Zobrazeno 1 - 10
of 45
pro vyhledávání: '"MSC‐based therapy"'
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Background Systemic sclerosis (SSc) and sclerodermatous graft-versus-host disease (Scl-GVHD)—characterized by similar developmental fibrosis, vascular abnormalities, and innate and adaptive immune response, resulting in severe skin fibrosi
Externí odkaz:
https://doaj.org/article/100613a97de24fb1a35cf6f85a9b623f
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 11, Pp 5153-5172 (2022)
Over the past two decades, mesenchymal stem cells (MSCs) have shown promising therapeutic effects both in preclinical studies (in animal models of a wide range of diseases) and in clinical trials. However, the efficacy of MSC-based therapy is not alw
Externí odkaz:
https://doaj.org/article/4c262d6d699a47b897870af69e8627f1
Autor:
Chao Gao, Xiaodong Wang, Jian Lu, Zhilin Li, Haowen Jia, Minghao Chen, Yuchen Chang, Yanhong Liu, Peiyuan Li, Baotong Zhang, Xuezhi Du, Feng Qi
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Abstract Background Mesenchymal stem cells (MSCs) have become a promising candidate for cell-based immune therapy for acute rejection (AR) after heart transplantation due to possessing immunomodulatory properties. In this study, we evaluated the effi
Externí odkaz:
https://doaj.org/article/d212b2ed9d09431995f6b4adb8a3432e
Publikováno v:
EBioMedicine, Vol 69, Iss , Pp 103427- (2021)
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease characterized by synovial inflammation and progressive joint destruction and is a primary cause of disability worldwide. Despite the existence of numerous anti-rheumatic drugs, a sign
Externí odkaz:
https://doaj.org/article/004c9a5dd0214232a30b78bcf6219b99
Autor:
Bryan Falcones, Zackarias Söderlund, Arturo Ibáñez-Fonseca, Isaac Almendros, Jordi Otero, Ramon Farré, Sara Rolandsson Enes, Linda Elowsson Rendin, Gunilla Westergren-Thorsson
Publikováno v:
Cells, Vol 11, Iss 12, p 1866 (2022)
Mesenchymal stromal cell (MSC)-based therapies for inflammatory diseases rely mainly on the paracrine ability to modulate the activity of macrophages. Despite recent advances, there is scarce information regarding changes of the secretome content att
Externí odkaz:
https://doaj.org/article/0b3b2ddf9ca04128b2c946385a39c7a8
Current status and potential challenges of mesenchymal stem cell-based therapy for malignant gliomas
Autor:
Qing Zhang, Wei Xiang, Dong-ye Yi, Bing-zhou Xue, Wan-wan Wen, Ahmed Abdelmaksoud, Nan-xiang Xiong, Xiao-bing Jiang, Hong-yang Zhao, Peng Fu
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-9 (2018)
Abstract Glioma, which accounts for more than 30% of primary central nervous system tumours, is characterised by symptoms such as headaches, epilepsy, and blurred vision. Glioblastoma multiforme is the most aggressive, malignant, and lethal brain tum
Externí odkaz:
https://doaj.org/article/b7bba83aa93343708bab3a2026285f28
Autor:
Peiyuan Li, Minghao Chen, Baotong Zhang, Yanhong Liu, Jian Lu, Feng Qi, Chao Gao, Yuchen Chang, Zhilin Li, Xiaodong Wang, Xuezhi Du, Haowen Jia
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-15 (2020)
Stem Cell Research & Therapy
Stem Cell Research & Therapy
Background Mesenchymal stem cells (MSCs) have become a promising candidate for cell-based immune therapy for acute rejection (AR) after heart transplantation due to possessing immunomodulatory properties. In this study, we evaluated the efficacy of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4135b8ae5cbeae2ec83f1c9c21afd55
http://link.springer.com/article/10.1186/s13287-020-01752-1
http://link.springer.com/article/10.1186/s13287-020-01752-1
Akademický článek
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Akademický článek
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Autor:
Hartmut Geiger, Karin Scharffetter-Kochanek, Karmveer Singh, Saira Munir, Linda Krug, Gudrun Strauss, Dongsheng Jiang, Abhijit Basu, Pallab Maity, Meinhard Wlaschek, Philipp Haas
Publikováno v:
EMBO Reports
EMBO Rep. 21:e48777 (2020)
EMBO Rep. 21:e48777 (2020)
We here address the question whether the unique capacity of mesenchymal stem cells to re‐establish tissue homeostasis depends on their potential to sense pathogen‐associated molecular pattern and, in consequence, mount an adaptive response in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1539177e33481a599b0ade884d138b74
https://pubmed.ncbi.nlm.nih.gov/32162777
https://pubmed.ncbi.nlm.nih.gov/32162777