Výsledky vyhledávání - "MT, metallothionein"

Potential molecular mechanisms of zinc- and copper-mediated antiviral activity on COVID-19

Autor: Rajendra Prasad, Isha Rani, Mini Bhatnagar, Parul Goel, Sunita Manhas, Anmol Goyal, Amit Pal

Publikováno v: Nutrition Research (New York, N.y.)

Novel coronavirus disease 2019 (COVID-19) has spread across the globe; and surprisingly, no potentially protective or therapeutic antiviral molecules are available to treat severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. Howev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f43aa8abfb6f77c99dbb29014fa1fa9
http://europepmc.org/articles/PMC8200255

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Redox regulation by reversible protein S-thiolation in Gram-positive bacteria

Autor: Marcel Imber, Agnieszka J. Pietrzyk-Brzezinska, Haike Antelmann

Publikováno v: Redox Biology
Redox Biology, Vol 20, Iss, Pp 130-145 (2019)

Low molecular weight (LMW) thiols play an important role as thiol-cofactors for many enzymes and are crucial to maintain the reduced state of the cytoplasm. Most Gram-negative bacteria utilize glutathione (GSH) as major LMW thiol. However, in Gram-po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f489c6dc700b786fd74ac141fe7a87
http://europepmc.org/articles/PMC6178380

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Resveratrol attenuates testicular apoptosis in type 1 diabetic mice: Role of Akt-mediated Nrf2 activation and p62-dependent Keap1 degradation

Autor: Wenjing Song, Jiancheng Xu, Zongqiang Wang, Jiuwei Cui, Yuguang Zhao, Zhenyu Wang, Xing Jin, Lu Cai, Yuying Li, Ling Bai

Publikováno v: Redox Biology, Vol 14, Iss, Pp 609-617 (2018)
Redox Biology

Infertility is a common complication in diabetic men, mainly due to the loss of germ cells by apoptotic cell death. However, effective and safe approaches to prevent diabetic induction of testicular apoptosis for diabetic patients have not been avail

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ffbe20083322dd2e0e2239cdff1128
https://doi.org/10.1016/j.redox.2017.11.007

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Iron deficiency triggered transcriptome changes in bread wheat

Autor: Jiazhen Gong, Meng Wang, Navreet K. Bhullar

Publikováno v: Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 2709-2722 (2020)
Computational and Structural Biotechnology Journal, 18
Computational and Structural Biotechnology Journal

A series of complex transport, storage and regulation mechanisms control iron metabolism and thereby maintain iron homeostasis in plants. Despite several studies on iron deficiency responses in different plant species, these mechanisms remain unclear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cf17f5137b4cd29708b5b2ec6dbc45

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Transcription factor–driven alternative localization of Cryptococcus neoformans superoxide dismutase

Autor: Sarela García-Santamarina, David R. Loiselle, Dennis J. Thiele, Aaron D. Smith, Martina Ralle, Timothy A.J. Haystead

Publikováno v: The Journal of Biological Chemistry

Cryptococcus neoformans is an opportunistic fungal pathogen whose pathogenic lifestyle is linked to its ability to cope with fluctuating levels of copper (Cu), an essential metal involved in multiple virulence mechanisms, within distinct host niches.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069f940819562d929aab2b57929beaa5
https://doi.org/10.1016/j.jbc.2021.100391

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Heterologous expression of a rice metallothionein isoform (OsMTI-1b) in Saccharomyces cerevisiae enhances cadmium, hydrogen peroxide and ethanol tolerance

Autor: Azar Shahpiri, Zahra Ansarypour

Publikováno v: Brazilian Journal of Microbiology v.48 n.3 2017
Brazilian Journal of Microbiology
Sociedade Brasileira de Microbiologia (SBM)
instacron:SBM
Brazilian Journal of Microbiology, Vol 48, Iss 3, Pp 537-543
Brazilian Journal of Microbiology, Volume: 48, Issue: 3, Pages: 537-543, Published: JUL 2017

Metallothioneins are a superfamily of low-molecular-weight, cysteine (Cys)-rich proteins that are believed to play important roles in protection against metal toxicity and oxidative stress. The main purpose of this study was to investigate the effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb703424164de9342126b609b3c890a

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In vivo Interaction Between Cadmium and Essential Trace Elements Copper and Zinc in Rats

Autor: AYDIN, H. Hakan

Publikováno v: Volume: 31, Issue: 2 127-129
Turkish Journal of Medical Sciences

The complex in vivo interaction between Cd, a toxic metal and essential trace elements, mainly Zn and Cu, has not been elucidated yet. The objective being the elucidation of this interrelationship, Cd was subcutaneously administered as CdCI2 (1 mg/kg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=tubitakulakb::5d91108f838fb6578b4eb8e6156b0631
https://dergipark.org.tr/tr/pub/tbtkmedical/issue/12365/148246

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Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

Autor: Maud E. S. Achard, Sian L. Stafford, Alastair G. McEwan, Ronan Kapetanovic, Nilesh J. Bokil, Matthew J. Sweet, Mark A. Schembri

Publikováno v: Bioscience Reports, Vol 33, Iss 4, p e00049 (2013)
Scopus-Elsevier
Bioscience Reports

The immunomodulatory and antimicrobial properties of zinc and copper have long been appreciated. In addition, these metal ions are also essential for microbial growth and survival. This presents opportunities for the host to either harness their anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867cebb3d5a32f9e9bb61fd2445ba627
http://www.bioscirep.org/bsr/033/e049/bsr033e049.htm

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