Case report: MSI-H, EGFR mutation, and ground-glass nodules as diffuse pulmonary hematogenous metastases

Autor: Liuer He, Lin Li

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

Ground-glass nodules (GGNs) are generally considered an early stage of lung cancer. The imaging characteristics and curative efficacy of multiple GGNs as metastases remain unclear. Microsatellite instability-high (MSI-H) is a biomarker for immunother

Externí odkaz: https://doaj.org/article/e4bf1fd0ea5145ec95a85966e5125024

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Interassay and interobserver comparability study of four programmed death-ligand 1 (PD-L1) immunohistochemistry assays in triple-negative breast cancer

Autor: Alexander Hapfelmeier, Sebastian Foersch, Siranush Karapetyan, Daniel-Christoph Wagner, Katja Steiger, Kristina Schwamborn, Marion Kiechle, Wilko Weichert, Wilfried Roth, Dirk Oettler, Aurelia Noske

Publikováno v: Breast, Vol 60, Iss, Pp 238-244 (2021)
The Breast : Official Journal of the European Society of Mastology

Different immunohistochemical programmed death-ligand 1 (PD-L1) assays and scorings have been reported to yield variable results in triple-negative breast cancer (TNBC). We compared the analytical concordance and reproducibility of four clinically re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a50b5eac3f8c4ff158e8c3f6dfcb0c
http://www.sciencedirect.com/science/article/pii/S0960977621009851

Lactobacillus rhamnosus GG Orchestrates an Antitumor Immune Response

Autor: Rheinallt M. Jones, Bejan Saeedi, Richard U. Eboka, Trevor Darby, Joshua A. Owens, Crystal Naudin, Sarah Hunter-Chang, Maria E. Barbian, Lauren Askew, Brian S. Robinson

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 4, Pp 1311-1327 (2021)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims In colorectal cancer, approximately 95% of patients are refractory to immunotherapy because of low antitumor immune responses. Therefore, there is an exigent need to develop treatments that increase antitumor immune responses and de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a2842f4bdfc40a2fd1a616f50f932c
https://doi.org/10.1016/j.jcmgh.2021.06.001

Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer

Autor: Cheng Liu, Ann-Marie Patch, Lambros T. Koufariotis, Vicki L. J. Whitehall, Jennifer Borowsky, Stephen H. Kazakoff, John V. Pearson, Catherine Bond, Nicola Waddell, Barbara A. Leggett, Diane McKeone, Lochlan Fennell, Alexandra M. Kane

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 2, Pp 120-128 (2020)
Neoplasia (New York, N.Y.)

The serrated neoplasia pathway gives rise to a distinct subgroup of colorectal cancers distinguished by the presence of mutant BRAFV600E and the CpG Island Methylator Phenotype (CIMP). BRAF mutant CRC are commonly associated with microsatellite insta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260bfe1ede9704d895b5f687e5f51c6b
https://doi.org/10.1016/j.neo.2019.12.002