Zobrazeno 1 - 10
of 7 141
pro vyhledávání: '"MTHFR"'
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Background Epidemiological studies have reported that polymorphisms of folate-metabolizing genes have a significant impact on male infertility. However, the results of published studies have come to different conclusions. Objective To determ
Externí odkaz:
https://doaj.org/article/1a85d5747efd4a90b0684878cf18e670
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-5 (2024)
Abstract Mutation of methylenetetrahydrofolate reductase (MTHFR) C677T leads to the decrease of folate utilization and the impairment of spermatogenesis. This study attempts to investigate the association between MTHFR C677T polymorphisms and nonobst
Externí odkaz:
https://doaj.org/article/162e5639f6fc45ea84c56af2b3ede1f2
Publikováno v:
Dental Journal, Vol 57, Iss 3, Pp 184-188 (2024)
Background: Cleft lip with or without cleft palate (CL/P) is the most common congenital anomaly found in Indonesia. CL/P is caused by hereditary (genetic) and environmental factors. Environmental factors can result in methylation in the promoter of t
Externí odkaz:
https://doaj.org/article/e54fb6c3235e4de4967df205944e5af3
Publikováno v:
Modern Medicine, Vol 31, Iss 3, Pp 227-236 (2024)
Objectives: Objectives: The current study was designed to evaluate the role of MTHFR gene (rs1801133 and rs1801131) polymorphisms and investigate the serum Homocysteine level in Iraqi patients with CKD. Materials and Methods: Blood samples were coll
Externí odkaz:
https://doaj.org/article/de9dd185dc2444f0803fad457643b071
Autor:
Sura F. Alsaffar, Noor Nihad Baqer
Publikováno v:
Iranian Journal of Medical Sciences, Vol 49, Iss 7, Pp 430-440 (2024)
Background: The methylenetetrahydrofolate reductase (MTHFR) gene is an essential gene in the metabolism of folate-homocysteine. Recently, the level of homocysteine was found to be a significant marker in the follow-up of COVID-19 infection. Thus, thi
Externí odkaz:
https://doaj.org/article/f505f74926414197aadd3639f8d3285c
Publikováno v:
BMC Cardiovascular Disorders, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background and aims H-type hypertension is essential hypertension combined with high homocysteine, and both synergistically increase the risk of cardiovascular and cerebrovascular events. The aim of this study was to investigate the risk fac
Externí odkaz:
https://doaj.org/article/42882f9da5da49208c68ad304756e8fe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Analyze the relationship between genetic variations in the MTHFR gene at SNPs (rs1801131 and rs1801133) and the therapy outcomes for Iraqi patients with rheumatoid arthritis (RA). The study was conducted on a cohort of 95 RA Iraqi patients.
Externí odkaz:
https://doaj.org/article/8d17037d576548e5a3e9790c80e43e6d
Publikováno v:
Journal of Men's Health, Vol 20, Iss 6, Pp 51-57 (2024)
The methylenetetrahydrofolate reductase (MTHFR) regulates the metabolism of homocysteine in the human body, and MTHFR C677T polymorphism is correlated with male infertility among Asian populations. The relationship between paternal MTHFR C677T polymo
Externí odkaz:
https://doaj.org/article/a85c7c9fe160455c8e1c09db2f61d879
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 6, Pp 741-745 (2024)
Objective·To study the effects of folic acid and active folate supplementation on red blood cell folate levels in patients with unexplained recurrent pregnancy loss (URPL) and methylenetetrahydrofolate reductase (MTHFR) 677TT genotype.Methods·A tot
Externí odkaz:
https://doaj.org/article/62efbe1065984ac49bd5d155a0267202
Autor:
Fatma Abozeid, Maysaa Zaki, Wafaa Nagah, Amany Ragab, Aya fathy, Dina Elhammady, Hayam Ghazy, Ahmed Yassen, Mohamed Serria, Omar Ammar, Maha Ragab, Manal Nomir
Publikováno v:
Egyptian Liver Journal, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Liver serves as a hub for key metabolic pathways such as folate cycle that provides one-carbon units for a network of metabolic reactions. Methylenetetrahydrofolate reductase (MTHFR) is a rate limiting enzyme in folate metabolism and thus it
Externí odkaz:
https://doaj.org/article/78d1b9f9873f4636bf16992df8cc344a