, Métabolismes et Cancer (NuMeCan), 2 Rue Henri le Guilloux, Rennes, France., Naba A; Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, Illinois, USA.; University of Illinois Cancer Center, Chicago, Illinois, USA., Musso O; INSERM, Univ Rennes, Nutrition, Métabolismes et Cancer (NuMeCan), 2 Rue Henri le Guilloux, Rennes, France., Nieto N; Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, USA.; University of Illinois Cancer Center, Chicago, Illinois, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2023 Sep 01; Vol. 78 (3), pp. 741-757. Date of Electronic Publication: 2023 Apr 01.

SARS-CoV-2 receptor ACE2 is upregulated by fatty acids in human MASH.

Autor: Cano L; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France., Desquilles L; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France., Ghukasyan G; Univ Rennes 1, CNRS, INSERM, UMS Biosit, Core Facility H2P2, Rennes, France., Angenard G; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France., Landreau C; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France., Corlu A; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France., Clément B; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France., Turlin B; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France., Le Ferrec E; Univ Rennes 1, INSERM, EHESP, IRSET (Institut de Recherche en Santé Environnement et Travail) UMR_S 1085, Rennes, France., Aninat C; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France., Massart J; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France., Musso O; INSERM, INRAE, Univ Rennes 1, Nutrition Metabolisms and Cancer, Rennes, France.

Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2023 Oct 13; Vol. 6 (1), pp. 100936. Date of Electronic Publication: 2023 Oct 13 (Print Publication: 2024).

Modeling liver hereditary hemorrhagic telangiectasia with right heart overload to the core of liver sinusoidal endothelial cells.

Autor: Musso O; INSERM, INRAE , Univ Rennes , Nutrition Metabolism and Cancer , Rennes , France.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2023 Apr 01; Vol. 77 (4), pp. 1081-1084. Date of Electronic Publication: 2022 Sep 12.

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Role of Hepatocyte-Derived Osteopontin in Liver Carcinogenesis.

Autor: Desert R; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Ge X; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA.; Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Song Z; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Han H; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Lantvit D; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Chen W; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Das S; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Athavale D; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Abraham-Enachescu I; Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Blajszczak C; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Chen Y; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Musso O; INSERM, University of Rennes, INRA, Institut NuMeCAN (Nutrition Metabolisms and Cancer), Rennes, France., Guzman G; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA., Hoshida Y; Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Liver Tumor Translational Research Program, Harold C. Simmons Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA., Nieto N; Department of Pathology, University of Illinois at Chicago, Chicago, IL, USA.; Division of Liver Diseases, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Division of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA.

Publikováno v: Hepatology communications [Hepatol Commun] 2022 Apr; Vol. 6 (4), pp. 692-709. Date of Electronic Publication: 2021 Nov 03.