Zobrazeno 1 - 10
of 2 088
pro vyhledávání: '"MTHFR (C677T)"'
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Epidemiological studies have reported that polymorphisms of folate-metabolizing genes have a significant impact on male infertility. However, the results of published studies have come to different conclusions. Objective To determ
Externí odkaz:
https://doaj.org/article/1a85d5747efd4a90b0684878cf18e670
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background and aims H-type hypertension is essential hypertension combined with high homocysteine, and both synergistically increase the risk of cardiovascular and cerebrovascular events. The aim of this study was to investigate the risk fac
Externí odkaz:
https://doaj.org/article/42882f9da5da49208c68ad304756e8fe
Publikováno v:
Annals of Human Biology, Vol 51, Iss 1 (2024)
AbstractBackground Chronic hepatitis B virus (HBV) infection is a severe disease affecting the physical and economic well-being of patients. The relationship between polymorphisms in the MTHFR gene and disease progression following HBV infection rema
Externí odkaz:
https://doaj.org/article/14c19d757d2c4362894bde2846f2e7b0
Publikováno v:
Romanian Journal of Neurology, Vol 23, Iss 2, Pp 166-170 (2024)
Background. Recent data suggests that environmental factors may account for up to 40-50% of the variability in the risk of developing autism spectrum disorder (ASD). Aim. The purpose of this study was to examine the correlation between MTHFR polymorp
Externí odkaz:
https://doaj.org/article/0707f47cd5c441f7ab567c91bd1c5a09
Autor:
Fatma Abozeid, Maysaa Zaki, Wafaa Nagah, Amany Ragab, Aya fathy, Dina Elhammady, Hayam Ghazy, Ahmed Yassen, Mohamed Serria, Omar Ammar, Maha Ragab, Manal Nomir
Publikováno v:
Egyptian Liver Journal, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Liver serves as a hub for key metabolic pathways such as folate cycle that provides one-carbon units for a network of metabolic reactions. Methylenetetrahydrofolate reductase (MTHFR) is a rate limiting enzyme in folate metabolism and thus it
Externí odkaz:
https://doaj.org/article/78d1b9f9873f4636bf16992df8cc344a
Publikováno v:
International Journal of General Medicine, Vol Volume 17, Pp 1221-1231 (2024)
Qie Guo,1 Jia-Lin Sun,1 Ran Li,2 Xiao Li1 1Department of Clinical Pharmacy, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, People’s Republic of China; 2Department of Infectious Diseases, The Affiliated Hospital of Qingdao Univers
Externí odkaz:
https://doaj.org/article/787ddfe470e24666833032846bd36389
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Objective To analyse the relationship between the polymorphisms of the H-type hypertensive methylenetetrahydrofolate reductase (MTHFR) C677T gene and neutrophil gelatinase-associated lipocalin (NGAL) in early kidney injury. Method A total of
Externí odkaz:
https://doaj.org/article/736026c76c224a238ea3a9dd6d495d47
Autor:
Jingwei Zhu, Zhe Wang, Xiaotong Sun, Dan Wang, Xinbo Xu, Liping Yang, Jiangdong Du, Zhimei Zhou, Yanhua Qi, Linfeng Ma
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Valproic acid (VPA) has been widely used as an antiepileptic drug for decades. Although VPA is effective and well-tolerated, long-term VPA treatment is usually associated with hepatotoxicity. However, the underlying mechanisms of VPA-caused hepatotox
Externí odkaz:
https://doaj.org/article/19177b3ef1c94cf6915088758ac3da02
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
ObjectiveCerebral small vessel disease (CSVD) is the most common vascular cause of cognitive impairment. This study aimed to explore the association between MTHFR C677T polymorphism and cognitive impairment in CSVD patients.MethodsDemographic, medica
Externí odkaz:
https://doaj.org/article/c4b7584119504112ac131436e951e709
Autor:
Aleksandra Stanojevic, Jelena Spasic, Mladen Marinkovic, Suzana Stojanovic-Rundic, Radmila Jankovic, Ana Djuric, Jerome Zoidakis, Remond J. A. Fijneman, Sergi Castellvi-Bel, Milena Cavic
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Background: Methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms (SNPs) have been suggested as risk, prognostic, and predictive factors for colorectal cancer in various populations, but have not been validated so far. The aim o
Externí odkaz:
https://doaj.org/article/28344242e5054711ab1e8ccbb4f46225