Zobrazeno 1 - 10
of 524
pro vyhledávání: '"MTS, mitochondrial targeting sequence"'
Autor:
Milana Fraiberg, Boris Macek, Zvulun Elazar, Philipp J. Kahle, Anna Lechado Terradas, Katharina Zittlau
Publikováno v:
The Journal of Biological Chemistry
The journal of biological chemistry 297(5), 101339 (2021). doi:10.1016/j.jbc.2021.101339
The journal of biological chemistry 297(5), 101339 (2021). doi:10.1016/j.jbc.2021.101339
Mitochondria are important organelles in eukaryotes. Turnover and quality control of mitochondria are regulated at the transcriptional and posttranslational level by several cellular mechanisms. Removal of defective mitochondrial proteins is mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbec8d603702bfc18179f4f97b4c81b
http://europepmc.org/articles/PMC8591368
http://europepmc.org/articles/PMC8591368
Autor:
Zhang, Yu1 (AUTHOR), Karmon, Ofri1 (AUTHOR), Das, Koyeli2 (AUTHOR), Wiener, Reuven3 (AUTHOR), Lehming, Norbert1 (AUTHOR), Pines, Ophry1,2 (AUTHOR) ophryp@ekmd.huji.ac.il
Publikováno v:
Cells (2073-4409). Dec2022, Vol. 11 Issue 24, p4109. 21p.
Publikováno v:
The Journal of Biological Chemistry
Mitochondrial protein translocation is an intricately regulated process that requires dedicated translocases at the outer and inner membranes. The presequence translocase complex, translocase of the inner membrane 23, facilitates most of the import o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::762162a259c5ff20569998a55943f575
https://doi.org/10.1016/j.jbc.2021.101349
https://doi.org/10.1016/j.jbc.2021.101349
Publikováno v:
The Journal of Biological Chemistry
Mitochondria are essential organelles that carry out a number of pivotal metabolic processes and maintain cellular homeostasis. Mitochondrial dysfunction caused by various stresses is associated with many diseases such as type 2 diabetes, obesity, ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863dbecbc7c5145aaab80029becd9a14
https://doi.org/10.1016/j.jbc.2021.101279
https://doi.org/10.1016/j.jbc.2021.101279
Autor:
Barbora Keresztesová, Jozef Nosek, Katerina Hanakova, Jan Frankovsky, Katarina Prochazkova, Peter Barath, Jana Bellova, Vladimír Pevala, Veronika Lukáčová, Lubomir Tomaska, Eva Kutejová, Jacob A. Bauer, Gabriela Ondrovičová, Nina Kunová, Nikola Čanigová, Zbynek Zdrahal, Barbara Sivakova
Publikováno v:
The Journal of Biological Chemistry
Acylation modifications, such as the succinylation of lysine, are post-translational modifications and a powerful means of regulating protein activity. Some acylations occur nonenzymatically, driven by an increase in the concentration of acyl group d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::760fd1f464b73b43d5049deeac5004db
https://doi.org/10.1016/j.jbc.2021.101155
https://doi.org/10.1016/j.jbc.2021.101155
Autor:
Frans A. Kuypers, Markus Islinger, Suzan Kors, Eric Soupene, Michael Schrader, Tim P. Levine, Joseph L. Costello
Publikováno v:
Biochimica et Biophysica Acta. Molecular Cell Research
Members of the large multigene family of acyl-CoA binding domain containing proteins (ACBDs) share a conserved motif required for binding of Coenzyme A esterified fatty acids of various chain length. These proteins are present in the three kingdoms o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578dcc631d7aeb41407394b7f982fd7b
https://pubmed.ncbi.nlm.nih.gov/32044385
https://pubmed.ncbi.nlm.nih.gov/32044385
Autor:
Natalie M. Niemi, David J. Pagliarini
Publikováno v:
The Journal of Biological Chemistry
More than half a century ago, reversible protein phosphorylation was linked to mitochondrial metabolism through the regulation of pyruvate dehydrogenase. Since this discovery, the number of identified mitochondrial protein phosphorylation sites has i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c68b73f81bd517bffe410584103fb6ce
https://doi.org/10.1016/j.jbc.2021.100880
https://doi.org/10.1016/j.jbc.2021.100880
Publikováno v:
The Journal of Biological Chemistry
The genetics and pathophysiology of Parkinson's disease (PD) strongly implicate mitochondria in disease aetiology. Elegant studies over the last two decades have elucidated complex molecular signaling governing the identification and removal of dysfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396f66095ce3b2ced18f6e06f43bdbd6
https://doi.org/10.1074/jbc.rev120.014294
https://doi.org/10.1074/jbc.rev120.014294
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 42, Iss, Pp 101055-(2020)
Molecular Metabolism, Vol 42, Iss, Pp 101055-(2020)
Objective Cholesterol plays a pivotal role in mitochondrial steroidogenesis, membrane structure, and respiration. Mitochondrial membranes are intrinsically low in cholesterol content and therefore must be replenished with cholesterol from other subce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a07ade6fa0e786d97737a6b6e2a441
https://doi.org/10.1016/j.molmet.2020.101055
https://doi.org/10.1016/j.molmet.2020.101055
Autor:
Amutha Boominathan, Carter J. Hall, Elizabeth Batiuk, Caitlin J. Lewis, Bhavna Dixit, Matthew S. O'Connor
Publikováno v:
Redox Biology
Redox Biology, Vol 30, Iss, Pp-(2020)
Redox Biology, Vol 30, Iss, Pp-(2020)
Mutations in mitochondrial DNA can be inherited or occur de novo leading to several debilitating myopathies with no curative option and few or no effective treatments. Allotopic expression of recoded mitochondrial genes from the nucleus has potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1854fe5b580e451f444bb837e232253d
https://doi.org/10.1016/j.redox.2020.101429
https://doi.org/10.1016/j.redox.2020.101429