Zobrazeno 1 - 10
of 702
pro vyhledávání: '"MRGPRX2"'
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 7099-7110 (2024)
Chenrui Zhao,1,2,* Yuanyuan Ding,2,* Yihan Huang,2 Chao Wang,2 Bin Guo,1 Tao Zhang2 1Department of Anesthesiology, Xi’an Honghui Hospital, Xi’an Jiaotong University, Xi’an, 710054, People’s Republic of China; 2College of Pharmacy, Xi
Externí odkaz:
https://doaj.org/article/229a17bf4b9341d8a2c29de65fd69363
Autor:
Colin H. Macphee, Xinzhong Dong, Qi Peng, Daniel V. Paone, Per Stahl Skov, Katrine Baumann, Theresa Roethke, Deborah A. Goldspink, Samuel K. Pearson, Zining Wu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionBecause MRGPRX2 is now recognized as the mast cell receptor for basic secretagogues, there is currently a tremendous interest in whether MRGRPX2 could play an important role in various pruritic dermatoses such as chronic spontaneous urtic
Externí odkaz:
https://doaj.org/article/7ca26fa053aa43d89ee499f20b3dde40
Publikováno v:
Journal of Xenobiotics, Vol 14, Iss 1, Pp 380-403 (2024)
Mast cells (MCs) are immune cells that reside in tissues; particularly in the skin, and in the gastrointestinal and respiratory tracts. In recent years, there has been considerable interest in the Mas-Related G Protein-Coupled Receptor X2 (MRGPRX2),
Externí odkaz:
https://doaj.org/article/e4244d64356f4358ab80369d29c12d92
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Sinomenine hydrochloride (SH) is commonly used in the treatment of rheumatoid arthritis. It activates mast cells and induces anaphylaxis in the clinical setting. Adverse drug reactions can be caused by activation of MAS-associated G protein-coupled r
Externí odkaz:
https://doaj.org/article/643edd3e18774cd6844052e91bd5d2be
Autor:
Zhuoran Li, Jean Schneikert, Shiva Raj Tripathi, Manqiu Jin, Gürkan Bal, Torsten Zuberbier, Magda Babina
Publikováno v:
Cells, Vol 13, Iss 20, p 1681 (2024)
Skin mast cells (MCs) mediate acute allergic reactions in the cutaneous environment and contribute to chronic dermatoses, including urticaria, and atopic or contact dermatitis. The cAMP response element binding protein (CREB), an evolutionarily well
Externí odkaz:
https://doaj.org/article/c3e787b5da6d4454992719812e83af44
Autor:
Yitao Gong, Anna-Karin Johnsson, Jesper Säfholm, Mamdoh Al-Ameri, Erik Sachs, Kasra Vali, Gunnar Nilsson, Elin Rönnberg
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundMast cells are critically involved in IgE-mediated diseases, e.g., allergies and asthma. Human mast cells are heterogeneous, and mast cells from different anatomical sites have been shown to respond differently to certain stimuli and drugs.
Externí odkaz:
https://doaj.org/article/61dd0c7e65ac475988e6a5ad6d7f8986
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionAtopic dermatitis (AD) is a chronic inflammatory skin disorder characterised by itching, erythema, and epidermal barrier dysfunction. The pathogenesis of AD is complex and multifactorial; however,mast cell (MC) activation has been reporte
Externí odkaz:
https://doaj.org/article/2e77c22d6b5f4a17a979f18c7cfb95d3
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Initiation of the bradykinin generation cascade is responsible for the occurrence of attacks in some types of angioedema without wheals. Hereditary angioedema due to C1 inhibitor deficiency (HAE-C1-INH) is one such clinical entity. In this paper, we
Externí odkaz:
https://doaj.org/article/fa2e6dc15b544ec68200b87b566e0cfd