Zobrazeno 1 - 10
of 23
pro vyhledávání: '"MS/MS, tandem MS"'
Publikováno v:
Molecular & Cellular Proteomics : MCP
Recent advances in efficiency and ease of implementation have rekindled interest in ion mobility spectrometry, a technique that separates gas phase ions by their size and shape and that can be hybridized with conventional LC and MS. Here, we review t
Autor:
Brian Stevenson, Michal Bassani-Sternberg, George Coukos, Florian Huber, Chloe Chong, Markus Müller, HuiSong Pak, Justine Michaux
Publikováno v:
Molecular & cellular proteomics, vol. 20, pp. 100080
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Mass spectrometry (MS) is the state-of-the-art methodology for capturing the breadth and depth of the immunopeptidome across human leukocyte antigen (HLA) allotypes and cell types. The majority of studies in the immunopeptidomics field are discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3887a4cb5b29beb1c402fbcb2034206b
https://serval.unil.ch/notice/serval:BIB_DCFCF966CE50
https://serval.unil.ch/notice/serval:BIB_DCFCF966CE50
Autor:
Drew M, Nassal, Nehal J, Patel, Sathya D, Unudurthi, Rebecca, Shaheen, Jane, Yu, Peter J, Mohler, Thomas J, Hund
Publikováno v:
The Journal of Biological Chemistry
Fibrosis is a pronounced feature of heart disease and the result of dysregulated activation of resident cardiac fibroblasts (CFs). Recent work identified stress-induced degradation of the cytoskeletal protein βIV-spectrin as an important step in CF
Autor:
Yue Qi, Mohammad Haghir Ebrahimabadi, Khoa D. Nguyen, Shaojian Gao, Tapan K. Maity, Xu Zhang, Vikram Misra, Udayan Guha, Javed Khan, Constance M. Cultraro, Cenk Sahinalp, David Milewski, Catherine Ade, Ken-ichi Hanada, James Chih-Hsin Yang
Publikováno v:
Molecular & Cellular Proteomics : MCP
Immune checkpoint inhibitors and adoptive lymphocyte transfer–based therapies have shown great therapeutic potential in cancers with high tumor mutational burden (TMB), such as melanoma, but not in cancers with low TMB, such as mutant epidermal gro
Publikováno v:
Molecular & Cellular Proteomics : MCP
High-resolution MS-based proteomics generates large amounts of data, even in the standard LC–tandem MS configuration. Adding an ion mobility dimension vastly increases the acquired data volume, challenging both analytical processing pipelines and e
Autor:
Axel Knebel, Lorna Plater, Christoph H. Emmerich, Sam Strickson, Natalia Shpiro, Philip Cohen, David G. Campbell, Maria Stella Ritorto
Publikováno v:
Biochemical Journal
The compound BAY 11-7082 inhibits IκBα [inhibitor of NF-κB (nuclear factor κB)α] phosphorylation in cells and has been used to implicate the canonical IKKs (IκB kinases) and NF-κB in >350 publications. In the present study we report that BAY 1
Autor:
Yoshio Kodera, Tsuneo Takenaka, Pamela K. Carmines, Yoshikazu Aoki, Masanori Yokoba, Tadakazu Maeda, Naohito Ishii, Masato Katagiri, Masamichi Oh-Ishi, Tsuyoshi Ichikawa, Hiroyuki Imaizumi, Hideki Ikenagasa
Publikováno v:
Clinical Science (London, England : 1979)
Experiments were performed to evaluate the hypothesis that ACE (angiotensin-converting enzyme) inhibition (enalapril) suppresses 3-NT (3-nitrotyrosine) production in the renal cortex during the early stage of Type 1 DM (diabetes mellitus) in the rat.
Publikováno v:
Biochemical Journal
Symplocarpus renifolius and Arum maculatum are known to produce significant heat during the course of their floral development, but they use different regulatory mechanisms, i.e. homoeothermic compared with transient thermogenesis. To further clarify
Autor:
Karthik Viswanathan, Akila Jayaraman, Zachary Shriver, Jing Li, Ram Sasisekharan, Xiaoying Koh, Rahul Raman
Publikováno v:
Biochemical Journal
The glycoprotein HA (haemagglutinin) on the surface of influenza A virus plays a central role in recognition and binding to specific host cell-surface glycan receptors and in fusion of viral membrane to the host nuclear membrane during viral replicat
Autor:
Shuai Jiang, Yalin Yin, Yijie Chen, Yi Liang, Guojun Yu, Yamu Li, Man Wang, Barry Hon Cheung Wong, Yongfu Pan, Hui Sun, Bianli Gu
Publikováno v:
Biochemical Journal
A novel lectin was isolated from the mushroom Agrocybe aegerita (designated AAL-2) by affinity chromatography with GlcNAc (N-acetylglucosamine)-coupled Sepharose 6B after ammonium sulfate precipitation. The AAL-2 coding sequence (1224 bp) was identif