Zobrazeno 1 - 10
of 12 285
pro vyhledávání: '"MSCs"'
Autor:
Jingrou Chen, Shujuan Xie, Dongbo Qiu, Maosheng Xie, Mengye Wu, Xiaoping Li, Xiaoran Zhang, Qili Wu, Yi Xiong, Changyou Wu, Jie Ren, Yanwen Peng
Publikováno v:
Journal of Advanced Research, Vol 65, Iss , Pp 125-136 (2024)
Introduction: Numerous studies demonstrated that NLRP3 has been implicated in the pathogenesis of inflammatory bowel disease (IBD). Mesenchymal stem cells (MSCs) regulated the NLRP3 inflammasome, which has emerged as a novel therapeutic approach for
Externí odkaz:
https://doaj.org/article/86b11c09bd6c47b39b2be98d18c33c61
Autor:
Yifang Li, Alex Hunter, Miqdad M. Wakeel, Guizhi Sun, Ricky W. K. Lau, Brad R. S. Broughton, Ivan E. Oyarce Pino, Zihao Deng, Tingfang Zhang, Padma Murthi, Mark P. Del Borgo, Robert E. Widdop, Jose M. Polo, Sharon D. Ricardo, Chrishan S. Samuel
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Background Kidney fibrosis is a hallmark of chronic kidney disease (CKD) and compromises the viability of transplanted human bone marrow-derived mesenchymal stromal cells (BM-MSCs). Hence, BM-MSCs were genetically-engineered to express the a
Externí odkaz:
https://doaj.org/article/d6c0ff1090e149c8a2dd546898ac8e05
Autor:
July Constanza Buitrago, Sarah L. Morris, Astrid Backhaus, Gesa Kaltenecker, Jagan Mohan Kaipa, Cyrille Girard, Stefan Schneider, Jens Gruber
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Induced pluripotent stem cell (iPSC)-derived mesenchymal stromal cells (iMSCs) offer a promising alternative to primary mesenchymal stromal cells (MSCs) and their derivatives, particularly extracellular vesicles (EVs), for use in advanced th
Externí odkaz:
https://doaj.org/article/205e2a97979849688a60c665a5ad8867
Autor:
Masatoshi Murayama, Simon K. Chow, Max L. Lee, Bill Young, Yasemin S. Ergul, Issei Shinohara, Yosuke Susuki, Masakazu Toya, Qi Gao, Stuart B. Goodman
Publikováno v:
Bone & Joint Research, Vol 13, Iss 9, Pp 462-473 (2024)
Bone regeneration and repair are crucial to ambulation and quality of life. Factors such as poor general health, serious medical comorbidities, chronic inflammation, and ageing can lead to delayed healing and nonunion of fractures, and persistent bon
Externí odkaz:
https://doaj.org/article/7e07d74a61e74f8081ab24fb0cb29b67
Autor:
Lan Zhao, Beibei Ni, Jinqing Li, Rui Liu, Qi Zhang, Zhuangbin Zheng, Wenjuan Yang, Wei Yu, Lijun Bi
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Background The selection of suitable culture medium is critical for achieving good clinical outcomes in cell therapy. To support the commercial application of stem cell therapy, customized culture media not only need to promote stem cell pro
Externí odkaz:
https://doaj.org/article/85aa77ba9c244a769448673b1eb30ce5
Autor:
Jing He, Chunchun Ao, Mao Li, Taoran Deng, Shuo Zheng, Ke Zhang, Chengshu Tu, Yu Ouyang, Ruibo Lang, Yijia Jiang, Yifan Yang, Changyong Li, Dongcheng Wu
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Background Emerging evidence has highlighted the therapeutic potential of human umbilical cord mesenchymal stem cells (UC-MSCs) in chemotherapy-induced premature ovarian failure (POF). This study was designed to investigate the appropriate t
Externí odkaz:
https://doaj.org/article/95d9dd0fb08f4386b9ee509f3a2734fb
Autor:
Teeanutree Taephatthanasagon, Steven Dwi Purbantoro, Watchareewan Rodprasert, Koranis Pathanachai, Piyawan Charoenlertkul, Rangsini Mahanonda, Noppadol Sa-Ard-lam, Suryo Kuncorojakti, Adretta Soedarmanto, Nabila Syarifah Jamilah, Thanaphum Osathanon, Chenphop Sawangmake, Sirirat Rattanapuchpong
Publikováno v:
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-15 (2024)
Abstract Background The integration of stem cells, signaling molecules, and biomaterial scaffolds is fundamental for the successful engineering of functional bone tissue. Currently, the development of composite scaffolds has emerged as an attractive
Externí odkaz:
https://doaj.org/article/d144a373dff94fc691b81161d9553b91
Autor:
Amany I. Ahmed, Mohamed F. Dowidar, Asmaa F. Negm, Hussein Abdellatif, Asma Alanazi, Mohammed Alassiri, Walaa Samy, Dina Mohamed Mekawy, Eman M. A. Abdelghany, Nesma I. El-Naseery, Mohamed A. Ibrahem, Emad Ali Albadawi, Wed Salah, Mamdouh Eldesoqui, Emil Tîrziu, Iulia Maria Bucur, Ahmed Hamed Arisha, Tarek Khamis
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-21 (2024)
Abstract Ovarian insufficiency is one of the common reproductive disorders affecting women with limited therapeutic aids. Mesenchymal stem cells have been investigated in such disorders before yet, the exact mechanism of MSCs in ovarian regeneration
Externí odkaz:
https://doaj.org/article/12264e85efd9421e80924edd94522be2
Autor:
Xiangxiong Deng, Su Zhang, Quan Qing, Pengfei Wang, Haiyang Ma, Qinghua Ma, Weixiang Zhao, Hanjing Tang, Min Lu
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101739- (2024)
Mesenchymal stem cells (MSCs) have tremendous potential in cell therapy and regenerative medicine. The placenta-derived MSCs (PMSCs) are becoming favorable sources as they are ethically preferable and rich in MSCs. Although several subgroups of PMSCs
Externí odkaz:
https://doaj.org/article/16df5cd5652b408694d30f1b569f4879
Autor:
Zailing Yang, Chuan Tian, Zhixu He, Xiangqing Zhu, Jie He, Hang Pan, Ye Li, Guangping Ruan, XiJun Wu, Xinghua Pan
Publikováno v:
Regenerative Therapy, Vol 27, Iss , Pp 126-169 (2024)
Background: A decrease in the number and activity of thymic epithelial cells (TECs) is an important factor in thymic degeneration. Mesenchymal stem cells (MSCs) treating thymic ageing is a promising strategy, but the DNA methylation modification mech
Externí odkaz:
https://doaj.org/article/7ee33dd2d9ce4ab89356c16d854c398e