Zobrazeno 1 - 10
of 39
pro vyhledávání: '"MTfp"'
Autor:
Xiu Jin, Jing Su, Qinyu Zhao, Ruiting Li, Jianlu Xiao, Xiaomei Zhong, Li Song, Yi Liu, Kaiqin She, Hongxin Deng, Yuquan Wei, Yang Yang
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 25, Iss , Pp 370-381 (2022)
Mucopolysaccharidosis type I-Hurler (MPS I-H) is a neurodegenerative lysosomal storage disorder (LSD) caused by inherited defects of the α-L-iduronidase (IDUA) gene. Current treatments are ineffective for treating central nervous system (CNS) manife
Externí odkaz:
https://doaj.org/article/b79b3ec1851841d8bf8f9ad802dc0a45
Autor:
Chaahat S. B. Singh, Brett A. Eyford, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Mark Okon, Timothy Z. Vitalis, Reinhard Gabathuler, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of diseases of the brain. Our previous studies demonstrated that that a soluble form of melanotransferrin (MTf; Uniprot P08582; also known as p97, MFI2, and
Externí odkaz:
https://doaj.org/article/288f8666a28c48d19137c9e3c081e799
Autor:
Brett A. Eyford, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Reinhard Gabathuler, Jacob A. Gordon, Hans Adomat, Emma S.T. Guns, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/7daf6dbc7b4446ec819ea423dd4285c0
Autor:
Brett A. Eyford, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Reinhard Gabathuler, Jacob A. Gordon, Hans Adomat, Emma S.T. Guns, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of neuroinflammation (NI) of the central nervous system. A twelve-amino acid peptide that transcytoses the BBB, termed MTfp, was chemically conjugated to si
Externí odkaz:
https://doaj.org/article/a03a0a8be37540beb76b28f2d46208c8
Publikováno v:
Global Health Research and Policy, Vol 3, Iss 1, Pp 1-13 (2018)
Abstract Background The pursuit of efficiency and productivity is one of the goals of health systems. In the era of Sustainable Development Goals and particularly the move towards universal health coverage, it is imperative to curb wastage of resourc
Externí odkaz:
https://doaj.org/article/1ee964e96a3c4abd8482c0aacefef2ea
Akademický článek
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Akademický článek
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Autor:
Brett A. Eyford, Chaahat S. B. Singh, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Tracy Hill, Rhonda Hildebrandt, Ian Welch, Timothy Z. Vitalis, Reinhard Gabathuler, Jacob A. Gordon, Hans Adomat, Emma S.T. Guns, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences, Vol 8 (2021)
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of neuroinflammation (NI) of the central nervous system. A twelve-amino acid peptide that transcytoses the BBB, termed MTfp, was chemically conjugated to si
Autor:
Chaahat S. B. Singh, Brett A. Eyford, Thomas Abraham, Lonna Munro, Kyung Bok Choi, Mark Okon, Timothy Z. Vitalis, Reinhard Gabathuler, Chieh-Ju Lu, Cheryl G. Pfeifer, Mei Mei Tian, Wilfred A. Jefferies
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience, Vol 15 (2021)
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of diseases of the brain. Our previous studies demonstrated that that a soluble form of melanotransferrin (MTf; Uniprot P08582; also known as p97, MFI2, and
Publikováno v:
Global Health Research and Policy, Vol 3, Iss 1, Pp 1-13 (2018)
Global Health Research and Policy
Global Health Research and Policy
Background The pursuit of efficiency and productivity is one of the goals of health systems. In the era of Sustainable Development Goals and particularly the move towards universal health coverage, it is imperative to curb wastage of resources to ens