Zobrazeno 1 - 10
of 1 922
pro vyhledávání: '"MRNA Sequencing"'
Autor:
Rixt S. Bruinsma, Marta F. Fiocco, Wendy W. J. de Leng, Lennart A. Kester, Karin P. S. Langenberg, Godelieve A. M. Tytgat, Max M. van Noesel, Marc H. W. A. Wijnen, Alida F. W. van der Steeg, Ronald R. de Krijger
Publikováno v:
Journal of Molecular Pathology, Vol 5, Iss 3, Pp 304-318 (2024)
ALK is related to poor survival in neuroblastoma patients. We investigated the prognostic relevance of ALK mRNA expression and the relationship with ALK immunohistochemical expression, histological subtype and ALK aberrations. Whole transcriptome seq
Externí odkaz:
https://doaj.org/article/7650c5ee68724d7986d26e5dc5cc04ca
Autor:
Mi Zhang, Yuhao Duan, Hui Gan, Ning Jiang, Le Qin, Yujia Luo, Ailiyaer Palahati, Yaying He, Chenyang Li, Xuan Zhai
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The development of intracerebral hemorrhage (ICH) is a dynamic process and intervention during the acute phase of ICH is critical for subsequent recovery. Therefore, it is crucial to screen potential signature genes and therapeutic target ge
Externí odkaz:
https://doaj.org/article/5084c3356b7741e1a00e4807c5764e74
Autor:
Liying Zhu, Bo Wang, Jin Gu, Jiayu Zhou, Yuan Wu, Wei Xu, Min Yang, Xia Cai, Hongbo Shen, Lu Lu, Feifei Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cytokine of interferon-gamma (IFNγ) plays a vital role in the immune response against Mycobacteria tuberculosis (Mtb) infection, yet the specific function of T cells producing IFNγ in this process remains unclear. In this study, we first isolated I
Externí odkaz:
https://doaj.org/article/7bc444e0423a440591229f8cf3419336
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Wolbachia is an obligate endosymbiont that is maternally inherited and widely distributed in arthropods and nematodes. It remains in the mature eggs of female hosts over generations through multiple strategies and manipulates the reproductio
Externí odkaz:
https://doaj.org/article/70bdff749c454042a47f2774dba1eb4c
Autor:
Anetta Kuczyńska, Martyna Michałek, Piotr Ogrodowicz, Michał Kempa, Natalia Witaszak, Michał Dziurka, Damian Gruszka, Agata Daszkowska-Golec, Iwona Szarejko, Paweł Krajewski, Krzysztof Mikołajczak
Publikováno v:
Plant Signaling & Behavior, Vol 19, Iss 1 (2024)
One of the main signal transduction pathways that modulate plant growth and stress responses, including drought, is the action of phytohormones. Recent advances in omics approaches have facilitated the exploration of plant genomes. However, the molec
Externí odkaz:
https://doaj.org/article/d571704924f7476c969d49cdb7e70bb3
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
ObjectiveThis study aims to investigate the pathogenesis of hyperglycemia and its associated vasculopathy using multiomics analyses in diabetes and impaired glucose tolerance, and validate the mechanism using the cell experiments.MethodsIn this study
Externí odkaz:
https://doaj.org/article/0a19308f360e4bf5bed083fb3c7c6fff
Autor:
Yaping Yu, Yonghao Fan, Wenli Mei, Xiaoqing Xu, Yan Chen, Yangyang Zhao, Banzhan Ruan, Zhihua Shen, Yanda Lu, Shaojiang Zheng, Wei Jie
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 177, Iss , Pp 117013- (2024)
Objective: Dendrobin A, a typical active ingredient of the traditional Chinese medicine Dendrobium nobile, has potential clinical application in cancer treatment; however, its effect and mechanism in anti-hepatocellular carcinoma (HCC) remain unsolve
Externí odkaz:
https://doaj.org/article/d0bf0c3580854e24ba32e3ab54d68767
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
BackgroundTuberculosis is a worldwide epidemic disease, posing a serious threat to human health. To find effective drug action targets for Mycobacterium tuberculosis, differentially expressed genes in tuberculosis patients and healthy people were scr
Externí odkaz:
https://doaj.org/article/bc3c9bb812cb498ca96ecfbbf78182dd
Autor:
Kevin C. Bermea, Carolina Duque, Charles D. Cohen, Aashik Bhalodia, Sylvie Rousseau, Jana Lovell, Marcelle Dina Zita, Monica R. Mugnier, Luigi Adamo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionGrowing evidence from animal models indicates that the myocardium hosts a population of B cells that play a role in the development of cardiomyopathy. However, there is minimal data on human myocardial B cells in the context of cardiomyop
Externí odkaz:
https://doaj.org/article/4968b5d4316d44de80d4aa0da3f4b62a
Autor:
Michael Svensson, Alen Lovric, Torbjörn Åkerfeldt, David Hellsten, Tara Haas, Thomas Gustafsson, Eric Rullman
Publikováno v:
Physiological Reports, Vol 12, Iss 7, Pp n/a-n/a (2024)
Abstract Exercise has different effects on different tissues in the body, the sum of which may determine the response to exercise and the health benefits. In the present study, we aimed to investigate whether physical training regulates transcription
Externí odkaz:
https://doaj.org/article/64f0ff24627c4717a95d96aba1d65b3b