Výsledky vyhledávání - "MTHFR, methylenetetrahydrofolate reductase"

Akademický článek

Clinical, biochemical, radiological, and genetic profile of patients with homocysteine remethylation pathway defect and spastic paraplegia

Autor: Hansashree Padmanabha, Rohan Mahale, Rita Christopher, Gautham Arunachal, Maya Bhat, Mahammad Samim Mondal, Ram Murthy Anjanappa, Ravindranadh Chowdhary Mundlamuri, Ravi Yadav, Seena Vengalil, Pooja Mailankody, Pavagada S Mathuranath, Sadanandavalli R Chandra, Atchayaram Nalini

Publikováno v: Annals of Indian Academy of Neurology, Vol 24, Iss 6, Pp 908-916 (2021)

Objectives: The objective of this study is to describe the clinical, biochemical, radiological, and genetic profile of patients presenting with progressive spastic paraparesis due to homocysteine remethylation pathway defect. Methods: This was a retr

Externí odkaz: https://doaj.org/article/3d27f9d8a8d74fccb2d9f75e0a83f78f

Zobrazit plný text záznamu

Akademický článek

Folates and antifolates in rheumatoid arthritis

Autor: Jansen Gerrit, Weijers Karin, Blits Marjolein, van der Heijden Joost, Gent Yoony, Al Marjon, van der Laken Conny, Molthoff Carla, Verweij Cor, Voskuijl Alexandre, Lems Willem, Scheper Rik, Peters Godefridus, Ratnam Manohar, Aassaraf Yehuda, Dijkmans Ben

Publikováno v: Pteridines, Vol 24, Iss 1, Pp 21-26 (2013)

Almost all current standard treatment of care for patients with chronic inflammatory diseases such as rheumatoid arthritis (RA) includes the folate antagonist methotrexate (MTX). Despite the proven efficacy of MTX in RA treatment, it is anticipated t

Externí odkaz: https://doaj.org/article/e593d5a56a1546ec9a04bf4a34f6331d

Zobrazit plný text záznamu

CLINICAL FEATURES AND AUTONOMIC DISORDERS IN PATIENTS WITHMIGRAINE WITH POLIMORFIZM OF THE METHYLENEHYDROFOLATE REDUCTASE GENE

Autor: Marks Taxirovich Jabbarov, Nurmamat Yusupovich Khudayberganov

109 sick with migraine are clinical neurologically examined, which were divided into 2 groups: the first group sick with migraine with aura (n - 22); the second group - sick with migraine without aura (n - 87). In addition, a PCR (polymerase chain re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab53007cb8b9852a2795382bbe7e610

Zobrazit plný text záznamu

Clinical, Biochemical, Radiological, and Genetic Profile of Patients with Homocysteine Remethylation Pathway Defect and Spastic Paraplegia

Autor: Atchayaram Nalini, Hansashree Padmanabha, Rohan Mahale, Rita Christopher, Gautham Arunachal, Maya Bhat, MahammadSamim Mondal, RamMurthy Anjanappa, RavindranadhChowdhary Mundlamuri, Ravi Yadav, Seena Vengalil, Pooja Mailankody, PavagadaS Mathuranath, SadanandavalliR Chandra

Publikováno v: Annals of Indian Academy of Neurology, Vol 24, Iss 6, Pp 908-916 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92da068d1c615460dbe2b598eec4039f
https://pubmed.ncbi.nlm.nih.gov/35359558

Zobrazit plný text záznamu

Pregnancy outcomes in women with epilepsy and MTHFR mutations supplemented with methylated folate and methylcobalamin (methylated B12)

Autor: Michael J. Doherty, Nicole M. Warner, Emma M. Lascar

Publikováno v: Epilepsy & Behavior Reports, Vol 15, Iss, Pp 100419-(2021)
Epilepsy & Behavior Reports

Highlights • Folate processing gene (MTHFR) defects are common in women with epilepsy (WWE) and mood disorders. • Methylated versions of folate and B12 may bypass problems related to MTHFR gene processing. • Successful pregnancies occurred in W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4c2259594930c97f5f244a72b05e6f
http://www.sciencedirect.com/science/article/pii/S2589986420300678

Zobrazit plný text záznamu

Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice

Autor: Alice P. Sowton, Andrew J. Murray, Simon James Tunster, Erica D. Watson, Ben D. McNally, Nisha Padmanabhan, Julian L. Griffin, Antonio Murgia, Aisha Yusuf

Publikováno v: Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 23, Iss, Pp-(2020)

Nonalcoholic fatty liver disease (NAFLD) is associated with dietary folate deficiency and mutations in genes required for one‑carbon metabolism. However, the mechanism through which this occurs is unclear. To improve our understanding of this link,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5de79e1f7ef67cef5ce425b58d812c6
http://hdl.handle.net/10044/1/82233

Zobrazit plný text záznamu

Gene interactions observed with the HDL-c blood lipid, intakes of protein, sugar and biotin in relation to circulating homocysteine concentrations in a group of black South Africans

Autor: Jacomina P. du Plessis, Lizelle Zandberg, Cornelie Nienaber-Rousseau, Alida Melse-Boonstra

Publikováno v: Molecular Genetics and Metabolism Reports, 22
Molecular Genetics and Metabolism Reports 22 (2020)
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 22, Iss, Pp-(2020)

Background: Elevated homocysteine (Hcy) is associated with several pathologies. Gene–diet interactions related to Hcy might be used to customize dietary advice to reduce disease incidence. To explore this possibility, we investigated interactions b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e094a32b1cc86c261c27a4bc390a2c80
https://doi.org/10.1016/j.ymgmr.2019.100556

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Polymorphisms of glutathione S-transferase and methylenetetrahydrofolate reductase genes in Moldavian patients with ulcerative colitis: Genotype-phenotype correlation

Autor: Elena Tudor, Alexander Varzari, Svetlana Turcan, Igor V. Deyneko

Publikováno v: Meta Gene

Background Glutathione S-transferases (GSTM1, GSTT1, and GSTP1) and methylenetetrahydrofolate reductase (MTHFR) are important enzymes for protection against oxidative stress. In addition, MTHFR has an essential role in DNA synthesis, repair, and meth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b5ed12efca2a43c708ff63391517ce

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání