Zobrazeno 1 - 10
of 89
pro vyhledávání: '"MTBP"'
Autor:
Li Liao, Ling Deng, Yin‐Ling Zhang, Shao‐Ying Yang, Lisa Andriani, Shu‐Yuan Hu, Fang‐Lin Zhang, Zhi‐Min Shao, Da‐Qiang Li
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 11, Pp n/a-n/a (2023)
Abstract Background Triple‐negative breast cancer (TNBC) presents the most challenging subtype of all breast cancers because of its aggressive clinical phenotypes and absence of viable therapy targets. In order to identify effective molecular targe
Externí odkaz:
https://doaj.org/article/bba22e7a57054b5cbc38712a0f7fadb4
Autor:
Paerhati Shayimu, Aikeremu Yusufu, Aizimaiti Rehemutula, Darebai Redati, Rexida Jiapaer, Rousidan Tuerdi
Publikováno v:
Animal Cells and Systems, Vol 25, Iss 3, Pp 152-160 (2021)
Colon cancer is a malignant tumor that seriously affects human health. Recently, studies revealed that the expression of MTBP enhanced the proliferation and metastasis of many types of cancer cells. And the data also showed that MTBP has the potentia
Externí odkaz:
https://doaj.org/article/14fa8d485ebb42959523360e5ed94936
Akademický článek
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Publikováno v:
Open Biology, Vol 11, Iss 10 (2021)
Treslin/Ticrr is required for the initiation of DNA replication and binds to MTBP (Mdm2 Binding Protein). Here, we show that in Xenopus egg extract, MTBP forms an elongated tetramer with Treslin containing two molecules of each protein. Immunodepleti
Externí odkaz:
https://doaj.org/article/7e584a2fa3cf4177b2bad843a1efe827
Autor:
Brian C. Grieb, Christine M. Eischen
Publikováno v:
Biology, Vol 11, Iss 6, p 881 (2022)
The oncogenic transcription factor c-MYC (MYC) is highly conserved across species and is frequently overexpressed or dysregulated in human cancers. MYC regulates a wide range of critical cellular and oncogenic activities including proliferation, meta
Externí odkaz:
https://doaj.org/article/e2616f248e7b485182d5b07a29a15999
Publikováno v:
Biology, Vol 11, Iss 6, p 827 (2022)
The initiation step of replication at replication origins determines when and where in the genome replication machines, replisomes, are generated. Tight control of replication initiation helps facilitate the two main tasks of genome replication, to d
Externí odkaz:
https://doaj.org/article/4fcbec9084d640e9b96cc758e7a6cdb4
Autor:
Akiko Kumagai, William G. Dunphy
Publikováno v:
Cell Reports, Vol 32, Iss 12, Pp 108178- (2020)
Summary: The processes that control where higher eukaryotic cells initiate DNA replication throughout the genome are not understood clearly. In metazoans, the Treslin-MTBP complex mediates critical final steps in formation of the activated replicativ
Externí odkaz:
https://doaj.org/article/b391d66e2be94512b35649cd428e68ce
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Autoinflammatory diseases in dogs are characterized by complex disease processes with varying clinical signs. In Shar-Pei, signs of inflammation including fever and arthritis are known to be related with a breed-specific predispos
Externí odkaz:
https://doaj.org/article/2e9874be4db5469a84ab915d9c29bf88
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
Autor:
Aizimaiti Rehemutula, Aikeremu Yusufu, Darebai Redati, Rousidan Tuerdi, Paerhati Shayimu, Rexida Jiapaer
Publikováno v:
Animal Cells and Systems
article-version (VoR) Version of Record
Animal Cells and Systems, Vol 25, Iss 3, Pp 152-160 (2021)
article-version (VoR) Version of Record
Animal Cells and Systems, Vol 25, Iss 3, Pp 152-160 (2021)
Colon cancer is a malignant tumor that seriously affects human health. Recently, studies revealed that the expression of MTBP enhanced the proliferation and metastasis of many types of cancer cells. And the data also showed that MTBP has the potentia