Zobrazeno 1 - 7
of 7
pro vyhledávání: '"MSNA, muscle sympathetic nerve activity"'
Autor:
Yrsa Bergmann Sverrisdóttir, George Hadjipavlou, Alexander L. Green, Alexander R. Kent, Sean Martin, David J. Paterson, James J. FitzGerald
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • DRGS at upper lumbar levels significantly reduces sympathetic nerve firing • Reduction in sympathetic activity appears to be independent to pain relief • DRGS significantly reduced BP at 6 months and 2 years
Highlights • DRGS at upper lumbar levels significantly reduces sympathetic nerve firing • Reduction in sympathetic activity appears to be independent to pain relief • DRGS significantly reduced BP at 6 months and 2 years
Autor:
Vera Maria Morsch, Karine Paula Reichert, Milagros Fanny Vera Castro, Naiara Stefanello, Vanessa Valéria Miron, Andréia Machado Cardoso, Maria Rosa Chitolina Schetinger, Charles Elias Assmann, Nathieli B. Bottari
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss, Pp 111273-(2021)
Biomedicine & Pharmacotherapy
Biomedicine & Pharmacotherapy
Graphical abstract
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica
Highlights • The coexistence of diabetes and hypertension represents a major risk factor for the onset of cardiovascular problems. • The purinergic signaling pathway constitutes a ubiquitous system of cell–cell communica
Autor:
Krzysztof, Narkiewicz, Laura E K, Ratcliffe, Emma C, Hart, Linford J B, Briant, Marzena, Chrostowska, Jacek, Wolf, Anna, Szyndler, Dagmara, Hering, Ana P, Abdala, Nathan, Manghat, Amy E, Burchell, Claire, Durant, Melvin D, Lobo, Paul A, Sobotka, Nikunj K, Patel, James C, Leiter, Zoar J, Engelman, Angus K, Nightingale, Julian F R, Paton
Publikováno v:
Jacc. Basic to Translational Science
Summary Animal and human data indicate pathological afferent signaling emanating from the carotid body that drives sympathetically mediated elevations in blood pressure in conditions of hypertension. This first-in-man, proof-of-principle study tested
Akademický článek
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Autor:
Badrov MB; University Health Network and Sinai Health Division of Cardiology, Department of Medicine, University of Toronto and the Toronto General Hospital Research Institute, Toronto, Ontario, Canada., Notarius CF; University Health Network and Sinai Health Division of Cardiology, Department of Medicine, University of Toronto and the Toronto General Hospital Research Institute, Toronto, Ontario, Canada., Keys E; University Health Network and Sinai Health Division of Cardiology, Department of Medicine, University of Toronto and the Toronto General Hospital Research Institute, Toronto, Ontario, Canada., Floras JS; University Health Network and Sinai Health Division of Cardiology, Department of Medicine, University of Toronto and the Toronto General Hospital Research Institute, Toronto, Ontario, Canada.
Publikováno v:
JACC. Case reports [JACC Case Rep] 2022 Nov 16; Vol. 4 (22), pp. 1501-1503. Date of Electronic Publication: 2022 Nov 16 (Print Publication: 2022).
Autor:
Sverrisdottir YB; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom.; College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates., Martin SC; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom., Hadjipavlou G; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom., Kent AR; Neuromodulation Applied Research, Abbott, Sunnyvale, California., Paterson DJ; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom., FitzGerald JJ; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom., Green AL; Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom.
Publikováno v:
JACC. Basic to translational science [JACC Basic Transl Sci] 2020 Sep 16; Vol. 5 (10), pp. 973-985. Date of Electronic Publication: 2020 Sep 16 (Print Publication: 2020).
Autor:
Narkiewicz K; Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland., Ratcliffe LE; CardioNomics Research Group, Clinical Research & Imaging Centre, University of Bristol and University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom., Hart EC; CardioNomics Research Group, Clinical Research & Imaging Centre, University of Bristol and University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom; School of Physiology, Pharmacology & Neuroscience, Biomedical Sciences, University of Bristol, Bristol, United Kingdom., Briant LJ; CardioNomics Research Group, Clinical Research & Imaging Centre, University of Bristol and University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom., Chrostowska M; Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland., Wolf J; Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland., Szyndler A; Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland., Hering D; Department of Hypertension and Diabetology, Medical University of Gdansk, Gdansk, Poland., Abdala AP; School of Physiology, Pharmacology & Neuroscience, Biomedical Sciences, University of Bristol, Bristol, United Kingdom., Manghat N; CardioNomics Research Group, Clinical Research & Imaging Centre, University of Bristol and University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom., Burchell AE; CardioNomics Research Group, Clinical Research & Imaging Centre, University of Bristol and University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom., Durant C; CardioNomics Research Group, Clinical Research & Imaging Centre, University of Bristol and University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom., Lobo MD; NIHR Barts Cardiovascular Biomedical Research Unit, William Harvey Research Institute, QMUL, Charterhouse Square, London, United Kingdom., Sobotka PA; Department of Internal Medicine, Division of Cardiovascular Diseases, The Ohio State University, Columbus, Ohio., Patel NK; Neurosurgery, North Bristol NHS Trust, Southmead Hospital, Bristol, United Kingdom., Leiter JC; Department of Physiology and Neurobiology, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire., Engelman ZJ; Cibiem, Los Altos, California., Nightingale AK; CardioNomics Research Group, Clinical Research & Imaging Centre, University of Bristol and University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom., Paton JF; School of Physiology, Pharmacology & Neuroscience, Biomedical Sciences, University of Bristol, Bristol, United Kingdom.
Publikováno v:
JACC. Basic to translational science [JACC Basic Transl Sci] 2016 Aug 29; Vol. 1 (5), pp. 313-324. Date of Electronic Publication: 2016 Aug 29 (Print Publication: 2016).