In Utero and Lactational Exposure to an Environmentally Relevant Mixture of Phthalates Alters Hypothalamic Gene Expression and Sexual Preference in Rats.

Autor: Curi TZ; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), Curitiba, Brazil., Passoni MT; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), Curitiba, Brazil., Tolouei SEL; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), Curitiba, Brazil., de Araújo Ramos AT; Animal Endocrine and Reproductive Physiology Laboratory, Department of Physiology, Federal University of Paraná (UFPR), Curitiba, Brazil., de Almeida SCF; Animal Endocrine and Reproductive Physiology Laboratory, Department of Physiology, Federal University of Paraná (UFPR), Curitiba, Brazil., Romano RM; Reproductive Toxicology Laboratory, Department of Pharmacy, State University of Centro-Oeste, Guarapuava, Brazil., de Oliveira JM; Reproductive Toxicology Laboratory, Department of Pharmacy, State University of Centro-Oeste, Guarapuava, Brazil., Dalsenter PR; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), Curitiba, Brazil., Martino-Andrade AJ; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), Curitiba, Brazil.; Animal Endocrine and Reproductive Physiology Laboratory, Department of Physiology, Federal University of Paraná (UFPR), Curitiba, Brazil.

Publikováno v: Environmental toxicology [Environ Toxicol] 2025 Jan; Vol. 40 (1), pp. 54-65. Date of Electronic Publication: 2024 Sep 09.

The Analgesic Dipyrone Affects Pregnancy Outcomes and Endocrine-Sensitive Endpoints in Female and Male Offspring Rats.

Autor: Passoni MT; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil., Krebs Ribeiro DC; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil., França de Almeida SC; Animal Endocrine and Reproductive Physiology Laboratory, Department of Physiology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil., Furtado da Costa B; Animal Endocrine and Reproductive Physiology Laboratory, Department of Physiology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil., Grechi N; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil., Lima Tolouei SE; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil., Curi TZ; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil., Degraf Cavallin M; Reproductive Toxicology Laboratory, Department of Medicine, State University of Centro-Oeste, 85040-167 Guarapuava, PR, Brazil., Romano RM; Reproductive Toxicology Laboratory, Department of Medicine, State University of Centro-Oeste, 85040-167 Guarapuava, PR, Brazil., Romano MA; Reproductive Toxicology Laboratory, Department of Medicine, State University of Centro-Oeste, 85040-167 Guarapuava, PR, Brazil., Spercoski KM; Department of Biosciences, Federal University of Paraná (UFPR), 85950-000 Palotina, PR, Brazil., Carvalho Dos Santos A; Histopathology Laboratory, Department of Health Sciences, Federal University of Grande Dourados (UFGD), 79804-970 Dourados, MS, Brazil., Carvalho Souza RI; Histopathology Laboratory, Department of Health Sciences, Federal University of Grande Dourados (UFGD), 79804-970 Dourados, MS, Brazil., Dalsenter PR; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil., Martino-Andrade AJ; Reproductive Toxicology Laboratory, Department of Pharmacology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil.; Animal Endocrine and Reproductive Physiology Laboratory, Department of Physiology, Federal University of Paraná (UFPR), 81531-980 Curitiba, PR, Brazil.

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2022 Apr 26; Vol. 187 (1), pp. 80-92.

The endocrine disrupting effects of sodium arsenite in the rat testis is not mediated through macrophage activation.

Autor: de Araújo-Ramos AT; Department of Physiology, Animal Endocrine and Reproductive Physiology Laboratory, Federal University of Paraná (UFPR), Curitiba, PR, Brazil., Basso CG; Department of Physiology, Animal Endocrine and Reproductive Physiology Laboratory, Federal University of Paraná (UFPR), Curitiba, PR, Brazil., Passoni MT; Department of Pharmacology, Reproductive Toxicology Laboratory, Federal University of Paraná (UFPR), Curitiba, PR, Brazil., Ribeiro DCK; Department of Pharmacology, Reproductive Toxicology Laboratory, Federal University of Paraná (UFPR), Curitiba, PR, Brazil., Spercoski KM; Department of Biosciences, Federal University of Paraná (UFPR), Palotina, PR, Brazil., de Oliveira JM; Department of Pharmacy, Laboratory of Reproductive Toxicology, State University of Centro-Oeste (UNICENTRO), Guarapuava, Brazil., Romano RM; Department of Pharmacy, Laboratory of Reproductive Toxicology, State University of Centro-Oeste (UNICENTRO), Guarapuava, Brazil., Merino C; Department of Biological Sciences, Laboratory of Morphology, State University of Paraná (UNESPAR), Paranaguá, PR, Brazil., Sandri JMM; Department of Biological Sciences, Laboratory of Morphology, State University of Paraná (UNESPAR), Paranaguá, PR, Brazil., de Almeida MF; Department of Biological Sciences, Laboratory of Morphology, State University of Paraná (UNESPAR), Paranaguá, PR, Brazil., Predes FS; Department of Biological Sciences, Laboratory of Morphology, State University of Paraná (UNESPAR), Paranaguá, PR, Brazil., Martino-Andrade AJ; Department of Physiology, Animal Endocrine and Reproductive Physiology Laboratory, Federal University of Paraná (UFPR), Curitiba, PR, Brazil; Department of Pharmacology, Reproductive Toxicology Laboratory, Federal University of Paraná (UFPR), Curitiba, PR, Brazil. Electronic address: anderson.andrade@ufpr.br.

Publikováno v: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2021 Jun; Vol. 102, pp. 1-9. Date of Electronic Publication: 2021 Mar 22.

Effects of Talinum paniculatum (Jacq.) Gaertn. leaf extract on general toxicity and pubertal development of rats.

Autor: Tolouei S; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil.; National Center for Natural Products Research, University of Mississippi, Oxford, MS, USA., da Silva GN; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil., Curi TZ; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil., Passoni MT; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil., Ribeiro D; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil., Meldola HG; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil., Grechi N; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil., Hey GS; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil., Souza R; Histology Laboratory, Faculty of Health Sciences, 186079Federal University of Grande Dourados, Dourados, MS, Brazil., Dos Santos AC; Histology Laboratory, Faculty of Health Sciences, 186079Federal University of Grande Dourados, Dourados, MS, Brazil., Beltrame OC; Department of Veterinary Medicine and Erasto Gaertner Hospital-LAC, 28122Federal University of Paraná, Curitiba, PR, Brazil., Dalsenter PR; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil., Martino-Andrade AJ; Laboratory of Reproductive Toxicology, Department of Pharmacology, 186079Federal University of Paraná, Curitiba, PR, Brazil.; Animal Endocrine and Reproductive Physiology Laboratory, 28122Federal University of Paraná, Curitiba, PR, Brazil., Gasparotto Junior A; Laboratory of Electrophysiology and Cardiovascular Pharmacology, Faculty of Health Sciences, 186079Federal University of Grande Dourados, Dourados, MS, Brazil.

Publikováno v: Human & experimental toxicology [Hum Exp Toxicol] 2021 Jan; Vol. 40 (1), pp. 124-135. Date of Electronic Publication: 2020 Aug 07.

From general toxicology to DNA disruption: A safety assessment of Plinia cauliflora (Mart.) Kausel.

Autor: Palozi RAC; Laboratory of Electrophysiology and Cardiovascular Pharmacology - LEFaC, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., Lorençone BR; Laboratory of Electrophysiology and Cardiovascular Pharmacology - LEFaC, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., Guarnier LP; Laboratory of Electrophysiology and Cardiovascular Pharmacology - LEFaC, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., Romão PVM; Laboratory of Electrophysiology and Cardiovascular Pharmacology - LEFaC, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., Marques AAM; Laboratory of Electrophysiology and Cardiovascular Pharmacology - LEFaC, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., Hulsmeyer APCR; Laboratory of Preclinical Research of Natural Products, Paranaense University, Umuarama, PR, Brazil., Lourenço ELB; Laboratory of Preclinical Research of Natural Products, Paranaense University, Umuarama, PR, Brazil., Tolouei SEL; Laboratory of Reproductive Toxicology, Federal University of Paraná, Curitiba, PR, Brazil., da Silva GN; Laboratory of Reproductive Toxicology, Federal University of Paraná, Curitiba, PR, Brazil., Curi TZ; Laboratory of Reproductive Toxicology, Federal University of Paraná, Curitiba, PR, Brazil., Passoni MT; Laboratory of Reproductive Toxicology, Federal University of Paraná, Curitiba, PR, Brazil., Dalsenter PR; Laboratory of Reproductive Toxicology, Federal University of Paraná, Curitiba, PR, Brazil., de Araújo FHS; Laboratory of Toxicological Assays - LETOX, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., Oesterreich SA; Laboratory of Toxicological Assays - LETOX, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., Souza RIC; Laboratory of Electrophysiology and Cardiovascular Pharmacology - LEFaC, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., Dos Santos AC; Laboratory of Electrophysiology and Cardiovascular Pharmacology - LEFaC, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., de Castilho PF; Laboratory of Applied Microbiology, Faculty of Biological and Environmental Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., de Oliveira KMP; Laboratory of Applied Microbiology, Faculty of Biological and Environmental Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil., Nocchi SR; Laboratório de Produtos Naturais e Espectrometria de Massas (LaPNEM), Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brazil., Silva DB; Laboratório de Produtos Naturais e Espectrometria de Massas (LaPNEM), Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal do Mato Grosso do Sul, Campo Grande, MS, Brazil., Gasparotto Junior A; Laboratory of Electrophysiology and Cardiovascular Pharmacology - LEFaC, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, MS, Brazil. Electronic address: arquimedesjunior@ufgd.edu.br.

Publikováno v: Journal of ethnopharmacology [J Ethnopharmacol] 2020 Aug 10; Vol. 258, pp. 112916. Date of Electronic Publication: 2020 Apr 28.