Zobrazeno 1 - 10
of 12 231
pro vyhledávání: '"MSCs"'
Autor:
Yukang Wu, Jianguo Li, Ke Feng, Ailing Tan, Yingying Gao, Wen Chen, Wenwen Jia, Xudong Guo, Jiuhong Kang
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Background The efficiency of mesenchymal stem cells (MSCs) in treating myocardial infarction (MI) remains inconsistent, which limits their therapeutic applications. Therefore, exploring the mechanism for the inconsistent efficacy of MSCs and
Externí odkaz:
https://doaj.org/article/4a70f36ef68d4e36ad55ae573854c4f7
Autor:
Nehal M. Elsherbiny, Mohamed S. Abdel-Maksoud, Kousalya Prabahar, Zuhair M. Mohammedsaleh, Omnia A. M. Badr, Arigue A. Dessouky, Hoda A. Salem, Omnia A. Refadah, Ayman Samir Farid, Ashraf A. Shamaa, Nesrine Ebrahim
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-15 (2024)
Abstract Chemotherapy detrimentally impacts fertility via depletion of follicular reserves in the ovaries leading to ovarian failure (OF) and development of estrogen deficiency-related complications. The currently proposed options to preserve fertili
Externí odkaz:
https://doaj.org/article/e924acb659c84b26925706ad456bb293
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Background Inflammatory bowel disease (IBD) poses a significant and growing global health challenge, affecting both humans and domestic cats. Research on feline IBD has not kept pace with its widespread prevalence in human populations. This
Externí odkaz:
https://doaj.org/article/e7a18f999b1b4ac2bdab9ad9877af00a
Autor:
Jingrou Chen, Shujuan Xie, Dongbo Qiu, Maosheng Xie, Mengye Wu, Xiaoping Li, Xiaoran Zhang, Qili Wu, Yi Xiong, Changyou Wu, Jie Ren, Yanwen Peng
Publikováno v:
Journal of Advanced Research, Vol 65, Iss , Pp 125-136 (2024)
Introduction: Numerous studies demonstrated that NLRP3 has been implicated in the pathogenesis of inflammatory bowel disease (IBD). Mesenchymal stem cells (MSCs) regulated the NLRP3 inflammasome, which has emerged as a novel therapeutic approach for
Externí odkaz:
https://doaj.org/article/86b11c09bd6c47b39b2be98d18c33c61
Autor:
Marwa I. Salman, PhD, Eman G. Khalil, PhD, Aous K. Almzaien, MSc, Ali A. Hadi, PhD, Aysar A. Ahmed, BSc, Hiba K. Shaker, BSc, Ahmed M. Al-Shammari, PhD
Publikováno v:
Journal of Taibah University Medical Sciences, Vol 19, Iss 5, Pp 1011-1023 (2024)
الملخص: أهداف البحث: تعد إصابات واضطرابات العضلات الهيكلية تحديات سريرية عالمية ذات آليات مباشرة وغير مباشرة وتأثيرات متبقية ملحوظة، مث
Externí odkaz:
https://doaj.org/article/8230d68f22f64463b8eb7a6f66efb6f7
Autor:
Yifang Li, Alex Hunter, Miqdad M. Wakeel, Guizhi Sun, Ricky W. K. Lau, Brad R. S. Broughton, Ivan E. Oyarce Pino, Zihao Deng, Tingfang Zhang, Padma Murthi, Mark P. Del Borgo, Robert E. Widdop, Jose M. Polo, Sharon D. Ricardo, Chrishan S. Samuel
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Background Kidney fibrosis is a hallmark of chronic kidney disease (CKD) and compromises the viability of transplanted human bone marrow-derived mesenchymal stromal cells (BM-MSCs). Hence, BM-MSCs were genetically-engineered to express the a
Externí odkaz:
https://doaj.org/article/d6c0ff1090e149c8a2dd546898ac8e05
Autor:
July Constanza Buitrago, Sarah L. Morris, Astrid Backhaus, Gesa Kaltenecker, Jagan Mohan Kaipa, Cyrille Girard, Stefan Schneider, Jens Gruber
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Induced pluripotent stem cell (iPSC)-derived mesenchymal stromal cells (iMSCs) offer a promising alternative to primary mesenchymal stromal cells (MSCs) and their derivatives, particularly extracellular vesicles (EVs), for use in advanced th
Externí odkaz:
https://doaj.org/article/205e2a97979849688a60c665a5ad8867
Autor:
Masatoshi Murayama, Simon K. Chow, Max L. Lee, Bill Young, Yasemin S. Ergul, Issei Shinohara, Yosuke Susuki, Masakazu Toya, Qi Gao, Stuart B. Goodman
Publikováno v:
Bone & Joint Research, Vol 13, Iss 9, Pp 462-473 (2024)
Bone regeneration and repair are crucial to ambulation and quality of life. Factors such as poor general health, serious medical comorbidities, chronic inflammation, and ageing can lead to delayed healing and nonunion of fractures, and persistent bon
Externí odkaz:
https://doaj.org/article/7e07d74a61e74f8081ab24fb0cb29b67
Autor:
Lan Zhao, Beibei Ni, Jinqing Li, Rui Liu, Qi Zhang, Zhuangbin Zheng, Wenjuan Yang, Wei Yu, Lijun Bi
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background The selection of suitable culture medium is critical for achieving good clinical outcomes in cell therapy. To support the commercial application of stem cell therapy, customized culture media not only need to promote stem cell pro
Externí odkaz:
https://doaj.org/article/85aa77ba9c244a769448673b1eb30ce5
Autor:
Jing He, Chunchun Ao, Mao Li, Taoran Deng, Shuo Zheng, Ke Zhang, Chengshu Tu, Yu Ouyang, Ruibo Lang, Yijia Jiang, Yifan Yang, Changyong Li, Dongcheng Wu
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Background Emerging evidence has highlighted the therapeutic potential of human umbilical cord mesenchymal stem cells (UC-MSCs) in chemotherapy-induced premature ovarian failure (POF). This study was designed to investigate the appropriate t
Externí odkaz:
https://doaj.org/article/95d9dd0fb08f4386b9ee509f3a2734fb